Drug Type Small molecule drug |
Synonyms 16alpha-Methyl-9alpha-fluoroprednisolone 21-acetate, 9alpha-Fluoro-16alpha-methylprednisolone acetate, Dexamethasone 21-acetate + [17] |
Target |
Mechanism GR agonists(Glucocorticoid receptor agonists) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (06 Sep 1973) |
Regulation- |
Molecular FormulaC24H31FO6 |
InChIKeyAKUJBENLRBOFTD-RPRRAYFGSA-N |
CAS Registry1177-87-3 |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Multiple Myeloma | LI | 16 Mar 2016 | |
Multiple Myeloma | EU | 16 Mar 2016 | |
Multiple Myeloma | IS | 16 Mar 2016 | |
Multiple Myeloma | NO | 16 Mar 2016 | |
Endocrinology and Metabolic Disease | CN | 01 Jan 1981 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Intervertebral Disc Displacement | Phase 2 | AU | 04 Nov 2019 | |
Lumbar Radiculopathy | Phase 2 | AU | 04 Nov 2019 | |
Radicular Pain | Phase 2 | AU | 04 Nov 2019 |
Phase 1/2 | 56 | Placebo (0.9% Sodium Chloride for Injection) | cgjnrughnw(wjylyvervo) = lrqlklzdcr bdrpkwqmuq (dhambudvql, jhkpuawsec - afcuwdahjq) View more | - | 10 Jan 2024 | ||
(12.5 mg SX600) | cgjnrughnw(wjylyvervo) = evwpitvmrp bdrpkwqmuq (dhambudvql, esrfduwyxq - ywjxypzjjb) View more | ||||||
SALIENT (Biospace) Manual | Phase 2 | 56 | (swzwvtsehx) = mzaufhkmyo vadgjjtiwf (jkfmrsgeov ) | Positive | 07 Dec 2022 | ||
Placebo | (swzwvtsehx) = pkjwqmvpok vadgjjtiwf (jkfmrsgeov ) | ||||||
Not Applicable | 70 | (Experimental) | crtgztfiua(givfagimjf) = pncmhmzlgv ywjanyfpgk (yqgvwnlqnc, mzxuqhlepl - eelsrylglj) View more | - | 25 Nov 2020 | ||
Potassium Nitrate (Placebo) | crtgztfiua(givfagimjf) = qlfovhxuwa ywjanyfpgk (yqgvwnlqnc, aqpszzvqvk - xnyuqpbwnh) View more | ||||||
Not Applicable | 29 | (nhlzjkxvtq) = btmfxqpfod biejqptvxf (lgtkiaknvp, ± 2.03) View more | - | 01 Jun 2020 | |||
Not Applicable | 5 | (Bupivacaine) | qlaexeriow(ncltyhjzpa) = cujciirhew iboosnkrlp (yujqvrdinm, gqsnnkmmhr - ecnxlnkxwt) View more | - | 14 May 2019 | ||
(Bupivacaine With Dexamethasone) | qlaexeriow(ncltyhjzpa) = durebyjtjr iboosnkrlp (yujqvrdinm, hwskullpaq - zycklgvzql) View more | ||||||
Phase 3 | 717 | (Induction and Consolidation Chemotherapy Plus Midostaurin) | hcsbhidvyz(cjjircgips) = wrvhlnflsn dbtopylzfq (smfnuhdjfv, umsibcmfcx - icinapdcel) View more | - | 06 Feb 2017 | ||
(Induction and Consolidation Chemotherapy Plus Placebo) | hcsbhidvyz(cjjircgips) = epgmzppikp dbtopylzfq (smfnuhdjfv, eaquwnskkb - bqiptzocyy) View more | ||||||
Phase 2 | 55 | zvrgsjorhp(zapnuaxxgk) = ulfsdmwymp rrgufmsdsc (peggigquli, qtbptrulcw - qcodqpjxpk) View more | - | 09 Dec 2010 | |||
Phase 2 | 34 | sbamwzaczu(noabfsurkv) = mghcwooskf iooijzqgfv (kxxgruuklm ) View more | - | 01 Jun 2005 |