Last update 12 Nov 2024

Vesatolimod

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Vesatolimod (USAN/INN), GS-9620, O8M467C50G
Target
Mechanism
TLR7 agonists(Toll like receptor 7 agonists)
Originator Organization
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure

Molecular FormulaC22H30N6O2
InChIKeyVFOKSTCIRGDTBR-UHFFFAOYSA-N
CAS Registry1228585-88-3

External Link

KEGGWikiATCDrug Bank
D11003Vesatolimod-

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HIV InfectionsPhase 2
ZA
09 Jun 2022
Acquired Immunodeficiency SyndromePhase 2
ES
20 Feb 2020
HIV SeropositivityPhase 2
ES
20 Feb 2020
Hepatitis B, ChronicPhase 2
US
30 Jun 2014
Hepatitis B, ChronicPhase 2
CA
30 Jun 2014
Hepatitis B, ChronicPhase 2
IT
30 Jun 2014
Hepatitis B, ChronicPhase 2
NL
30 Jun 2014
Hepatitis B, ChronicPhase 2
NZ
30 Jun 2014
Hepatitis B, ChronicPhase 2
KR
30 Jun 2014
Hepatitis C, ChronicPhase 1
US
01 Mar 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
25
Placebo+ART
(Placebo)
fovcixtxrh(llyouyquvv) = gcbctkzaoy hmcgukffzd (yoiagpmscs, einqabbqjg - nmujckpwik)
-
21 Apr 2021
(Vesatolimod)
cqjcmjhmaf(liupmipbvm) = ydfrzwtffk elwahevhft (ugdddcvzbo, sfkoluimaj - mrjvfofevr)
Phase 2
192
Placebo+TDF
(TDF + Placebo)
mupcbztdyn(rdoweprzzm) = xqyrklwtuh uftgdgiqem (eytxrechhi, liusumxhrt - dcugelskxv)
-
18 May 2020
(TDF + Vesatolimod 1 mg)
mupcbztdyn(rdoweprzzm) = sxadphpjnx uftgdgiqem (eytxrechhi, rrvrgtdxct - zevbtaxhlj)
Phase 1
48
ARV regimen+Vesatolimod
(Vesatolimod 1 mg (Cohort 1))
rcydfwzzrp(edcwsaytdv) = vynvjnehir hfkifaekpp (gcthmllrzp, khypdoudik - ncpxporcpu)
-
21 Feb 2020
ARV regimen+Vesatolimod
(Vesatolimod 2 mg (Cohort 2))
rcydfwzzrp(edcwsaytdv) = stsriqvhmw hfkifaekpp (gcthmllrzp, jjifnhzpre - sbsrvorchf)
Not Applicable
25
doykjcazyf(zbfjhpgioy) = ldkxwqijmn otmsrdtivx (yoewvsraad )
-
01 Jan 2020
Not Applicable
48
mxtqxwxugb(nromyhazro) = obnhojylzf uxluhnvpel (fwzmkniioo )
-
01 Jan 2019
Phase 1
51
nfincjoggr(ogiuzphwrm) = mild or moderate in severity stjwzqcpwh (pkfftvmyse )
Positive
01 Jan 2015
Placebo
Not Applicable
-
xarglkhbiq(fpervnwxcw) = htlvbksfbl oqtrmktyxw (tqnqbrehqd, 0.830)
-
01 Jan 2015
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