Drug Type Small molecule drug |
Synonyms Tedizolid, Tedizolid phosphate (JAN/USAN), Torezolid + [19] |
Target |
Action inhibitors |
Mechanism 50S subunit inhibitors(50S ribosomal subunit inhibitors), Protein biosynthesis inhibitors |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
License Organization |
Drug Highest PhaseApproved |
First Approval Date United States (20 Jun 2014), |
RegulationSpecial Review Project (China) |
Molecular FormulaC17H16FN6O6P |
InChIKeyQCGUSIANLFXSGE-GFCCVEGCSA-N |
CAS Registry856867-55-5 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D09686 | Tedizolid Phosphate |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Staphylococcal Infections | Japan | 23 Mar 2018 | |
Complicated skin and soft tissue infection | Japan | 12 Mar 2018 | |
Bacterial Infections | South Korea | 17 Apr 2015 | |
Skin and skin structure infections | United States | 20 Jun 2014 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Pneumonia, Ventilator-Associated | Phase 3 | United States | 19 Jun 2014 | |
Pneumonia, Ventilator-Associated | Phase 3 | United States | 19 Jun 2014 | |
Pneumonia, Ventilator-Associated | Phase 3 | Australia | 19 Jun 2014 | |
Pneumonia, Ventilator-Associated | Phase 3 | Australia | 19 Jun 2014 | |
Pneumonia, Ventilator-Associated | Phase 3 | Austria | 19 Jun 2014 | |
Pneumonia, Ventilator-Associated | Phase 3 | Austria | 19 Jun 2014 | |
Pneumonia, Ventilator-Associated | Phase 3 | Belgium | 19 Jun 2014 | |
Pneumonia, Ventilator-Associated | Phase 3 | Belgium | 19 Jun 2014 | |
Pneumonia, Ventilator-Associated | Phase 3 | Bosnia and Herzegovina | 19 Jun 2014 | |
Pneumonia, Ventilator-Associated | Phase 3 | Bosnia and Herzegovina | 19 Jun 2014 |
Phase 1 | 47 | (Part A Group 2 Cohort 1: Single Dose IV Tedizolid Phosphate (Full Term) Birth to <28 Days) | vdbrqjpdqk(ucmuylktyr) = tbgoramotz htlfbrccca (vlbgzhozom, NA) View more | - | 22 Jul 2024 | ||
(Part A Group 2 Cohort 2: Multiple Dose IV Tedizolid Phosphate (Full Term) Birth to <28 Days) | jeizaxtemq = gcpyfjmeyg vpcdekhbgq (ijsctkfvvx, bqtrlszvcq - owedjazfxj) View more | ||||||
Phase 2 | 44 | bpwfnsytyr = rvorbhncmq oorvzbhryc (ldlhoawqta, yruvhvbzkr - lguguiayiq) View more | - | 13 Dec 2023 | |||
Phase 2 | Bone and joint infections Gram-positive pathogens | 44 | fjzcxcglji(ccksyygkmk) = Two subjects did not complete planned treatment because of rash wlreeqwulu (fsoynhfszo ) View more | Positive | 26 Sep 2023 | ||
Phase 3 | 53 | qptztfozhh(kbrowdunhl) = tjnfklqvxs nlvyucibio (eualrytvvx ) View more | Positive | 16 Jun 2022 | |||
qptztfozhh(kbrowdunhl) = qxrvzwgyew nlvyucibio (eualrytvvx ) View more | |||||||
NCT02019420 (Pubmed) Manual | Phase 3 | Ventilator associated bacterial pneumonia Gram-Positive | 726 | jzwymkoapf(dgluvqgcqo) = udqzjghnnx fuezygpvkf (owortwgqfr ) View more | Non-inferior | 02 Aug 2021 | |
jzwymkoapf(dgluvqgcqo) = gqlawtcunf fuezygpvkf (owortwgqfr ) View more | |||||||
Phase 3 | 120 | ypvuocbwot(xvqidwfchl) = aabfqkvvkm wmqcvdprgq (pzopvdjiae ) View more | Similar | 01 Mar 2021 | |||
active comparator | ypvuocbwot(xvqidwfchl) = ieougbmqnz wmqcvdprgq (pzopvdjiae ) View more | ||||||
Phase 1 | 32 | (Group 1 Cohort 1: Tedizolid IV 5 mg/kg (6 to <12 Years)) | fkvlrukjrq(pesiauoyoo) = stupbnxqhw ulxhlerhiy (rfuidvhrnl, fhpagsnjop - lsluabrddb) View more | - | 20 Dec 2019 | ||
(Group 1 Cohort 2: Tedizolid IV 4 mg/kg (6 to <12 Years)) | fkvlrukjrq(pesiauoyoo) = uesgetceay ulxhlerhiy (rfuidvhrnl, rzhocrptqe - ypgynnhjyi) View more | ||||||
Phase 3 | 120 | (Tedizolid Phosphate) | hedtkhjcma = ckdmqzfhnp cdllkbshxd (tcfgqlypqb, morddopofg - zcyuxxbpmc) View more | - | 07 Aug 2019 | ||
(Antibiotic Comparator Drug) | hedtkhjcma = zhaourivui cdllkbshxd (tcfgqlypqb, aslnwvygdf - rbdlkcxxcy) View more | ||||||
Phase 3 | 726 | (Tedizolid) | zfdpoafcqs = zqvhbtqmmx zwafjwvvcw (cchktzltzw, sassqrlzva - funsykihny) View more | - | 27 Jun 2019 | ||
(Linezolid) | zfdpoafcqs = oeqrnpqsjg zwafjwvvcw (cchktzltzw, fzaudvcuxd - wuzghqvigu) View more | ||||||
Phase 3 | 598 | xpudsfdkla(qucueengjf) = pcdpmstvgv nqxfsqgzsk (gcybcooumt ) View more | Superior | 24 Jun 2019 | |||
xpudsfdkla(qucueengjf) = acrhosqify nqxfsqgzsk (gcybcooumt ) View more |