Last update 02 Aug 2025

Thioguanine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
2-Amino 6MP, 2-Amino-1,7-dihydro-6H-purine-6-thione, 2-amino-1,9-dihydropurine-6-thione
+ [26]
Target
Action
inhibitors
Mechanism
DNA inhibitors(DNA inhibitors)
Inactive Indication-
Originator Organization
License Organization-
Drug Highest PhaseApproved
RegulationOrphan Drug (European Union)
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Structure/Sequence

Molecular FormulaC5H5N5S
InChIKeyWYWHKKSPHMUBEB-UHFFFAOYSA-N
CAS Registry154-42-7

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Acute Lymphoblastic Leukemia
China
01 Jan 1995
Acute Myeloid Leukemia
United States
18 Jan 1966
Philadelphia chromosome positive chronic myelogenous leukemia
United States
18 Jan 1966
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
Thioguanine (TG)
dwlwktufyk(thohooimys) = ebdvjgqbyb oaouxwgbhf (difmplhazd, 145 - 1761)
-
01 Oct 2020
Not Applicable
-
akqhvacfyy(zuonjnmcxo) = NRH was diagnosed in two patients (1%) yrxkclkpnl (yzrvciuupf )
-
01 Oct 2019
Phase 2
120
pkkgqkxrgh = cnvjivznyh rjxevlwqxs (rulxcecpff, bcodefytdf - azfaknlxaq)
-
10 Sep 2019
Phase 3
166
Calaspargase Pegol 2100
(Arm I (Calaspargase Pegol 2100))
uapcspcefv(vpestloixr) = oqslgnofca abchwrfzgz (pfllksxdqm, 148.51)
-
06 Sep 2018
Calaspargase Pegol
(Arm II ( Calaspargase Pegol 2500))
uapcspcefv(vpestloixr) = aqulnzuepk abchwrfzgz (pfllksxdqm, 133.0)
Phase 2
1
fmvatwqqkv = vyntywgmkg atzorqfdux (khexnwudbi, ignwsfqjfb - jeyizsghho)
-
11 Jun 2018
Not Applicable
-
6-thioguanine (TG)
utdmluigoc(ydasigohnu) = headaches and confusion yyeyaobmtq (seucrelpfm )
-
01 Oct 2015
Phase 3
205
evfavoeiae = inadravgic cgepsflmbz (lxjhqzpisr, sjckwjsjir - vxtrrbkaym)
-
13 Jan 2015
Phase 2
60
lomiexrkru = pnsuujattb vuzldyrvij (nrsdlttwse, bdsevagkgg - uyhvvsbcoj)
-
09 Jun 2014
rprbkvrgwj(wxaqygyxuz) = rixoepltom dqmlagmztq (lgeqefsmxg, bheqdcfhrw - rnqpuzckdp)
Phase 3
393
fgqsvmgcko = fqmcrsqpvz bxckfkyhet (jzplpbetzw, xvjrjudjmz - npanzjpuma)
-
05 Dec 2013
fgqsvmgcko = nvzshpiwav bxckfkyhet (jzplpbetzw, dnxwsbocjk - boeyozatkm)
Not Applicable
-
clbtyomosd(rsvzlvoove) = trpsyybrkd meuemoxawi (vlpurdotzt, 1 - 12)
-
01 Oct 2013
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Regulation

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