This study investigates the time course of change in calcium in the blood after a pregnant subject takes an oral dose of calcium carbonate (commonly marketed as "Tums"). This information is important for trials investigating whether calcium can reduce postpartum hemorrhage, bleeding after delivery.

Start Date01 Jan 2025

Sponsor / Collaborator

Stanford University

NCT06580782

/ RecruitingPhase 4IIT

Calcium Carbonate to Augment Labor Contractions

The investigators think that calcium carbonate can act as an assistive medication to improve contractions during labor.

Start Date18 Nov 2024

Sponsor / Collaborator

Weill Medical College of Cornell University

NCT06352775

/ Active, not recruitingNot ApplicableIIT

The Effect of Calcium Carbonate on Labor Induction: A Pilot Study

The investigators aim to evaluate the safety and efficacy of administering calcium carbonate to laboring participants undergoing labor inductions. The investigators hypothesize that calcium carbonate is a low-risk preventative measure to decrease oxytocin induction time and dosage, decrease the rate of labor dystocia, decrease the rate of cesarean deliveries, and demonstrate no differences in maternal or neonatal safety outcomes.

Start Date01 Jun 2024

Sponsor / Collaborator

Wake Forest School of Medicine

100 Clinical Results associated with Calcium carbonate

100 Translational Medicine associated with Calcium carbonate

100 Patents (Medical) associated with Calcium carbonate

77,528

Literatures (Medical) associated with Calcium carbonate

01 Feb 2026·Lancet Child & Adolescent Health

Impact of high-dose vitamin D and calcium carbonate supplementation on bone density in adolescents living with HIV: a randomised, placebo-controlled trial

Article

Author: Mujuru, Hilda ; Ferrand, Rashida A ; Filteau, Suzanne ; Banda Mabuda, Hildah ; Dzavakwa, Nyasha V ; Kranzer, Katharina ; Chisenga, Molly ; Bandason, Tsitsi ; Simms, Victoria ; Redzo, Nicol ; Rowland-Jones, Sarah L ; Schaible, Ulrich E ; Mchugh, Grace ; Tang, Jonathan C Y ; Gregson, Celia L ; Kasonka, Lackson

BACKGROUND:

HIV has adverse impact on skeletal development in children despite antiretroviral therapy (ART). We investigated the effect of high-dose (20 000 IU) weekly vitamin D₃ and daily calcium carbonate (500 mg) supplementation for 48 weeks on bone density and muscle strength and power among peripubertal individuals (11-19 years) with perinatally acquired HIV.

METHODS:

We conducted an individually randomised, double-blind, placebo-controlled trial. Individuals taking ART for at least 6 months who had a defined caregiver, and knew their HIV status (in those aged >12 years) were recruited from HIV clinics in Harare, Zimbabwe and Lusaka, Zambia. The primary outcome was total body less-head bone mineral density (TBLH-BMD) Z score and secondary outcome was lumbar spine bone mineral apparent density (LS-BMAD) Z score (both measured by dual-energy x-ray absorptiometry). Linear regression was used to compare arms adjusting for country and baseline value of the measure. Pre-specified subgroup analyses by country, age-group, sex, pubertal stage, calcium intake, tenofovir disproxil fumarate use, and baseline vitamin D insufficiency (defined as 25[OH]D <75 nmol/L), and a post-hoc subgroup analysis by viral suppression, were performed. A Participant Advisory Board that included adolescents with HIV, their guardians, and health providers guided study conduct. The trial is registered with the Pan African Clinical Trials Registry, PACTR20200989766029.

FINDINGS:

Of 842 participants (median age 15 years [IQR 13-17], 448 [53%] female and 394 [47%] male) enrolled between Feb 4 to Nov 23, 2021, 639 (76%) were vitamin D insufficient. At 48 weeks, outcomes were available for 751 (89%) participants. There was no difference by arm in TBLH-BMD Z score (intervention vs control: mean -1·53 [SD 1·18] vs -1·56 [1·12], adjusted mean difference -0·04 [95% CI -0·01 to 0·09]) or in LS-BMAD Z score (intervention vs control: -0·64 [1·17] vs -0·71 [SD 1·16], adjusted mean difference -0·05 [95% CI -0·01 to 0·12]). However, among participants with vitamin D insufficiency at baseline, there was a significantly higher LS-BMAD Z score (adjusted mean difference 0·09 [95% CI 0·02 to 0·16], p_interaction=0·025) in the intervention arm than in the control arm. The corresponding adjusted mean difference in TBLH-BMD Z score was 0·06 (0·00-0·11), p_interaction=0·15. There was no statistical evidence of interaction in other subgroups. No drug-related severe adverse events were observed.

