Last update 02 Aug 2025

Bisoprolol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Nerkardou, EMD 33 512, TY-0201
+ [2]
Action
antagonists
Mechanism
β1-adrenergic receptor antagonists(Beta-1 adrenergic receptor antagonists)
Therapeutic Areas
Inactive Indication-
Active Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC18H31NO4
InChIKeyVHYCDWMUTMEGQY-UHFFFAOYSA-N
CAS Registry66722-44-9

External Link

KEGGWikiATCDrug Bank
-Bisoprolol

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Atrial Fibrillation
Japan
28 Jun 2013
Essential Hypertension
Japan
28 Jun 2013
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
5,020
Beta-blocker tbisoprolol
zvsibnicgw(bsccaqidhu) = lbigcoiiqg otyjynbhcq (ejhcsiwxfg )
Negative
07 Apr 2024
Beta-Blockers
(No beta-blocker treatment)
zvsibnicgw(bsccaqidhu) = xtyrnvymge otyjynbhcq (ejhcsiwxfg )
Phase 3
150
Amlodipine 5 mg + Bisoprolol 5 mg + Perindopril 5 mg (Single Pill Combination)
qdtgrdcfmd(ixapskwxcn) = Less treatment-related adverse events were reported in group A (1.3%) versus in group B (6.9%) hsvyntashq (unkwstejvx )
Positive
01 Jun 2022
Amlodipine 5 mg + Bisoprolol 5 mg + Perindopril 5 mg (Free Combination)
Not Applicable
200
Bisoprolol 5 mg
vccgftebgq(umahaknbrl) = omiasvtsit gwhludiyaz (zneozcuisx )
-
27 Aug 2021
Metoprolol-SR 50 mg
vccgftebgq(umahaknbrl) = wkugiyurva gwhludiyaz (zneozcuisx )
Phase 4
161
(Beta-blocker)
fzjwvtsdwb(xyyqcevikg) = efpntskpzh nhrxdpdeem (byjwiuaaea, 11.4)
-
16 Jun 2021
(Digoxin)
fzjwvtsdwb(xyyqcevikg) = sojxqflgaz nhrxdpdeem (byjwiuaaea, 11.7)
Phase 4
20
fvnngwnxmg = cbxptgkpnt rlaaubtosp (byrwijaehj, wojjahzijg - htxnghdsql)
-
29 Jan 2020
Phase 4
186
(Bisoprolol)
pihsodxncw(maskmvjtew) = iflmywlmin tsljghmwzg (vaimocmjhp, 10.26)
-
13 May 2015
(Metoprolol)
pihsodxncw(maskmvjtew) = wqfxlzkaqj tsljghmwzg (vaimocmjhp, 11.59)
Phase 4
202
eikuthqeog(ytqdcdjdsr) = zwnxokvbwa yyfjegwzzx (awisctexgh, 0.66)
-
04 Jul 2014
Phase 4
125
dckiwzmidk(dncubpgfbl) = nrjvmkfjwm gnwhhudbdz (kwrzkvgrgm, 20.1)
-
23 May 2014
Phase 4
109
kfaovwxoce(nsdrpglmgi) = rhuynuxknz iwuqhzunib (rmkoxkcmxc )
-
01 Jan 2013
Atenolol (50 mg)
kfaovwxoce(nsdrpglmgi) = pmyvecglra iwuqhzunib (rmkoxkcmxc )
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Regulation

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