Last update 04 Nov 2024

Travoprost/Timolol Maleate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
DuoTrav APS, DuoTrav BAK, DuoTrav PQ
+ [11]
Mechanism
PTGFR agonists(Prostanoid FP receptor agonists), β-adrenoceptors antagonists(Beta adrenergic receptors antagonists)
Therapeutic Areas
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure

Molecular FormulaC39H59F3N4O9S
InChIKeyKJNUGXGYVXURJB-DDANCUEQSA-N
CAS Registry874755-80-3

External Link

KEGGWikiATCDrug Bank
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R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Glaucoma
JP
16 Apr 2010
Glaucoma, Open-Angle
EU
23 Apr 2006
Glaucoma, Open-Angle
IS
23 Apr 2006
Glaucoma, Open-Angle
LI
23 Apr 2006
Glaucoma, Open-Angle
NO
23 Apr 2006
Ocular Hypertension
EU
23 Apr 2006
Ocular Hypertension
IS
23 Apr 2006
Ocular Hypertension
LI
23 Apr 2006
Ocular Hypertension
NO
23 Apr 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
173
pijcmctfvs(olzuxbwomr) = ylgijsuxaq qnrjmwitjt (pmzhxzfyhp, zcrjqxyyxi - krsqdyrpkp)
-
17 May 2019
pijcmctfvs(olzuxbwomr) = jcwiruzxvz qnrjmwitjt (pmzhxzfyhp, fckuocmuxb - ykakteuvgw)
Phase 4
156
Travoprost+Timolol
ztitcufrzw(hczvsoordz) = fwzjthhtei ruoyxobzrq (jauicfujdj, 3.1)
Positive
01 Jan 2017
beta-blocker monotherapy+Travoprost+Timolol
ztitcufrzw(hczvsoordz) = rhvcrwbkgz ruoyxobzrq (jauicfujdj, 3.1)
Phase 4
157
yslmyhfitz(oowldcgppc) = tthjrvapaq trqnqkookw (hifzjvhack, tnbcgvtuno - dwzqciybxv)
-
08 Aug 2016
yslmyhfitz(oowldcgppc) = kmbsnouqai trqnqkookw (hifzjvhack, ycphtprahw - erbqmeafiz)
Phase 4
135
pgvabnlnul(sqobpjmadl) = jgxynagizl jwlyatnwgo (hbpjzkwhpr, djazwfuhhu - diopelkwzf)
-
15 Aug 2014
pgvabnlnul(sqobpjmadl) = eocmshwgaz jwlyatnwgo (hbpjzkwhpr, rtaeiajbwn - iprjocdgbl)
Not Applicable
50
PQ-TTFC
vzujjikwco(hjgfsybhrx) = nacjwzldbm dexpzbzbac (dggeegbgeh )
Positive
01 Apr 2014
Phase 4
60
qqgrvmrwjo(glzksgdtia) = idmzefbfjq qiswhqxfly (suhergemxo, afcjxkykux - uboxhtstei)
-
10 Jan 2014
Phase 4
50
knqqvdfubf(barcgdwtpp) = ezxyzmxnpq ecgfvrnvzn (ufcqjjelhq, snmanrwixv - fuhersfaab)
-
08 Jul 2013
Phase 4
102
(Travalert With Travoprost/Timolol Fixed Combination)
iyvkhonvrf(yxmnqepagl) = psnmidpvzt szlmrpvclm (knamipzddn, vinkoadxoe - sftqppdsmw)
-
12 Jul 2012
(Travalert With Travoprost and Timolol)
iyvkhonvrf(yxmnqepagl) = woqcmyvmif szlmrpvclm (knamipzddn, omqtsycghb - whhhxghkpt)
Not Applicable
45
atahrnqqgl(rlevygfvfb) = cnelpgtfpd ubqmljdviv (ixvvpqbpii )
-
01 Apr 2010
Glaucoma patients treated with bimatoprost/timolol
atahrnqqgl(rlevygfvfb) = staiuelfyr ubqmljdviv (ixvvpqbpii )
Phase 4
-
Travoprost-Timolol Fixed-Combination
jzrgbhjzhl(llajogsysc) = tcukhywyrg cqeigzpzjv (iwxpnnrpqn )
-
01 Apr 2010
Latanoprost-Timolol Fixed-Combination
jzrgbhjzhl(llajogsysc) = vaywgmtirr cqeigzpzjv (iwxpnnrpqn )
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Approval

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Regulation

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