INTERPRETATION:

There was no difference in bone density between arms overall, but among those with vitamin D insufficiency the intervention improved bone density. High-dose vitamin D₃ and calcium supplementation, a safe and cheap intervention, during adolescence might promote bone accrual and mineralisation in those with vitamin D insufficiency, which could increase peak bone mass.

FUNDING:

European Developing Country Clinical Trials Partnership.

07 Jan 2026·ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The effect of antacid and mineral supplements on bictegravir pharmacokinetics: results from a Phase 1, open-label, drug–drug interaction study

Article

Author: Arora, Priyanka ; Ling, John ; Hindman, Jason T. ; Marathe, Dhananjay D. ; West, Steve ; Palaparthy, Ramesh

ABSTRACT:

The mechanism of action of integrase strand transfer inhibitors involves binding to magnesium ions in the active site of the HIV integrase enzyme, making them susceptible to chelation-type drug–drug interactions with metal cation–containing medications. This study evaluated the potential of metal cation–containing antacids and mineral supplements to impact bictegravir (BIC) exposure and assessed alternative approaches for combined use. This was an open-label, single-dose, Phase 1 study in adult participants without HIV. The pharmacokinetics and safety of BIC (administered as part of a single-tablet combination with emtricitabine [F] and tenofovir alafenamide [TAF; B/F/TAF]) were assessed when co-administered with maximum-strength aluminum/magnesium-containing antacid (referred to as “aluminum/magnesium-containing antacid”), calcium carbonate, or ferrous fumarate under fasted and fed conditions, and administered 2 hours before or after the antacid. Pharmacokinetic parameters were compared using analysis of variance to calculate geometric least-squares mean ratios and 90% confidence intervals. Forty-two participants were enrolled. BIC exposure (area under the plasma concentration–time curve extrapolated to infinity) was reduced by 79%, 33%, and 63%, respectively, when co-administered with aluminum/magnesium-containing antacid, calcium carbonate, and ferrous fumarate under fasted conditions. Co-administration of B/F/TAF with calcium carbonate or ferrous fumarate with a meal and administration of B/F/TAF 2 hours before the antacid reduced the impact of the interactions. B/F/TAF was well tolerated alone or in combination with metal cation–containing medications. Co-administration of BIC and calcium/iron-containing supplements with a meal and administration of BIC 2 hours or more before aluminum/magnesium-containing antacids are some of the effective strategies to mitigate chelation effects on BIC exposure. This study was registered at NCT05502341 / NCT06333808 .

02 Jan 2026·International Journal of Coal Preparation and Utilization

Characterization of solid particles with different particle sizes in high-temperature coal tar pitch

Author: Li, Gang ; Gao, Long ; Zhang, Haiyong ; Wang, Yonggang ; Yang, Jingdong ; Zhao, Yiting

High-temperature coal tar pitch (HCTP) serves as a crucial precursor for high-quality carbon materials, while solid particle (SP) characteristics significantly influence the properties of the pitch.This study explores the compositional differences of SPs across various sizes to facilitate their effective separationWe employed ultrasonic graded centrifugation to isolate seven SP types of different sizes and analyzed their properties using SEM, SEM-EDS plane scanning, laser particle size anal. (LPSA), organic element anal. (EA), FT-IR, ICP-MS, and XRD.Our results reveal distinct variations in the SP distribution by particle size.As the particle size decreases, the proportion of particles in the 1-100 μm range decreases, while ultrafine particles (0.01-0.1 μm) become more prevalent.The carbon content in SPs initially increases and then decreases with smaller particle sizes, reaching a peak in medium-sized particles.Non-carbon impurities such as Si, S, Zn, Pb, Ca, Fe, and inorganic ash are concentrated in larger particles (SP1-SP2) and smaller particles (SP6-SP7).Notable inorganic compounds like PbS, ZnS, and FeS are found across all sizes, whereas SiO₂ and CaCO₃ are restricted to larger particles (SP1-SP2).Furthermore, smaller particles exhibit greater sp. surface areas and pore volumes

