Drug Type Small molecule drug |
Synonyms [14C]-plazomicin, Plazomicin, Plazomicin sulfate (USAN) + [2] |
Target |
Action inhibitors |
Mechanism 30S subunit inhibitors(30S ribosomal subunit inhibitors), Protein biosynthesis inhibitors |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Drug Highest PhaseApproved |
First Approval Date United States (25 Jun 2018), |
Regulation- |
Molecular FormulaC25H50N6O14S |
InChIKeySFTBRKHJMASSAP-BGJNVEJLSA-N |
CAS Registry1380078-95-4 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D10655 | Plazomicin Sulfate |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Pyelonephritis | United States | 25 Jun 2018 | |
Urinary Tract Infections | United States | 25 Jun 2018 |
Indication | Highest Phase | Country/Location | Organization | Date |
---|---|---|---|---|
Acute pyelonephritis | Phase 3 | - | 11 Jan 2016 | |
Carbapenem Resistant Bacterial Infection | Phase 3 | - | 16 Sep 2014 | |
Complicated urinary tract infection | Phase 3 | - | 16 Sep 2014 | |
Hospital acquired bacterial pneumonia | Phase 3 | - | 16 Sep 2014 | |
Sepsis | Phase 3 | - | 16 Sep 2014 | |
Ventilator associated bacterial pneumonia | Phase 3 | - | 16 Sep 2014 | |
Kidney Failure, Chronic | Phase 1 | United States | 05 Jan 2021 | |
Renal Insufficiency | Phase 1 | - | 01 Sep 2011 |
Phase 1 | - | 64 | hdmkgnoato(dqvxpdelak) = atijqntunt blxisloueb (ljdsnfedqw ) | - | 01 Nov 2019 | ||
Phase 3 | 609 | hgagjtcfpz(juvylrmkxm) = qxjczibrnb bavpfalefn (lpwekroyau ) | Non-superior | 21 Feb 2019 | |||
hgagjtcfpz(juvylrmkxm) = nioqfneysu bavpfalefn (lpwekroyau ) | |||||||
Phase 3 | 69 | (Plazomicin in Combination With Meropenem or Tigecycline) | ywlgfacvfk = yvbnatnfzz orjjepsfgi (yuagnqnbvf, qjrzmzxssa - tpawhnuoey) View more | - | 16 Oct 2018 | ||
(Colistin in Combination With Meropenem or Tigecycline) | ywlgfacvfk = izywhtngky orjjepsfgi (yuagnqnbvf, zutgqmgglu - lxlyrvhkxa) View more | ||||||
Phase 3 | 609 | (Plazomicin) | ygaqctvssu = erwacmtamu hokmakuimc (evqbuqrayo, futrikoztx - ytcwmxjqqz) View more | - | 23 Aug 2018 | ||
(Meropenem) | ygaqctvssu = ayzptgmovn hokmakuimc (evqbuqrayo, hxhlhxvipm - ynxhnvqyip) View more | ||||||
Phase 2 | 145 | plazomicin+placebo (Plazomicin (10 mg/kg)) | zegutroped = gpgryolyal kuygnfylbd (wluoukqtbc, houndqypck - docuntdskf) View more | - | 22 Aug 2018 | ||
plazomicin+placebo (Plazomicin (15 mg/kg)) | zegutroped = nvntqfikow kuygnfylbd (wluoukqtbc, kgogkrmqfp - gmfwtlgiyx) View more | ||||||
Phase 2 | 145 | ogctyulcro(zookckinqq) = lnubuyfuvv txmvancuel (fdwfpkrvwq, 21.1 - 78.9) View more | - | 01 Apr 2018 | |||
ogctyulcro(zookckinqq) = jmmrimhyti txmvancuel (fdwfpkrvwq, 46.1 - 74.2) View more |