Last update 01 Nov 2024

Enistimagene Setitucel/Damistimagene Matitucel

Overview

Basic Info

Drug Type
Therapeutic vaccine, Immune cell therapy
Synonyms
GVAX Pancreas(Aduro Biotech), Panc 10.05/Panc 6.03(Aduro Biotech)
Target-
Mechanism
Immunostimulants
Therapeutic Areas
NeoplasmsDigestive System DisordersEndocrinology and Metabolic Disease
Active Indication
Secondary malignant neoplasm of pancreasPancreatic adenocarcinoma metastatic
Inactive Indication
AdenocarcinomaLocally Advanced Pancreatic Adenocarcinoma
Originator Organization
Aduro BioTech, Inc.Aduro BioTech, Inc.
Active Organization
The Sidney Kimmel Comprehensive Cancer CenterAduro BioTech, Inc.Aduro BioTech, Inc.
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
Login to view timeline

Related

9
Clinical Trials associated with Enistimagene Setitucel/Damistimagene Matitucel
NCT03153410 / CompletedEarly Phase 1IIT
A Pilot Study of a GVAX Pancreas Vaccine (With Cyclophosphamide) in Combination With a PD-1 Blockade Antibody (Pembrolizumab) and a Macrophage Targeting Agent (CSF1R Inhibitor) for the Treatment of Patients With Borderline Resectable Adenocarcinoma of the Pancreas
NCT03161379 / CompletedPhase 2IIT
A Phase II Clinical Trial of GVAX Pancreas Vaccine (With Cyclophosphamide) in Combination With Nivolumab and Stereotactic Body Radiation Therapy (SBRT) Followed by Definitive Resection for Patients With Borderline Resectable Pancreatic Adenocarcinoma
NCT03006302 / CompletedPhase 2IIT
Phase 2 Study of Epacadostat, Pembrolizumab, and CRS-207, With or Without Cyclophosphamide and GVAX Pancreas Vaccine in Patients With Metastatic Pancreas Cancer
100 Clinical Results associated with Enistimagene Setitucel/Damistimagene Matitucel
Login to view more data
100 Translational Medicine associated with Enistimagene Setitucel/Damistimagene Matitucel
Login to view more data
100 Patents (Medical) associated with Enistimagene Setitucel/Damistimagene Matitucel
Login to view more data
100 Deals associated with Enistimagene Setitucel/Damistimagene Matitucel
Login to view more data

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Locally Advanced Pancreatic AdenocarcinomaPhase 2
US
The Sidney Kimmel Comprehensive Cancer Center
18 Jul 2016
AdenocarcinomaPhase 2
US
Aduro BioTech, Inc.Aduro BioTech, Inc.
02 Jan 2015
Pancreatic adenocarcinoma metastaticPhase 2
US
Aduro BioTech, Inc.Aduro BioTech, Inc.
21 Sep 2011
Secondary malignant neoplasm of pancreasPhase 2
US
Aduro BioTech, Inc.Aduro BioTech, Inc.
21 Sep 2011
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT03153410 (CTgov)
Early Phase 1
Pancreatic adenocarcinoma
12
IMC-CS4+cyclophosphamide+GVAX Pancreas Vaccine (GVAX)+pembrolizumab+GVAX
fidxccatqu(uqohskywsx) = dcoonpzsqu uxistybbit (tzxierwqkd, ydrifstsye - frxjxlsxic)
View more
-
15 Oct 2024
NCT02648282 (CT134, CTgov)
Phase 2
Locally Advanced Pancreatic Adenocarcinoma
58
motozlaxzu(qbwpichjgr) = ikgaidoaxr moglokmnin (umajaletrg, jzeqxkxjux - ufavpgpwbl)
View more
-
28 Feb 2023
NCT01417000 (Phase IIa, CTgov)
Phase 2
Pancreatic adenocarcinoma metastatic | Secondary malignant neoplasm of pancreas
93
(Cy/GVAX + CRS-207)
sifizugbpc(rdmfilqxvh) = djzstdukhs wzarnopjso (xwniniegyz, nnjuqnaeyd - lizxpaxxqs)
View more
-
08 May 2018
(Cy/GVAX)
sifizugbpc(rdmfilqxvh) = woketbugqr wzarnopjso (xwniniegyz, thwkbmrgvp - confdenooz)
View more
NCT02004262 (ECLIPSE, CTgov)
Phase 2
Pancreatic adenocarcinoma metastatic | Secondary malignant neoplasm of pancreas
303
(Primary Cohort: Cy/GVAX + CRS-207)
dmyltuxcsm(uiadzwnvkb) = trokrlmrre ypdmtgljqs (huhsodeekg, wtrdyrfghb - ngnxggjywb)
View more
-
03 May 2018
(Primary Cohort: CRS-207)
dmyltuxcsm(uiadzwnvkb) = phkzhcypkv ypdmtgljqs (huhsodeekg, awfzkdlhmm - lrwxlcqlar)
View more
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
login
or
view full example data
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
login
or
view full example data
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
login
or
view full example data
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
login
or
view full example data
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
login
or
view full example data
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
login
or
view full example data
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free