News (Medical) associated with Calcium carbonate

26 Dec 2025

·www.einpresswire.com

A Chiropractor’s Perspective on Structural and Neurological Factors in Hiatal Hernia and Chronic Digestive Symptoms

Structural, breathing, posture and nervous system factors may drive hiatal hernia and chronic reflux beyond medication alone. ROCKVILLE CENTRE, NY, UNITED STATES, December 26, 2025 / EINPresswire.com / -- Hiatal hernia and chronic digestive discomfort affect a substantial portion of the adult population in the United States. Clinical research indicates that hiatal hernias are present in approximately 20 percent of adults and are identified in nearly 30 percent of individuals undergoing upper endoscopy. Digestive conditions such as reflux, gastroesophageal reflux disease, and chronic heartburn are estimated to affect between 18 and 28 percent of U.S. adults. Despite the prevalence of these symptoms, many individuals remain unaware of the structural and neurological factors that may contribute to persistent discomfort. How Hiatal Hernia Impacts the Body A hiatal hernia occurs when part of the stomach shifts upward through the diaphragm. This displacement can interfere with normal pressure regulation beneath the sternum and alter breathing mechanics. Individuals may experience symptoms such as heartburn, reflux, chest tightness, post-meal discomfort, shallow breathing, or a persistent sensation of pressure in the upper abdomen. Chronic stress patterns, restricted breathing, and postural strain may further limit diaphragm mobility, increasing mechanical stress on digestive structures. Medication Reliance and Unresolved Symptoms Many individuals experiencing reflux or chronic heartburn and are prescribed proton pump inhibitors such as Nexium or Prilosec or rely on antacids like Tums for symptom management. While these medications may offer temporary relief, prolonged reliance without addressing contributing mechanical or neurological factors often results in incomplete symptom resolution. Patients frequently report undergoing upper endoscopy procedures that confirm irritation or inflammation, yet treatment recommendations often remain limited to medication management rather than exploring physical contributors. Long-Term Considerations and Potential Complications Chronic reflux and prolonged irritation of the esophagus have been associated with conditions such as Barrett’s esophagus. This condition involves abnormal cellular changes and has been linked to an increased risk of esophageal cancer. Health professionals emphasize that unresolved irritation over time may increase the likelihood of long-term complications. Improving awareness of contributing factors may help reduce unnecessary prolonged discomfort and associated health risks. Structural and Neurological Influences on Digestive Function From a structural perspective, diaphragm mobility, spinal alignment, breathing patterns, and nervous system regulation all influence digestive function. When the diaphragm becomes overly tense or restricted, stomach position and pressure balance may be disrupted, contributing to ongoing symptoms. Some clinical discussions include supportive modalities such as cold laser therapy, chiropractic adjustments, manual viscerialmanipulation and breathwork techniques as part of broader efforts to calm irritated tissue and support neuromuscular balance. These approaches are generally viewed as complementary within a wider focus on function and mobility. Community Awareness and Clinical Perspective Dr. John Gehnrich, a chiropractor with more than 25 years in practice since 2000, specializes in working with individuals experiencing chronic digestive symptoms associated with hiatal hernia, reflux, GERD, and persistent heartburn. Through years of clinical observation and customizing solutions to this chronic disorder plaguing so many of his patients, he has noted that many people arrive after long periods of symptom management without clear explanations for why discomfort continues. Dr. Gehnrich’s work focuses on identifying the underlying mechanical and neurological contributors that are often overlooked, including diaphragm restriction, postural strain, structural misalignment, altered breathing patterns, and nervous system imbalance. He emphasizes that these factors may play a significant role in digestive function and symptom persistence and has been a big part of his success with these patients over the years In his experience, many individuals feel frustrated after relying on medication alone or undergoing diagnostic procedures that confirm irritation without addressing why the condition developed or continues. By emphasizing education and awareness, Dr. Gehnrich aims to help individuals better understand how daily habits, stress patterns, posture, chiropractic adjustments, and breathing mechanics may influence long-term digestive health. Education and Prevention Through Awareness Health professionals note that improving public understanding of structural and neurological contributors to digestive symptoms may help individuals make more informed decisions about their care. Addressing underlying contributors rather than relying solely on long-term symptom suppression may support improved comfort and help reduce the progression of chronic digestive conditions. Reference Data and Sources Hiatal hernia prevalence https://www.ncbi.nlm.nih.gov/books/NBK562200/ Hiatal hernia findings during upper endoscopy https://pubmed.ncbi.nlm.nih.gov/20381490/ GERD prevalence in the United States https://pubmed.ncbi.nlm.nih.gov/23907619/ Proton pump inhibitor safety and long-term use https://www.fda.gov/drugs/postmarket-drug-safety-information-patients-and-providers/fda-drug-safety-communication Barrett’s esophagus and cancer risk https://www.niddk.nih.gov/health-information/digestive-diseases/barretts-esophagus Diaphragm function and breathing mechanics https://pubmed.ncbi.nlm.nih.gov/29580445/ Contact Info - Rhino Chiropractic 14 Glen Cove Rd Roslyn Heights, NY 11577 516) 536-6000 www.rhinochiropractic.com Dr. John Gehnrich Rhino Chiropractic & Holistic Wellness Center +1 516-536-6000 email us here Legal Disclaimer: EIN Presswire provides this news content "as is" without warranty of any kind. We do not accept any responsibility or liability for the accuracy, content, images, videos, licenses, completeness, legality, or reliability of the information contained in this article. If you have any complaints or copyright issues related to this article, kindly contact the author above.

