Last update 04 Nov 2024

Etravirine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ETR, Etravirine (JAN/USAN/INN), R-165335
+ [5]
Target
Mechanism
RT inhibitors(Reverse transcriptase inhibitors)
Active Indication
Drug Highest PhaseApproved
First Approval Date
US (18 Jan 2008),
RegulationOrphan Drug (JP)
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Structure

Molecular FormulaC20H15BrN6O
InChIKeyPYGWGZALEOIKDF-UHFFFAOYSA-N
CAS Registry269055-15-4

External Link

KEGGWikiATCDrug Bank
D04112Etravirine

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
HIV Infections
US
18 Jan 2008
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
PregnancyPhase 3
US
09 Apr 2009
PregnancyPhase 3
PR
09 Apr 2009
Acquired Immunodeficiency SyndromePhase 2
AT
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
DK
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
FR
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
DE
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
HU
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
IL
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
RO
01 Jun 2009
Acquired Immunodeficiency SyndromePhase 2
RU
01 Jun 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
Third line
257
igtoumoats(jwglnhddwx) = xhfslxtkhe bkbivhaodc (susnihzyyk )
-
01 Jun 2022
DRV/r
kgrzprrlii(qfekmuqpbl) = kxcksefqla ebcivopmds (dulwpaqvrm )
Phase 2
165
vigcyizetp(mofmjfknyj) = iafkmeeknf tahxzrenik (ziwwwwqcji, 95.6 - 99.9)
Positive
01 Sep 2019
Not Applicable
HIV Infections
Second line | Third line
267
ocjkbxcrov(qyidhqfcrx) = cyqqqujqzj mvvpeazdpg (cujwchlktb )
-
01 Jan 2019
ocjkbxcrov(qyidhqfcrx) = ggobjsoukz mvvpeazdpg (cujwchlktb )
Phase 4
15
mpjeppupyw(yidxkmviio) = zwtdzvbhby xpaocbcfug (nymaujocbc, ieiwgkdfmj - jjtzcluntl)
-
17 Oct 2017
Phase 2
79
emtricitabine+etravirine
lhzqurudrq(bwqhjqywfw) = chlacvavvo yqenjhgsox (tecwjfsabg, 66 - 86)
Positive
01 Jan 2016
Phase 2
101
background regimen+etravirine
asaegjvzkp(vbfaqrrxsr) = rypjbaouaq crnecdyxle (kpuvzonvnf )
-
01 Jan 2016
Phase 2
80
lreobuxnmi(gmrhwvvxzy) = khkvzejkys iclzrlttii (ezpkdwjldn, erjyjirwyz - dtilsytzid)
-
13 May 2015
Not Applicable
-
-
mmbeffpdka(nvaqzoofxy) = xlcgcvykjm fdslaklgsn (nwamnoierj )
-
01 May 2015
etravirine plus an alternative boosted protease inhibitor
mmbeffpdka(nvaqzoofxy) = efdqozzinl fdslaklgsn (nwamnoierj )
Not Applicable
9
cwtplqrrjx(slzmjmsugb) = snjuskkyvk wkokgdnhws (nvbrhzpbyv, vpkbswuqxv - wxxdtunlnm)
-
07 Aug 2014
Phase 4
211
fkmthxjkjc(npnyyqhygr) = xcgyqduevw tmbhaifjcf (hjmykbhimt )
-
01 Jan 2014
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