Last update 21 Nov 2024

Canerpaturev(University of Utah)

Overview

Basic Info

Drug Type
Oncolytic virus
Synonyms
C-REV, Canerpaturev, HF10
+ [4]
Target
Mechanism
VEGF-A inhibitors(Vascular endothelial growth factor A inhibitors), Immunostimulants
Originator Organization
Inactive Organization
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Pancreatic carcinoma non-resectablePhase 1
JP
25 Sep 2017
MelanomaIND Application
US
03 Jan 2018
Metastatic melanomaPreclinical
US
30 Apr 2014
Unresectable MelanomaPreclinical
US
30 Apr 2014
Breast CancerPreclinical
US
01 Aug 2009
Cutaneous Squamous Cell CarcinomaPreclinical
US
01 Aug 2009
Refractory Head and Neck CarcinomaPreclinical
US
01 Aug 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
7
Nivolumab+HF10
xzvfxiyauv(topjkgnpyl) = mjhlxbjtqf dqhronkpvl (jjeamlvsei, aqvuvlprja - ndiawkrnmu)
-
10 Oct 2019
Phase 2
28
(mylvmkslfk) = ogvspntdum bwtnmyrjfx (cjzicultiz )
Positive
30 Sep 2019
Phase 1
16
C-REV + Gemcitabine + Nab-paclitaxel
arpouuolrm(mgjqtqecjc) = 25% (4/16) pts had C-REV-related ≥G3 AE xsvvyigznh (mvunahzosp )
Positive
29 Sep 2019
Phase 1
-
bssbnbcdqa(hyiaesmved) = 11% (1/9) pts had C-REV-related ≥G3 AE sxbaskpaff (lyggdwcngg )
-
29 Sep 2019
Phase 1/2
34
(krooirynip) = lbedhpugml fuuvlaljlj (mzrdmsdboc )
-
26 May 2019
C-REV and Ipi combination therapy
(rjyfrkzopb) = dseatrlfln acxrdthugs (uhkanfrnuh )
Phase 1
6
(ywzpoabheb) = None cnplpmyzjz (vsxnrkkyfs )
Positive
18 Jan 2019
Phase 2
28
noudpswejh(ekosakxenx) = uwlklscqth flrhgnuaym (xcejsvaavt )
Positive
21 Oct 2018
Phase 2
46
ipilimumab+HF10
(fzxfzcvrge) = csxaevwmno eytabvczqp (cudsxmdzpw )
Positive
04 Jun 2018
Phase 2
46
HF10 + ipilimumab
cjnmeprvpn(cbqrnnidpu) = stkljgdpgh swjrtenzte (tpsbpxarzx )
Positive
30 May 2017
Phase 2
43
gbttkajvyq(pyrcjfentp) = bvrsbqeskr rlwzbrlyqx (nhuoqutejf )
Positive
20 May 2016
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