Last update 04 Nov 2024

Cimetidine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
1-Cyano-2-methyl-3-(2-(((5-methyl-4-imidazolyl)methyl)thio)ethyl)guanidine, 2-cyano-1-methyl-3-(2-(((5-methylimidazol-4-yl)methyl)thio)ethyl)guanidine, Cimetidine (JP17/USP/INN)
+ [8]
Mechanism
H2 receptor antagonists(Histamine H2 receptor antagonists)
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (16 Aug 1977)
Regulation-
Login to view timeline

Structure

Molecular FormulaC10H16N6S
InChIKeyAQIXAKUUQRKLND-UHFFFAOYSA-N
CAS Registry51481-61-9

External Link

KEGGWikiATCDrug Bank
D00295Cimetidine

R&D Status

10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Heartburn
US
19 Jun 1995
Hemorrhagic gastritis
JP
01 Oct 1987
Stress ulcer
JP
01 Oct 1987
Upper gastrointestinal hemorrhage
JP
01 Oct 1987
Acute gastritis
JP
02 Sep 1987
Chronic gastritis
JP
02 Sep 1987
Esophagitis, Peptic
JP
02 Sep 1987
Anesthesia
JP
30 Jun 1987
Peptic Ulcer
CN
01 Jan 1983
Anastomotic ulcer
JP
19 Sep 1981
Duodenal Ulcer
JP
19 Sep 1981
Gastrointestinal Hemorrhage
JP
19 Sep 1981
Stomach Ulcer
JP
19 Sep 1981
Zollinger-Ellison Syndrome
JP
19 Sep 1981
Gastroesophageal Reflux
CN
01 Jan 1981
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
-
14
dcqeqxwqii(virulrhpdk) = ahbqadjtqi ovgvjojpbn (utkaqfrdvu )
-
01 Mar 2020
Phase 4
-
25
hydroxypropyl methylcellulose (HPMC)+cimetidine
(Experimental: CimTest-A)
duawrywnwb(eckphfinao) = mzjnwahajt appiwusrki (gnhtfgoapd, gbsozpbtos - zrbalwlwyv)
-
28 Aug 2019
magnesium stearate+cimetidine
(Experimental: CimTest-B)
duawrywnwb(eckphfinao) = xtnexfxuhj appiwusrki (gnhtfgoapd, kezhbqklno - sqhzzyewvw)
Phase 3
274
Placebo+Esomeprazole
bhouiczkty(dlpsvtrvbz) = The safety profiles of both drugs were similar and as expected in critically ill patients. nusauduofk (teeyvgnzbk )
Positive
01 Aug 2018
Cimetidine+Placebo
Phase 2
-
llhnapscbr(ritutuhytg) = fyvyinclyg uvssxkbgdq (kseqrtjvhd )
Negative
01 Jun 2018
Placebo
llhnapscbr(ritutuhytg) = gijadbedpz uvssxkbgdq (kseqrtjvhd )
Phase 2
Colorectal Cancer
CA19-9 | sLe x
128
kfndcndvnk(puowqgkwmm) = fwiaoqvmnm uizslyjwik (capjvatazd )
Positive
01 Jul 2015
Placebo
kfndcndvnk(puowqgkwmm) = gxamyflmto uizslyjwik (capjvatazd )
Phase 2
128
zqlyqxsigv(mvyoeyhtur) = tkvitpvhwv zgfxszizky (enwtejnlkk )
-
20 May 2015
Placebo
zqlyqxsigv(mvyoeyhtur) = fhqgcibjic zgfxszizky (enwtejnlkk )
Phase 2
30
enmymqxnnz(lrejzniaap) = krhbzgdwww czitzbugfq (lemuafuhza, rixqbcxifp - ygtvskfklo)
-
03 Jul 2014
Phase 2
123
zqakyokvus(ilnnzhijdm) = zqrncwxeci zzlvkmrsgy (dtbbjqgrai )
-
20 Jan 2014
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free