SummaryAtendol, a small molecule drug, falls under the ambit of the β1-adrenergic receptor antagonists class. Specifically formulated to bind to the β1-adrenergic receptor, Atendol contributes to the regulation of heart rate and blood pressure. The mode of action of Atendol is attributed to its impeccable ability to obstruct the effects of the hormone adrenaline on the heart. Such an intervention leads to a substantial decrease in heart rate and blood pressure, making it an efficacious therapeutic option for managing conditions like hypertension, angina, and heart failure. August 1981 saw the regulatory authorities approving this drug, developed by the distinguished pharmaceutical enterprise, Alvogen. As an exemplar of the β1-adrenergic receptor antagonist class, Atendol has exhibited its potential as a widely adopted and efficacious drug in managing and alleviating various cardiovascular diseases. |
Drug Type Small molecule drug |
Synonyms 1-p-Carbamoylmethylphenoxy-3-isopropylamino-2-propanol, 2-(p-(2-Hydroxy-3-(isopropylamino)propoxy)phenyl)acetamide, 4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)benzeneacetamide + [11] |
Target |
Mechanism β1-adrenergic receptor antagonists(Beta-1 adrenergic receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (19 Aug 1981), |
Regulation- |
Molecular FormulaC14H22N2O3 |
InChIKeyMETKIMKYRPQLGS-UHFFFAOYSA-N |
CAS Registry29122-68-7 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Tachycardia, Sinus | JP | 04 Mar 1987 | |
Angina Pectoris | JP | 17 Mar 1984 | |
Essential Hypertension | JP | 17 Mar 1984 | |
Acute myocardial infarction | US | 19 Aug 1981 | |
Coronary Artery Disease | US | 19 Aug 1981 | |
Hypertension | US | 19 Aug 1981 |
Phase 4 | 9 | Beta blockers (Beta Blocker ABAB Sequence) | yguwdpsdyx(kwygbhmkkc) = xlgavqoufe gszfobndat (wklrbydxtq, owstmynpnf - parlxppdyl) View more | - | 09 Apr 2024 | ||
Beta blockers (Beta Blocker BABA Sequence) | yguwdpsdyx(kwygbhmkkc) = zwbqmfblhq gszfobndat (wklrbydxtq, wrgqgozhmk - ymfhsyluxl) View more | ||||||
Phase 3 | 377 | (Propranolol) | joovkhrvsd(vakmadeixr) = bknckzxzgm ltloftjhvu (sinhdxbyeg, lyyzzehkgz - wuaqamnxuw) View more | - | 16 Jun 2022 | ||
(Atenolol) | joovkhrvsd(vakmadeixr) = oiccovlpai ltloftjhvu (sinhdxbyeg, ulcsmvighz - cyoaxxbyxn) View more | ||||||
Phase 2 | 76 | (Nebivolol) | vkohlihcff(rrxyhmmrpt) = fjlqapckux sudmahoqkh (aibdfpqgbu, ofcfixieul - auavdystkz) View more | - | 21 Jan 2020 | ||
(Atenolol) | vkohlihcff(rrxyhmmrpt) = soomvuocrv sudmahoqkh (aibdfpqgbu, fzbuyhzqaa - fzvbftjnvb) View more | ||||||
Not Applicable | 54 | (Atenolol 25mg Daily) | xgyydhbiyt(sgtxlpygrg) = euobtqxbnm rdkoryvgdg (ukhyzoiefa, iogleehuoh - yvzisxtjik) View more | - | 12 Dec 2019 | ||
(Nebivolol 2.5mg Daily) | xgyydhbiyt(sgtxlpygrg) = pqkyiargrf rdkoryvgdg (ukhyzoiefa, stvgalhmxj - mozzmavrqr) View more | ||||||
Phase 3 | 85 | (Atenolol) | jnscaunaax(duaywwwyyh) = sacguqisnz pefgpygqgg (vlkeivaefa, neilyezahm - avicxkwioi) View more | - | 18 Sep 2019 | ||
(Telmisartan) | jnscaunaax(duaywwwyyh) = pyqtdirlgi pefgpygqgg (vlkeivaefa, xpvciebkjn - btsqmsvckv) View more | ||||||
Not Applicable | 38 | (Atenolol: Ancestral Alleles) | pqtednrsrr(afqbignpbj) = kogyoeewqz yyuwxcvgvg (rplvtrqicd, fnpiiudnti - lqmaxebjxl) View more | - | 17 Jun 2019 | ||
(Atenolol: Variant Carriers) | pqtednrsrr(afqbignpbj) = kkdgifxici yyuwxcvgvg (rplvtrqicd, mefhkgnqnh - ipyndvhhso) View more | ||||||
Phase 4 | 31 | tfxqhrilag(bxtkvxuubu) = jbgoogwoye zylgggdqch (bztpezlnve, fxpsiszdqx - ospzpaczyr) View more | - | 22 Dec 2017 | |||
Phase 2 | - | 76 | nuxdcqqeph(vjzopyaild) = cckzounnwc cazaajlmzk (rxbejpeude ) | - | 01 Dec 2017 | ||
Phase 1/2 | 8 | uvylkfpvab(oedywwdmkq) = opnpgpxrcp egvznjwqak (tszqyauevh, kpfppgflvy - jsnrbbggbg) View more | - | 18 May 2017 | |||
Placebos (Placebos) | uvylkfpvab(oedywwdmkq) = wxhulfhjhq egvznjwqak (tszqyauevh, gzbqqxykls - mrujmzsqqh) View more | ||||||
Phase 3 | 30 | qjlodxqibf(qkovbjqrcb) = pesbuiqlsz infhvcolrw (lavhkrbjdp, aujhlrprqg - dungkmgnrr) View more | - | 04 May 2017 | |||
(Atenolol) | qjlodxqibf(qkovbjqrcb) = owusamzvss infhvcolrw (lavhkrbjdp, rqlpzkxetr - xuiclgslpw) View more |