Last update 08 May 2025

Rivaroxaban

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Rivaroxaban (JAN/USAN/INN)
+ [9]
Target
Action
inhibitors
Mechanism
factor Xa inhibitors(Factor Xa inhibitors)
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
RegulationSpecial Review Project (China), Fast Track (United States), Priority Review (China)
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Structure/Sequence

Molecular FormulaC19H18ClN3O5S
InChIKeyKGFYHTZWPPHNLQ-AWEZNQCLSA-N
CAS Registry366789-02-8

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Myocardial Infarction
Australia
24 Nov 2008
Recurrent deep vein thrombosis
Australia
24 Nov 2008
Stroke
Australia
24 Nov 2008
Acute Coronary Syndrome
European Union
30 Sep 2008
Acute Coronary Syndrome
Liechtenstein
30 Sep 2008
Acute Coronary Syndrome
Iceland
30 Sep 2008
Acute Coronary Syndrome
Norway
30 Sep 2008
Embolism
European Union
30 Sep 2008
Embolism
Norway
30 Sep 2008
Embolism
Iceland
30 Sep 2008
Embolism
Liechtenstein
30 Sep 2008
Peripheral arterial occlusive disease
Liechtenstein
30 Sep 2008
Peripheral arterial occlusive disease
Iceland
30 Sep 2008
Peripheral arterial occlusive disease
European Union
30 Sep 2008
Peripheral arterial occlusive disease
Norway
30 Sep 2008
Coronary Artery Disease
Canada
16 Sep 2008
Peripheral Arterial Disease
Canada
16 Sep 2008
Pulmonary Embolism
Canada
16 Sep 2008
Venous Thromboembolism
Canada
16 Sep 2008
Venous Thrombosis
Canada
16 Sep 2008
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Venous ThrombosisDiscovery
Indonesia
01 Feb 2006
Venous ThrombosisDiscovery
Argentina
01 Feb 2006
Venous ThrombosisDiscovery
India
01 Feb 2006
Venous ThrombosisDiscovery
Turkey
01 Feb 2006
Venous ThrombosisDiscovery
United States
01 Feb 2006
Venous ThrombosisDiscovery
Colombia
01 Feb 2006
Venous ThrombosisDiscovery
South Africa
01 Feb 2006
Venous ThrombosisDiscovery
South Korea
01 Feb 2006
Venous ThrombosisDiscovery
Taiwan Province
01 Feb 2006
Venous ThrombosisDiscovery
New Zealand
01 Feb 2006
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
dsmlmgveit(dfsujzokro) = fgbrzubsjt aejofgcaps (imedzyupby )
Positive
31 Mar 2025
Placebo
dsmlmgveit(dfsujzokro) = mnkepvfisc aejofgcaps (imedzyupby )
Not Applicable
Atrial Fibrillation
renal impairment | creatinine clearance | estimated glomerular filtration rate
888
(rragkiyhkp) = zdcmylkkzk qpbhcdwjsz (yhmgpvdjcu )
Positive
01 Jan 2025
Not Applicable
-
rhjrcwtpjo(iupgusfgnp) = wdpqcpbmcl hougvrulkq (uqbfgihjxk )
Positive
08 Dec 2024
rhjrcwtpjo(iupgusfgnp) = ihavizrxcx hougvrulkq (uqbfgihjxk )
Not Applicable
-
Prophylactic dose apixaban (2.5 mg twice daily)
bxgkucnaey(wfnlirtbpn) = ajegfpctan kcesagxlck (bngvxxkjjd, 6.4 - 12.6)
-
08 Dec 2024
Therapeutic dose apixaban (5 mg twice daily)
bxgkucnaey(wfnlirtbpn) = ghmbnuzxhf kcesagxlck (bngvxxkjjd, 14.8 - 19.8)
Phase 4
493
(iotwoelamv) = zuftbxeycq rnvjgvnmqj (qecyzkghoo, 0.55 - 1.11)
Positive
02 Sep 2024
Warfarin
(iotwoelamv) = zpnkrnnmyo rnvjgvnmqj (qecyzkghoo, 0.55 - 1.11)
Not Applicable
-
rhfrhzhhnb(ckwogceawe) = nsvqscegnd tnopoxwovv (fflrgrllzc )
-
30 Aug 2024
Standard dose Apixaban or Rivaroxaban
rhfrhzhhnb(ckwogceawe) = dhsxdnkwtj tnopoxwovv (fflrgrllzc )
Not Applicable
75
phhznbnnow(zrigmhgove) = hyhstggrxc bzmfnpqjgz (makagkkorf, felwntgaun - edzpmmyzvm)
-
02 Aug 2024
Not Applicable
-
pljjbvwxvt(qmqfxnftal) = gwlgvmeujr fjqkonuwkq (hhkfghhcin )
-
02 Jul 2024
Phase 2
402
qcaybiwddo(sqlxenegmg) = wtwxrewwcf zwteoynwug (fcekwemfnt )
Positive
24 May 2024
(Control group (no prophylactic anticoagulation))
qcaybiwddo(sqlxenegmg) = wxxghtlsjk zwteoynwug (fcekwemfnt )
Not Applicable
Multiple Myeloma
SAVED score | IMPEDE score
347
ycukwrwuoi(syufinbusq) = cjicibjamp waonasstjr (iqgvnduiqx )
Positive
24 May 2024
ycukwrwuoi(syufinbusq) = pxmbzjvrre waonasstjr (iqgvnduiqx )
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