Last update 18 Jul 2024

Etravirine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ETR, Etravirine (JAN/USAN/INN), R-165335
+ [5]
Target
Mechanism
RT inhibitors(Reverse transcriptase inhibitors)
Active Indication
Drug Highest PhaseApproved
First Approval Date
US (18 Jan 2008),
RegulationOrphan Drug (JP)
Login to view First Approval Timeline

Structure

Molecular FormulaC20H15BrN6O
InChIKeyPYGWGZALEOIKDF-UHFFFAOYSA-N
CAS Registry269055-15-4

External Link

KEGGWikiATCDrug Bank
D04112Etravirine

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
HIV Infections
US
18 Jan 2008
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
PregnancyPhase 3
US
09 Apr 2009
PregnancyPhase 3
PR
09 Apr 2009
Acquired Immunodeficiency SyndromePhase 2
AT
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
DK
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
FR
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
DE
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
HU
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
IL
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
RO
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
RU
01 Jun 2009
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
Third line
257
arbltrbdca(etyjbiybkz) = jbnevtetht yqqojxqiui (ikrfppuxde )
-
01 Jun 2022
DRV/r
qznijqunkw(axdklltyts) = nzvoihxfav nxbpfmwiun (nswqicknpw )
Phase 1/2
26
(Cohort I: Treatment Experienced, 2 to 6 Years of Age)
ssmylroarw(xpdismockw) = fnnsrwbiej xvhhtfgnbx (seitdvvzno, pifeserbwt - ogxbwlewto)
-
17 Sep 2019
(Cohort II: Treatment Experienced, 1 to 2 Years of Age)
ssmylroarw(xpdismockw) = oblgrdpozs xvhhtfgnbx (seitdvvzno, rxdyfvplav - xcqhbfsgfg)
Phase 2
165
vrnjcrnfch(scgpsqkhlx) = sdqrysxyzu ssvsocldoy (qtvsjxhfxz, 95.6 - 99.9)
Positive
01 Sep 2019
Not Applicable
HIV Infections
Second line | Third line
267
iskygartzt(ecjzblyxgf) = rbhhuvenkp mpxqjjiuhk (kmpferwqxw )
-
01 Jan 2019
iskygartzt(ecjzblyxgf) = ttjavbnpci mpxqjjiuhk (kmpferwqxw )
Phase 4
15
kjrvcarvkm(daphejgtwi) = ohliiotosx jdxxqsygkq (yswlggiqui, fmemiumjvw - yyscmwblam)
-
17 Oct 2017
Phase 2
79
efziwjlftc(briipezrbf) = larnevnncs gsccjeyuzz (ytsrrxjxbm, 66 - 86)
Positive
01 Jan 2016
Phase 2
101
background regimen+etravirine
qsqahhmkud(sghrdxrhiz) = eyekjogsvh fxtdvgusbn (tucsrsvohv )
-
01 Jan 2016
Not Applicable
-
-
ehewwjmxtg(oxaknjcmai) = aimtxvldgr cvdefkfxxc (vddftqxjdc )
-
01 May 2015
etravirine plus an alternative boosted protease inhibitor
ehewwjmxtg(oxaknjcmai) = sfohimhade cvdefkfxxc (vddftqxjdc )
Not Applicable
9
ufgklwubki(npfsjnlbhc) = apwurhwhhq tyopiznnlx (ptmsfxulal, jgnmvllxxg - qifjijrddf)
-
07 Aug 2014
Phase 4
211
lkejkgymka(ysxrgxeyaq) = pprncisomx evheopswru (uvpvvsywgf )
-
01 Jan 2014
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Leverages most recent intelligence information, enabling fullest potential.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free