22 May 2025

·pharma.economictimes.indiatimes.com

Many MSME pharma firms making substandard drugs, CDSCO data shows

New Delhi: Many pharmaceutical companies in the micro, small and medium enterprise (MSME) sector are manufacturing substandard drugs , according to the data by India's drug regulator, the Central Drugs Standard Control Organisation ( CDSCO ). According to the data for April, most of these companies are making drugs that failed safety standards and have been found to be sub- standard quality. As part of the continuous regulatory surveillance , drug samples are picked from sales and distribution points and analysed at various government run laboratories. According to the drug regulatory authority, in April about 60 samples failed to meet the quality standards and have been declared as Not of Standard Quality (NSQ) Drugs . Samples which failed tests are carboxymethylcellulose sodium eye drops, an eye lubricant, also known as artificial tears, bupivacaine hydrochloride injection, a local anaesthetic, calcium carbonate and vitamin D3 tablets, among others. Interestingly, they have been manufactured at lesser known pharma companies like Gidsha Pharmaceuticals in Gujarat, Martin and Brown Biosciences in Solan, Himachal Pradesh, Sai Parenterals in Hyderabad, Nestor Pharmaceuticals, Faridabad, among others. These companies could not be contacted immediately. "This has been the trend for some time now. Most of these MSME are found to be manufacturing drugs which are not of standard quality. That is the reason the health ministry came out with a notification which outlines standards for the pharma companies," said a person with knowledge of the matter. Earlier in 2023, over 65 per cent of MSME enterprises were found to be manufacturing drugs that were not of standard quality (NSQ) during risk-based inspections (RBI) of pharma companies. "Of the total MSME units inspected, 30 per cent were issued stop production orders (SPO), while samples of 68% MSME companies have failed. This is alarming," the person said. The CDSCO and state drug inspectors have been conducting these inspections as part of a massive nationwide crackdown on spurious and substandard medicines. This followed a controversy over alleged Made-in-India cough syrups being responsible for the deaths of children in The Gambia. The CDSCO has found that these companies have issues related to infrastructure, quality management systems and product manufacturing process knowledge. "There has been a strong correlation between NSQ and the condition of manufacturing set up. Monthly NSQ data shows repeat failures for a company with the same product with multiple companies month on month," another person said. India's drug regulator had earlier pointed to an urgent need to review the current GMP regulations and Quality Management Systems being followed by pharmaceutical companies during the RBI. By Teena Thacker ,

31 Dec 2024

·pharma.economictimes.indiatimes.com

Six common medications, including antibiotics and allergy drugs, fail quality tests

