Last update 21 Nov 2024

Aztreonam

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Aztreonam (JP17/USP/INN)
+ [7]
Target
Mechanism
PBPs inhibitors(Bacterial penicillin-binding protein inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
RegulationOrphan Drug (US)
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Structure

Molecular FormulaC13H17N5O8S2
InChIKeyWZPBZJONDBGPKJ-VEHQQRBSSA-N
CAS Registry78110-38-0

External Link

KEGGWikiATCDrug Bank
D00240Aztreonam

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Abdominal Abscess
JP
12 Jan 1987
Cholecystitis
JP
12 Jan 1987
Cystitis
JP
12 Jan 1987
Hemorrhagic Septicemia
JP
12 Jan 1987
Keratitis
JP
12 Jan 1987
Lung Abscess
JP
12 Jan 1987
Otitis Media
JP
12 Jan 1987
Peritonitis
JP
12 Jan 1987
Pneumonia
JP
12 Jan 1987
Prostatitis
JP
12 Jan 1987
Pyelonephritis
JP
12 Jan 1987
Sinusitis
JP
12 Jan 1987
Urethritis
JP
12 Jan 1987
Uterine Cervicitis
JP
12 Jan 1987
Abscess
US
31 Dec 1986
Gynecological infection
US
31 Dec 1986
Lower Respiratory Tract Infections
US
31 Dec 1986
Sepsis
US
31 Dec 1986
Skin and skin structure infections
US
31 Dec 1986
Urinary Tract Infections
US
31 Dec 1986
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Gram-Negative Bacterial InfectionsPhase 3
RU
05 Apr 2018
Gram-Negative Bacterial InfectionsPhase 3
ZA
05 Apr 2018
Gram-Negative Bacterial InfectionsPhase 3
HU
05 Apr 2018
Gram-Negative Bacterial InfectionsPhase 3
KR
05 Apr 2018
Gram-Negative Bacterial InfectionsPhase 3
GR
05 Apr 2018
Gram-Negative Bacterial InfectionsPhase 3
GR
05 Apr 2018
Gram-Negative Bacterial InfectionsPhase 3
HU
05 Apr 2018
Gram-Negative Bacterial InfectionsPhase 3
TH
05 Apr 2018
Complicated skin and skin structure infectionPreclinical-01 Nov 2002
Skin Diseases, InfectiousPreclinical-01 Nov 2002
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
19
Aztreonam+Ceftazidime+Avibactam
(vuxtsbkqjz) = jvicyemjmk xruiqvgtba (jbswxbbaub )
Positive
17 Nov 2022
Phase 2/3
32
kqkvkypsjk(jsokcsurmk) = tkwmlvppxy ynsuprnajq (wfzwmlezsy, qbchkqnvys - phgxzbanwf)
-
06 Jan 2022
Phase 4
5
lnxertfcdk(hbknfguwdq) = jzboxlpbve rwaitkmoez (gtsrgaitfa, nrjkxaqndl - vfskhpcpny)
-
30 Jul 2021
Phase 2
5
Nasal Placebo+Oral Aztreonam
(Standard Therapy)
eyjswjnfwb(ozackwljvb) = ywlinmcpcu dkeqifitda (mcphnumvfr, haytgcfzku - plhxynscpl)
-
12 Jan 2021
(Study Therapy)
eyjswjnfwb(ozackwljvb) = uomwxpvilf dkeqifitda (mcphnumvfr, ntdliqyxko - jljjtxikik)
Phase 2/3
32
pppigfmcbr(jkvhphnpnr) = knhyvuoykb rxqlgdmnff (erbtjlrijx )
-
16 Dec 2020
Phase 3
120
djxendpafh(jeazdwjcyo) = ghmjikfflx tjrawyarbk (xccalfzljg, wklyyemcws - jvnlyrjmqz)
-
07 Aug 2019
Antibiotic comparator+Aztreonam+Metronidazole
(Antibiotic Comparator Drug)
djxendpafh(jeazdwjcyo) = axdvwjyglt tjrawyarbk (xccalfzljg, ltldbwpxlv - djlulerqkn)
Phase 4
563
(Cipro-susceptible)
grcsweyuqm(cvvoeklkzo) = skkpsrrnmq slrsndaxcn (zmqovkiemb, yyrbikeakb - wpgvhhwxnd)
-
25 Jun 2019
grcsweyuqm(cvvoeklkzo) = kliyvyuoom slrsndaxcn (zmqovkiemb, gyoubrvcqn - znmmraxdyg)
Phase 3
802
(Ceftaroline)
kfuwysxydn(dlhdbeacsf) = woueqmlfqx nkpajxrleb (ysbgmjlglo, pccxvksnau - qgksajeydh)
-
09 Nov 2015
(Vancomycin/Aztreonam)
kfuwysxydn(dlhdbeacsf) = laftpdfsox nkpajxrleb (ysbgmjlglo, ttreeaqrnd - qlizfuprsj)
Phase 2
105
vnwalmmvxi(xqcmxvklzu) = uaemzfhqmn wncvbexrky (feqqczmrvn )
-
01 Jan 2015
Not Applicable
67
jbvgxdxkxv(amacprqlag) = 6 patients developed clinical CDAD hakwiyhent (bnrezacare )
Positive
01 Feb 2012
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