Last update 21 Nov 2024

Encaleret sulfate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Encaleret, Encaleret sulfate (USAN)
+ [2]
Target
Mechanism
CaSR antagonists(Calcium sensing receptor antagonists)
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationFast Track (US), Orphan Drug (EU)
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Structure

Molecular FormulaC58H70Cl2F2N2O13S
InChIKeyNOJBHZIZNPMQRT-CBASKZFISA-N
CAS Registry1214922-52-7
View All Structures (2)

External Link

KEGGWikiATCDrug Bank
D10116---

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hypercalciuric Hypocalcemia, FamilialPhase 3
US
06 Jan 2023
Hypercalciuric Hypocalcemia, FamilialPhase 3
DK
06 Jan 2023
Hypercalciuric Hypocalcemia, FamilialPhase 3
JP
06 Jan 2023
Hypercalciuric Hypocalcemia, FamilialPhase 3
FR
06 Jan 2023
Hypercalciuric Hypocalcemia, FamilialPhase 3
IT
06 Jan 2023
Hypercalciuric Hypocalcemia, FamilialPhase 3
AU
06 Jan 2023
Hypercalciuric Hypocalcemia, FamilialPhase 3
TW
06 Jan 2023
Hypercalciuric Hypocalcemia, FamilialPhase 3
CA
06 Jan 2023
Hypercalciuric Hypocalcemia, FamilialPhase 3
GB
06 Jan 2023
HYPOCALCEMIA, AUTOSOMAL DOMINANT 1Phase 3-22 Dec 2022
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
13
(pcauqnvgpw) = gunprwksgx pselciueoj (chrzqwydsq )
Positive
12 Oct 2023
Not Applicable
-
cyvezjwqxh(pgqebhgfaf) = qwwbpedler ucwntxrwbx (gjxeubjdfo )
-
04 Nov 2022
Phase 2
526
Placebo to MK-5442+Calcium carbonate+Vitamin D3
(Placebo)
yjxjzcsbpo(twslkbymzz) = qcbpmikjus dspukjpokd (ennrufbdhu, xbmzhimfqv - jdoqbaibig)
-
16 Nov 2012
Placebo to Alendronate+MK-5442+Calcium carbonate+Vitamin D3
(MK-5442 5 mg)
yjxjzcsbpo(twslkbymzz) = ngtjfbybmi dspukjpokd (ennrufbdhu, ditoyspxrb - hrjrazrigh)
Phase 2
383
Placebo+MK-5442
(MK-5442 2.5 mg)
trwidfkxwl(nnnrbwtolx) = ysejmggmtz iyoqhorlnb (kidmpviywn, xtjejknpji - nganvikaxb)
-
10 Oct 2012
Placebo+MK-5442
(MK-5442 5 mg)
trwidfkxwl(nnnrbwtolx) = mjikidnjqq iyoqhorlnb (kidmpviywn, qndkxhydvb - vdvmsiwafu)
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Regulation

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