Jaipur: The health department released a list of six drugs on Monday that failed quality tests and are being sold in the market. These include commonly used antibiotics such as amoxicillin and clavulanate potassium, anti-allergic medicines like levocetirizine hydrochloride and montelukast, the gastro-resistant drug pantoprazole, and cefpodoxime, which is an antibiotic drug. These drugs failed the quality test as they did not contain any of the promised medicinal content. The drugs were manufactured in Bengaluru, Punjab, Sikkim, Mohali, and Himachal Pradesh. A sample of the medicine Pregabalin, which is in a class of medications called anticonvulsants, failed the quality test as it was found to have nil content of pregabalin. The drug was manufactured by a company in Mohali. A health department official said that directions have been issued to drug control officers in districts to remain alert and take necessary action. They have been directed to collect samples of other medicines manufactured by the companies whose samples failed the quality test. The samples of amoxicillin and clavulanate potassium manufactured by a Bengaluru-based firm failed as they contained none of the promised drugs. Earlier, a report was issued by the health department in which samples of drugs in combination with nimesulide and paracetamol (pain relief), pheniramine maleate injection (to treat symptoms of allergic conditions), a combination of calcium carbonate and vitamin D3 suspension (dietary supplement for people who have bone problems or low calcium and vitamin D levels), a combination of telmisartan, amlodipine, and hydrochlorothiazide (to treat high blood pressure), a combination of telmisartan and amlodipine (for high blood pressure), a combination of levocetirizine dihydrochloride and montelukast (relieves sneezing and runny nose due to allergies), heparin sodium injection (anticoagulant), and an injection of sulphamethoxazole and trimethoprim (treats infections caused by bacteria) failed quality tests. These drugs were manufactured in Baddi, Sirmour and Solan (Himachal Pradesh), Vadodara (Gujarat), Roorkee (Uttarakhand), and Digiana (Jammu).

100 Deals associated with Calcium carbonate

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KEGG	Wiki	ATC	Drug Bank
D00932	Calcium carbonate	A12AA04 A02AC01	DB06724

R&D Status

Approved

10 top approved records.

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Indication	Country/Location	Organization	Date
Hyperphosphatemia	Japan	Mylan Seiyaku Ltd.	16 Jun 1999
Hyperphosphatemia	Japan	Pfizer Japan, Inc.	16 Jun 1999
Osteoporosis	China	Haleon (Suzhou) Pharmaceutical Co. Ltd.	-

Developing

10 top R&D records.

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Indication	Highest Phase	Country/Location	Organization	Date
Gastroesophageal Reflux	Phase 2	Japan	Otsuka Pharmaceutical Co., Ltd.	31 Oct 2017
Hyperchlorhydria	Phase 2	Japan	Otsuka Pharmaceutical Co., Ltd.	01 Aug 2014
Castration-Resistant Prostatic Cancer	Phase 1	Israel	AMORPHICAL LTD	01 Jun 2022
Advanced Malignant Solid Neoplasm	Phase 1	Israel	AMORPHICAL LTD	18 Jul 2018
Bone metastases	Phase 1	Israel	AMORPHICAL LTD	18 Jul 2018
Liver metastases	Phase 1	Israel	AMORPHICAL LTD	18 Jul 2018
Adrenocortical Carcinoma	Phase 1	Israel	AMORPHICAL LTD	25 Jun 2017
Secondary malignant neoplasm of lung	Phase 1	Israel	AMORPHICAL LTD	25 Jun 2017

Clinical Result

Indication

Phase

Evaluation

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Study	Phase	Population	Analyzed Enrollment	Group	Results	Evaluation	Publication Date


