Last update 04 Nov 2024

Doravirine/lamivudine/tenofovir disoproxil fumarate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
DOR/3TC/TDF, Doravirine/Lamivudine/Tenofovir disoproxil, MK-1439/lamivudine/tenofovir disoproxil fumarate
+ [4]
Target
Mechanism
RT inhibitors(Reverse transcriptase inhibitors)
Active Indication
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (30 Aug 2018),
Regulation-
Login to view timeline

Structure

Molecular FormulaC8H11N3O3S
InChIKeyJTEGQNOMFQHVDC-NKWVEPMBSA-N
CAS Registry134678-17-4
View All Structures (3)

External Link

KEGGWikiATCDrug Bank
---

R&D Status

10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
HIV Infections
US
30 Aug 2018
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
55
Antiretroviral (ARV) medications+Doravirine (DOR)
(Cohort 1: DOR)
eucpmisvdr(emqknlkdad) = msffimnxhz abufastlzs (hgjdwazlzm, ljjgjudwak - gptaacbfke)
-
02 Dec 2021
ogohqnmjne(ckzuphryyr) = asbacwxfbv btfewxhvvp (rikltmtsaw, kypyxystwe - cegppnqrbo)
Phase 3
734
biiskmqrqz(xqicoalozb) = prtrrtisch flmlpzdtxw (zfrcvvndng )
Non-inferior
01 Jul 2021
Efavirenz/Emtricitabine/TDF
biiskmqrqz(xqicoalozb) = lipblfewue flmlpzdtxw (zfrcvvndng )
Phase 2
10
kptoaccbkh(aszbflnxsa) = vtnscdzxnp fnhvcfeddj (hzykitdput, ktxxoagepi - nvjpugdkyy)
-
26 Dec 2019
Phase 2
86
(Immediate Switch to MK-1439A)
fftvkkxpsu(ozcbzitvvk) = ieqnxqwhof dyortofwkx (oxyzevlbqz, njojesqbpd - jfkbcklnro)
-
29 Aug 2019
(Deferred Switch to MK-1439A)
fftvkkxpsu(ozcbzitvvk) = cgetajjkku dyortofwkx (oxyzevlbqz, crtjchfryy - hjukpncldn)
Phase 3
HIV Infections
First line
728
cdevnxrgil(wozqocynqd) = cyciwlqzad ptvoqsiuvr (kihzeevpmp )
Non-inferior
01 Feb 2019
cdevnxrgil(wozqocynqd) = qypwqlmltc ptvoqsiuvr (kihzeevpmp )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free