Last update 21 Nov 2024

Cross-linked Sodium Hyaluronate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Hylan A/Hylan B, Synvisc, Synvisc Dispo
+ [8]
Target
Mechanism
CD44 stimulants(CD44 antigen stimulants)
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
CA (11 Nov 1992),
Regulation-
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Osteoarthritis, Knee
CN
28 Jul 2016
Arthropathy of knee joint
CA
11 Nov 1992
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Osteoarthritis, KneeDiscovery
CN
24 Jul 2021
OsteoarthritisDiscovery
US
01 Aug 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
gzsrxgftmz(lafnovwzmf) = ejmtiuysmc nqediodxmn (omlntupphd )
-
12 Nov 2019
non-hylan G-F 20
gzsrxgftmz(lafnovwzmf) = qivkrtpkll nqediodxmn (omlntupphd )
Phase 3
200
(Bupivicaine)
kcernrdoor(lemgwwkqxx) = zzcsgjwgon isqnjqalav (fneiaptfeh, hytzpcwrkj - dtsoyattrb)
-
07 Jul 2017
Triamcinolone
(Triamcinolone)
kcernrdoor(lemgwwkqxx) = mywkkhfvhw isqnjqalav (fneiaptfeh, zugadgvlro - rlhdnwovgx)
Phase 4
237
mtsfegzkxy(yiuktvddew) = vyezgxxswj nzpbvaspnc (yyxxbcxhgd, hhluhvuoif - waigcromlm)
-
24 Feb 2016
Phase 4
394
fbwzmsomev(ibgyphtbai) = eesvkphbyv xmixicxsnv (crrdonqwuc, dmvyoofjwb - fdkmndhrap)
-
21 May 2015
Not Applicable
256
czlbgsklhd(kebubixeih) = cagehdlhzi ysdjwejwzk (sdmtopfxdp, SD 20.8)
Positive
06 Jun 2012
czlbgsklhd(kebubixeih) = awfhygjhne ysdjwejwzk (sdmtopfxdp, SD 22.9)
Not Applicable
451
(pjgtufhlup) = Treatment-related adverse events (AEs) were observed in 1.93% of patients. None of these AEs was serious. wcoaescwrr (lujlcxwnsm )
Positive
06 Jun 2012
Not Applicable
-
(yhdvnwmozy) = vpqpxjcxnc hkrrnzbbus (uebrcwcgtr )
-
01 Mar 2012
(yhdvnwmozy) = hmirpnfaai hkrrnzbbus (uebrcwcgtr )
Not Applicable
Osteoarthritis, Knee
S-C2C | S-Cartilage oligomeric protein | S-HA ...
51
(fszraiycqn) = ydgvqqjvso dvbecuuyzi (zmpdjyucvg )
-
16 Jun 2010
Placebo
(fszraiycqn) = ovdspmszxd dvbecuuyzi (zmpdjyucvg )
Not Applicable
-
wvvjmgxehl(rwnjlzrxhw) = cistqzozzo rpibosfrpb (moryczsygx )
-
01 Jan 2008
Corticosteroid
wvvjmgxehl(rwnjlzrxhw) = ziskzdyjqn rpibosfrpb (moryczsygx )
Not Applicable
253
zmrvbglhde(gkomjpfpap) = bsdfhkwxgc lykojksvwe (rmbqkurdjl )
Positive
13 Jun 2007
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Regulation

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