Drug Type Small molecule drug |
Synonyms 罗拉匹坦(前药)/帕洛诺司琼 + [2] |
Target |
Mechanism 5-HT3A receptor antagonists(5-HT 3a receptor antagonists), NK1R antagonists(Neurokinin 1 receptor antagonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhaseNDA/BLA |
First Approval Date- |
Regulation- |
Molecular FormulaC27H29F6N2O8P |
InChIKeyPKXQGSOAMISYFP-LJXNEXSDSA-N |
CAS Registry2573694-38-7 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Chemotherapy-induced nausea and vomiting | NDA/BLA | CN | 14 Dec 2023 | |
Malignant Solid Neoplasm | Phase 3 | CN | 21 Sep 2022 | |
Nausea | Phase 3 | CN | 21 Sep 2022 | |
Nausea and vomiting | Phase 3 | CN | 21 Sep 2022 | |
Vomiting | Phase 3 | CN | 21 Sep 2022 |
Phase 3 | - | HR20013+DEX (Cycle 1) | (lfowowkzrz) = khxhyifgzu igplwlbzzd (efshjelxuz ) Met View more | Non-inferior | 08 Sep 2024 | ||
FAPR+PALO+DEX (Cycle 1) | (lfowowkzrz) = fhkblrlnbq igplwlbzzd (efshjelxuz ) Met View more | ||||||
Phase 3 | 750 | HR20013+地塞米松 | zfqfayspdd(kuusrpwuaq) = opxmklbsog czfisutycl (vmkdpvhyfp ) View more | Positive | 08 Jul 2024 | ||
福沙匹坦+帕洛诺司琼+地塞米松 | zfqfayspdd(kuusrpwuaq) = gqtbiizxxf czfisutycl (vmkdpvhyfp ) View more |