NCT02916862 (MetA-Bone, CTgov)	Phase 2	Osteoporosis	177	Soluble Corn Fiber+calcium carbonate (Soluble Corn Fiber (SCF) + Calcium)	zeuxwkirvs(cxbmhvqzdp) = njejofojle fcfjlzwdfn (adhthxnvxo, 11.8) View more	-	29 Oct 2025
				Soluble Corn Fiber (SCF) without Calcium (Soluble Corn Fiber (SCF) Without Calcium)	zeuxwkirvs(cxbmhvqzdp) = gegkreuxkh fcfjlzwdfn (adhthxnvxo, 10.5) View more
NCT02186600 (HOPS, CTgov)	Phase 3	Osteoporosis	276	Calcium Carbonate+Vitamin D3 (Control)	smlfpufumx(qptephagrj) = bewxytcwkb epqygdimcl (mrsoevxkcx, 334.7) View more	-	27 Jun 2023
				Risedronate+Calcium Carbonate+Vitamin D3 (Risedronate)	smlfpufumx(qptephagrj) = dzoqibemxj epqygdimcl (mrsoevxkcx, 292.3) View more
NCT03089216 (CTgov)	Phase 4	Dentin Sensitivity	108	Combined Bleaching(2x20) (Combined Bleaching(2x20))	dhbhucpmja(ejaebbwwtq) = mwalmnzbym xoyowxhzfq (hyhztjbrrr, ijgedinbtw - tawvwsdeic) View more	-	05 Aug 2019
				Combined Bleaching (1x20) (Combined Bleaching(1x20))	dhbhucpmja(ejaebbwwtq) = sdbnubfkwr xoyowxhzfq (hyhztjbrrr, lvorkrzvxu - qxildcbesi) View more
NCT00416715 (CTgov)	Phase 2	Breast cancer recurrent \| Arthralgia \| Musculoskeletal Abnormalities ... View more	100	vitamin D (Baseline)	avtxlmtwox = xvqfmwwuwp khdppqpwbp (rvwtvilrvh, wrhxplkjlb - zusdlxxnrm) View more	-	11 Jul 2017
				Vitamin D (Post Vitamin D Repletion (1 Month))	avtxlmtwox = zflrqbjzua khdppqpwbp (rvwtvilrvh, iuzhavzzbl - ymlrvhadxt) View more
NCT00620113 (0822-022 \| MK-0822-022, CTgov)	Phase 2	Osteoporosis, Postmenopausal	287	Placebo+Calcium carbonate+Vitamin D3 (Placebo)	srrrmzgrmr(xxcwbgjbju) = kievwsnhrw cjdbpglxod (cdwugoxcdu, mwblzntaud - ohuyugbmtm) View more	-	13 Mar 2017
				Odanacatib+Calcium carbonate+Vitamin D3 (Odanacatib 10 mg)	srrrmzgrmr(xxcwbgjbju) = orjfuwqzka cjdbpglxod (cdwugoxcdu, ktxgwcrynf - ldhidrlbds) View more
NCT00073073 (CTgov)	Phase 2	Noninfiltrating Intraductal Carcinoma \| Invasive Mammary Carcinoma	46	Vitamin D+Exemestane+Calcium carbonate	qmotuwbslx(hifvpvoehs) = xpljvxynty fboxblrjeu (ccfokwydok, eieigqwppm - shjodfbnhj) View more	-	17 May 2016
NCT00001304 (CTgov)	Phase 2	Hypoparathyroidism	27	Synthetic Human Parathyroid Hormone 1-34 (PTH 1-34)	vyphqwdaub(bepjcgujzr) = ufvixptdsd adryhmtiiu (cyxvqytnpz, 0.02) View more	-	15 Dec 2015
				calcitriol+Calcium carbonate (Calcitriol & Calcium)	nbnhwwqyot(aghmpenjzn) = dsllqcsjst tskavsolay (tamqdhjtyr, mbfwivtfuc - hujimztkjt) View more
NCT01578200 (LANDMARK, ASN2015)	Phase 3	Hodgkin's Lymphoma intact parathyroid hormone (iPTH)	2,309	Lanthanum Carbonate (LC)	vqezvnjygu(qsfaxodldw) = bxmalyhdun bvnzhqikcn (ozjgcxxmhk ) View more	Positive	03 Nov 2015
				Calcium Carbonate (CC)	vqezvnjygu(qsfaxodldw) = yjtdzsmggy bvnzhqikcn (ozjgcxxmhk ) View more
ERA2015	Phase 4	Hyperphosphatemia	102	Calcium Carbonate Emulsion (CCE)	twcswbuelu(tucjlllgqj) = CCE seems to show less forgetfulness in taking medication liirjopfpo (mktuzsasbx ) View more	Positive	21 May 2015
				Calcium Carbonate Tablets (CCT)
NCT01447433 (CTgov)	Phase 4	Obesity	53	Energy restriction+Calcium Carbonate (Calcium+D)	idjkqpwiov(rduxoquggd) = qeielfcshz bmujxqrtpz (qfmytdzpqm, 1.7) View more	-	06 Mar 2012
				Energy restriction (Control)	idjkqpwiov(rduxoquggd) = fmcesedukk bmujxqrtpz (qfmytdzpqm, 1.8) View more

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