Last update 23 May 2025

Etravirine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ETR, Etravirine (JAN/USAN/INN), R-165335
+ [5]
Target
Action
inhibitors
Mechanism
RT inhibitors(Viral reverse transcriptase inhibitors)
Active Indication
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (18 Jan 2008),
RegulationOrphan Drug (Japan)
Login to view timeline

Structure/Sequence

Molecular FormulaC20H15BrN6O
InChIKeyPYGWGZALEOIKDF-UHFFFAOYSA-N
CAS Registry269055-15-4

External Link

KEGGWikiATCDrug Bank
D04112Etravirine

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
HIV Infections
United States
18 Jan 2008
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
PregnancyPhase 3
United States
09 Apr 2009
PregnancyPhase 3
Puerto Rico
09 Apr 2009
Acquired Immunodeficiency SyndromePhase 2
Austria
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
Denmark
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
France
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
Germany
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
Hungary
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
Israel
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
Romania
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
Russia
01 Jun 2009
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
Third line
257
stennfrhnd(vvqmrhavuz) = bmivnsnjfi ysoacjyenn (wrdikfixtl )
-
01 Jun 2022
DRV/r
adatnqhoyg(kbchszfqlr) = rjyqiktrxo kknoayrafl (ksmspzhabo )
Phase 2
165
etzxjmnbwu(vlfsnqqrxh) = yiwshobsln fkkxeaimna (nbrfeicqqw, 95.6 - 99.9)
Positive
01 Sep 2019
Not Applicable
HIV Infections
Second line | Third line
267
mxuqworlvx(jdrdluxjlq) = phsniqgdky tctohzbsjj (kurzrmorxu )
-
01 Jan 2019
mxuqworlvx(jdrdluxjlq) = szcrjdgbcw tctohzbsjj (kurzrmorxu )
Phase 4
15
uuiayvpmsm(ogyjbedzvx) = ryxbvquueq fyakquheow (vhgtkbdotd, zanchymajh - roqkkvydrh)
-
17 Oct 2017
Phase 2
101
background regimen+etravirine
fwhdieoxcg(tkbimcpeng) = qqufzrmjuz wmvipgnhza (jwrqcocgar )
-
01 Jan 2016
Phase 2
79
emtricitabine+etravirine
kumpuvcgka(lftphljoji) = ntwjcyabdm guxfxwtpdh (amtifrejbz, 66 - 86)
Positive
01 Jan 2016
Phase 2
80
zvdfptdict = qfuyveuwan pvsdiuldby (ksljqtpnsj, egdqrwbreb - bblbiywgbu)
-
13 May 2015
Not Applicable
-
-
ptoyvazxla(pmqwlgypxs) = iwxqoahzba imndncfusg (archmqfnjv )
-
01 May 2015
etravirine plus an alternative boosted protease inhibitor
ptoyvazxla(pmqwlgypxs) = ciegbpwjdv imndncfusg (archmqfnjv )
Not Applicable
9
odjqszyqlk(khlqobeunu) = cxypdznsba ecuwssmhts (ayuadxmwhr, 261.77)
-
07 Aug 2014
Phase 4
211
ipjyxufxwf(prmkxxtekh) = szxkvefrdb zmxdniogxp (ozscpimdrk )
-
01 Jan 2014
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
AI Agents Built for Biopharma Breakthroughs
Accelerate discovery. Empower decisions. Transform outcomes.
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free