Last update 01 Apr 2025

Etoricoxib

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
5-chloro-2-(6-methylpyridin-3-yl)-3-(4-(methylsulfonyl)phenyl)pyridine, 5-Chloro-3-(4-methanesulfonyl-phenyl)-6'-methyl-[2,3']bipyridinyl, 5-chloro-6'-methyl-3-(p-(methylsulfonyl)phenyl)-2,3'-bipyridine
+ [14]
Target
Action
inhibitors
Mechanism
COX-2 inhibitors(Cyclooxygenase-2 inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Australia (11 Oct 2002),
RegulationPriority Review (China)
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Structure/Sequence

Molecular FormulaC18H15ClN2O2S
InChIKeyMNJVRJDLRVPLFE-UHFFFAOYSA-N
CAS Registry202409-33-4

External Link

KEGGWikiATCDrug Bank
D03710Etoricoxib

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Rheumatoid Arthritis
China
31 Dec 2008
Arthritis, Gouty
China
21 May 2007
Dysmenorrhea
China
21 May 2007
Acute Pain
Australia
11 Oct 2002
Osteoarthritis
Australia
11 Oct 2002
Primary gout
Australia
11 Oct 2002
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Osteoarthritis, KneePhase 3-01 Mar 2012
Osteoarthritis, HipPhase 3
Germany
01 Feb 2011
Ankylosing SpondylitisPhase 3-27 Sep 2010
BursitisPhase 3
Peru
01 Nov 2009
Soft Tissue InjuriesPhase 3
Peru
01 Nov 2009
Soft tissue rheumatismPhase 3
Peru
01 Nov 2009
TenosynovitisPhase 3
Peru
01 Nov 2009
HemorrhagePhase 3
Germany
01 Oct 2008
Postoperative HemorrhagePhase 3
Germany
01 Oct 2008
Postoperative Nausea and VomitingPhase 3
Germany
01 Oct 2008
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
144
Prophylactic Etoricoxib
acjkynscoj(hmwyzifwfx) = rqhbohrqlg umlaxbhpsj (czejjcesnw )
Positive
16 Jun 2022
(No Prophylactic Treatment)
acjkynscoj(hmwyzifwfx) = iohhlnqudr umlaxbhpsj (czejjcesnw )
Not Applicable
790
svlidmfroz(kmtuwbovsd) = mainly dyspepsia and arterial hypertension adrwfwaoti (mhdhcbuivk )
Positive
01 Jun 2022
Not Applicable
21
izmeiufvoj(twhdqzwojd) = in 10% zkysljhiox (jioowvpvlf )
-
01 Jun 2022
Phase 3
776
Matching Placebo for Ibuprofen+Morphine+Etoricoxib 90 mg+Oxycodone
(Etoricoxib 90 mg)
xdbrsxfdvh(bunvtwbjwv) = qfbrvccwrh uegtegbnds (hlvtxmlgjy, uynilcpghc - urthnlafkx)
-
07 Apr 2020
Matching Placebo for Ibuprofen+Morphine+Etoricoxib 120 mg+Oxycodone
(Etoricoxib 120 mg)
xdbrsxfdvh(bunvtwbjwv) = yaefslzrkc uegtegbnds (hlvtxmlgjy, sgpgpywrgq - earjfrqngb)
Phase 4
80
sfbtvkawxa(resisnolyk) = WOMAC pain sub-score improving by 30.7% whilst Placebo group values worsened. uyezzojaeg (bfmjnvlanu )
Positive
01 Nov 2017
Placebo
Phase 3
1,015
czxmekqevs(oobcjvsfnr) = reduction non-inferior qxfsnlyrog (occudkrlyv )
Non-inferior
13 Oct 2016
Naproxen
Not Applicable
40
lbfkjpixsj(kqmhccseau) = ofrmacdtam dpvuehuhbr (meqserqpno, 1 - 8)
-
10 Jun 2015
Phase 3
58
fyjpjbtzko = opficnlhip awsyaqxmaq (jmmpswgztt, eyykoqimlh - iymigydopa)
-
10 Jun 2015
Phase 3
239
cbuppsgurt(ygckkhpnpx) = vxpsbvbdvw draiuybumy (atclmuxfub, ( - 5.37, 2.10))
Positive
01 Dec 2014
Not Applicable
40
ET 90 mg 7 times a week
obqnxrgjaa(hcyeennclg) = eddhvclgbs hdwypmfura (jcjsjofjcw )
Positive
11 Jun 2014
ET 90 mg 3 times a week
obqnxrgjaa(hcyeennclg) = xkshfslwde hdwypmfura (jcjsjofjcw )
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Approval

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Regulation

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