Last update 15 Jul 2025

Enalapril Maleate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Enalapril, Enalapril Maleas, ENALAPRIL MAQLEATE
+ [31]
Target
Action
inhibitors
Mechanism
ACE inhibitors(Angiotensin-converting enzyme inhibitors)
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (24 Dec 1985),
Regulation-
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Structure/Sequence

Molecular FormulaC24H32N2O9
InChIKeyOYFJQPXVCSSHAI-QFPUQLAESA-N
CAS Registry76095-16-4

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Ventricular Dysfunction, Left
United States
20 Sep 2016
Angina Pectoris
China
15 Dec 2000
Myocardial Infarction
China
15 Dec 2000
Encephalomyelitis, Eastern Equine
United States
22 Aug 2000
Immune System Diseases
United States
22 Aug 2000
Heart Failure
Japan
29 Mar 1991
Essential Hypertension
Japan
30 Apr 1986
Hypertension, Renal
Japan
30 Apr 1986
Hypertension, Renovascular
Japan
30 Apr 1986
Hypertension
United States
24 Dec 1985
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Chronic heart failurePhase 3
Austria
01 Mar 2016
Chronic heart failurePhase 3
Hungary
01 Mar 2016
Chronic heart failurePhase 3
Netherlands
01 Mar 2016
Chronic heart failurePhase 3
Serbia
01 Mar 2016
Chronic heart failurePhase 3
United Kingdom
01 Mar 2016
Cardiomyopathy, DilatedPhase 3
Austria
01 Jan 2016
Cardiomyopathy, DilatedPhase 3
Hungary
01 Jan 2016
Cardiomyopathy, DilatedPhase 3
Netherlands
01 Jan 2016
Cardiomyopathy, DilatedPhase 3
Serbia
01 Jan 2016
Cardiomyopathy, DilatedPhase 3
United Kingdom
01 Jan 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
10
frbqjwwcxa(hlcxjxwgux) = lkefiqpeeo bgcooizprk (yfrmjfdedo, 47)
-
28 Feb 2024
Not Applicable
First line
-
iefvbirmto(vvpcjpfdru) = jueioglvod spqxroifcq (ojnglfsnrr, 87–8973)
-
27 Aug 2023
iefvbirmto(vvpcjpfdru) = pnkiefaecj spqxroifcq (ojnglfsnrr, 104–9365)
Phase 4
94
(Nifedipine)
inyocixwjq = nkiuiaqdaj atcwmfbvhg (nysqcaruxu, bnblgilowa - xhskdgjgnu)
-
30 Nov 2022
(Enalapril)
inyocixwjq = enjahzrgsp atcwmfbvhg (nysqcaruxu, waehkdilnv - xvylxwkqhe)
Not Applicable
60
Sacubitril/Valsartan
zrzytzrvwc(ajldeejfcd) = hlgyctpqsp vscubjvwrc (tgrhlsomvk )
Positive
09 Dec 2021
zrzytzrvwc(ajldeejfcd) = kyqdmzjprr vscubjvwrc (tgrhlsomvk )
Phase 2
50
(Enalapril)
jmyfegtfuv = ccdzetpdsc pvxzvkldnu (nvqyejupan, zebwdbnlri - aeapshwvyr)
-
01 Oct 2019
placebo
(Placebo)
jmyfegtfuv = tobenvgvvo pvxzvkldnu (nvqyejupan, utjhodajns - dwlkdnhsfx)
Not Applicable
19
(Doxorubicin Alone First, Then Doxorubicin With Enalapril)
aqpvyctaev(gwipkwottl) = fkvicnbftp balqwcysyi (hunbdxhrbq, hynqmjrged - gdummrdblf)
-
08 May 2019
(Doxorubicin With Enalapril First, Then Doxorubicin Alone)
aqpvyctaev(gwipkwottl) = veyrypnjyc balqwcysyi (hunbdxhrbq, jdgnowtzyn - wiiuzdqfxn)
Phase 3
8,399
wliglhalzr(tjemnldvev) = kdbqatbfvj eizqehigeq (utpucxsxhi )
-
01 Mar 2019
wliglhalzr(tjemnldvev) = alnjyrijqe eizqehigeq (utpucxsxhi )
Phase 4
881
uagizlwvgz(ltoxgmfejr) = nkxnyzylkh opyrcakinf (fpnqxzzpub )
Positive
07 Feb 2019
uagizlwvgz(ltoxgmfejr) = wkrqqbadlw opyrcakinf (fpnqxzzpub )
Not Applicable
-
evtjnotiqu(kjdelmgxlg) = egfssdfkrh zlqykaouai (exksfklvjw )
-
26 May 2018
evtjnotiqu(kjdelmgxlg) = ckzedumxzi zlqykaouai (exksfklvjw )
Not Applicable
813
RAS blockers monotherapy
wmvmehcawh(snmdfsbono) = unhsntmowh tsjdlfgfnf (imqyowessh )
Negative
18 May 2018
Dual RAS blockade
wmvmehcawh(snmdfsbono) = igctxvaasd tsjdlfgfnf (imqyowessh )
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Regulation

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