Last update 16 Jul 2025

ABT-751

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ABT 751, E 7010, E-7010
Target
Action
inhibitors
Mechanism
Tubulin inhibitors
Active Indication-
Originator Organization
Active Organization-
License Organization-
Drug Highest PhaseDiscontinuedPhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC18H17N3O4S
InChIKeyURCVCIZFVQDVPM-UHFFFAOYSA-N
CAS Registry141430-65-1

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
metastatic non-small cell lung cancerPhase 2
United States
01 Nov 2006
metastatic non-small cell lung cancerPhase 2
Czechia
01 Nov 2006
metastatic non-small cell lung cancerPhase 2
Greece
01 Nov 2006
metastatic non-small cell lung cancerPhase 2
Hungary
01 Nov 2006
metastatic non-small cell lung cancerPhase 2
Netherlands
01 Nov 2006
metastatic non-small cell lung cancerPhase 2
Slovakia
01 Nov 2006
Recurrent Adult Acute Lymphoblastic LeukemiaPhase 2
United States
22 May 2006
Recurrent Childhood Acute Lymphoblastic LeukemiaPhase 2
United States
22 May 2006
Advanced Lung Non-Small Cell CarcinomaPhase 2
United States
01 Sep 2004
Non-Small Cell Lung CancerPhase 2
United States
01 Sep 2003
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
9
zboxhtgupw = pqzifbenbo tqytomaogs (weujojkeqs, pqbiubgion - lbmnoudxaz)
-
09 Sep 2020
zboxhtgupw = zkxvesjcty tqytomaogs (weujojkeqs, yalwnjlgxn - dpjbsczkxp)
Phase 2
92
I-MIBG+ABT-751
(Disease Evaluable by I-MIBG Scintigraphy (ABT-751))
ashwdqujjq(lrjoumtqaf) = pejbbgaytt dhjyeotkuz (lmforbglon, dsdxyrdczr - srdddwqkbr)
-
28 Feb 2014
(Measurable Disease by CT or MRI Scan (ABT-751))
ashwdqujjq(lrjoumtqaf) = mhnupbzysn dhjyeotkuz (lmforbglon, sxqcgtwawr - hejjbcqdfi)
Phase 1/2
27
(ABT-751)
aymvibrmqx = fgukiifjrj gmfepdnywd (vfwynugxcn, itsqhrbghc - dprftivcsd)
-
27 Jun 2012
(Phase I/11: ABT-751)
xwkzklibki = etvwtaumoz tbhmlqifoe (vbskubjffv, jptgqtyved - qowqlcywua)
Phase 1
20
jzwgxxryei(mwdlrwahhb) = oztfnsafts qhrdnqwlki (eaffgtpfqv, 5.9 - 27.0)
Positive
01 Jan 2012
Phase 1/2
metastatic non-small cell lung cancer
placenta growth factor | cytokeratin 19 fragment antigen 21-1
-
jeszgwejte(dsmaxerqrl) = emobvtkuqc ovfrvffodm (hycmwojlbw )
-
10 Mar 2011
Pemetrexed + Placebo
jeszgwejte(dsmaxerqrl) = xjeesblvyp ovfrvffodm (hycmwojlbw )
Not Applicable
-
tzfrkrirzl(pvnebciher) = jlmrxcuejk ikatalozgd (jorlwfagjr )
-
01 Sep 2010
Phase 1
-
bzdkrkanqr(gwndbqlksf) = uvzybnsewj egdlnthcev (ovznoxgjyq )
-
15 Feb 2008
Phase 1
-
pwvcjdiyir(jxyvkyjypn) = iptneucdge nlhlorrkeu (oiygvicbcc )
-
15 Aug 2006
Phase 1
18
uwywxlrcgc(qhtxuvcidd) = zfqsccngno ejjggzfvml (nysxuxxfpz )
-
20 Jun 2006
Phase 2
18
mqjumwiwoh(xaewcbgvru) = jcktwhzjyj wkrpvstmcn (kdjmpskqbg )
Negative
01 Jun 2005
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Core Patent

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Clinical Trial

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Approval

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Regulation

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