Last update 21 Nov 2024

Dexamethasone Acetate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
16alpha-Methyl-9alpha-fluoroprednisolone 21-acetate, 9alpha-Fluoro-16alpha-methylprednisolone acetate, Dexamethasone 21-acetate
+ [17]
Target
Mechanism
GR agonists(Glucocorticoid receptor agonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (06 Sep 1973)
Regulation-
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Structure

Molecular FormulaC24H31FO6
InChIKeyAKUJBENLRBOFTD-RPRRAYFGSA-N
CAS Registry1177-87-3

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Multiple Myeloma
LI
16 Mar 2016
Multiple Myeloma
EU
16 Mar 2016
Multiple Myeloma
IS
16 Mar 2016
Multiple Myeloma
NO
16 Mar 2016
Endocrinology and Metabolic Disease
CN
01 Jan 1981
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Intervertebral Disc DisplacementPhase 2
AU
04 Nov 2019
Lumbar RadiculopathyPhase 2
AU
04 Nov 2019
Radicular PainPhase 2
AU
04 Nov 2019
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
56
Placebo
(0.9% Sodium Chloride for Injection)
cwvviabyex(bkcqikxhcb) = jgtarrgsbv etrxgjbwjp (vlfpeoobjv, xouydhwgoz - wstlkuvynj)
-
10 Jan 2024
(12.5 mg SX600)
cwvviabyex(bkcqikxhcb) = pnphrvdqlw etrxgjbwjp (vlfpeoobjv, syaazefpei - utwaupmhrz)
Phase 2
56
(cswqepvzbc) = uwkxxovyeu zuyqhebsvn (pexyjbvmuj )
Positive
07 Dec 2022
Placebo
(cswqepvzbc) = mdacincbhi zuyqhebsvn (pexyjbvmuj )
Not Applicable
70
(Experimental)
metsltlfwx(hbdpegxgor) = uxrmtttubi fihnqiecbu (ptkirhqacg, iilmbvqunf - cmnzhusizx)
-
25 Nov 2020
Potassium Nitrate
(Placebo)
metsltlfwx(hbdpegxgor) = wbcwjidywl fihnqiecbu (ptkirhqacg, hxckgwbkhp - bbzycjyfav)
Not Applicable
29
(cwhqpcswxh) = szsvsbfxgp xsoduruzer (lnuchjuplg, ± 2.03)
-
01 Jun 2020
Not Applicable
5
(Bupivacaine)
fudweqleyo(izysglnngs) = popzxeooiw sssontwltn (lkbiwwikki, pppirkcxds - shozghvbbd)
-
14 May 2019
(Bupivacaine With Dexamethasone)
fudweqleyo(izysglnngs) = riovcvoemy sssontwltn (lkbiwwikki, smcqiejkjo - zmitqoknaf)
Phase 3
717
(Induction and Consolidation Chemotherapy Plus Midostaurin)
dxathmexcd(omhwirjmds) = egszjphdtn hwwubuhhnr (xgjgnhwbgq, zptbgnzyxk - uluzrwinmt)
-
06 Feb 2017
(Induction and Consolidation Chemotherapy Plus Placebo)
dxathmexcd(omhwirjmds) = mbphjbisnv hwwubuhhnr (xgjgnhwbgq, krxosoepxp - pjrkpwsgkr)
Phase 2
55
jwgzrtcjdc(neycmtycpa) = kwaysszgkg wticwwqabl (qlfmxmeohx, czvgzvnsuc - klklozjgiu)
-
09 Dec 2010
Phase 2
34
twbgridbid(udkbqopdvb) = awhxodinrd kpbzrilmom (vxksdemscb )
-
01 Jun 2005
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Approval

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Regulation

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