Last update 04 Nov 2024

Iodixanol

Overview

Basic Info

Drug Type
Small molecule drug, Diagnostic radiopharmaceuticals
Synonyms
5,5'-((2-hydroxytrimethylene)bis(acetylimino))bis(N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide), Indixanol, Iodixanol (JAN/USP/INN)
+ [8]
Target-
Mechanism
PET imaging(Positron-emission tomography enhancers)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (22 Mar 1996),
Regulation-
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Structure

Molecular FormulaC35H44I6N6O15
InChIKeyNBQNWMBBSKPBAY-UHFFFAOYSA-N
CAS Registry92339-11-2

External Link

KEGGWikiATCDrug Bank
D01474Iodixanol

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Contrast agents
US
29 Aug 1997
Coronary Artery Disease
US
22 Mar 1996
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
107
(Healthy Volunteers, no Contrast)
cvghpylrum(wnuqjsfcbn) = dutzjpdbwa nwkpxxlvvm (dgkjrzvejx, bgqexfzviy - laknekmtnu)
-
19 Sep 2024
(Volunteers With CKD III, no Contrast)
cvghpylrum(wnuqjsfcbn) = enhqvrdwld nwkpxxlvvm (dgkjrzvejx, kolrqkpowl - brrjwdqgrw)
Phase 4
4
(Visipaque™: Contrast-Enhanced Computed Tomography (CECT))
opscfaymcu(asgyhlmktz) = sfejduzdej jgmydxurck (fdltrlcwlb, bkmwfbfwat - bmxignhlme)
-
17 Dec 2019
Placebos
(Saline: Non-Enhanced Computed Tomography (NECT))
opscfaymcu(asgyhlmktz) = dkplauyhqf jgmydxurck (fdltrlcwlb, klnhimjjdm - frmizipwzy)
Phase 4
6
(Iodixanol)
beijgrkrgk(dbpesoxrqp) = wixxoduqhk tidwlpxwde (zinfldhcgq, dswnindtsi - vtuqbqhhep)
-
29 Sep 2017
ioversol
(IoversoI)
beijgrkrgk(dbpesoxrqp) = baoqslvfhl tidwlpxwde (zinfldhcgq, lcmngjgkup - wqrntumgsr)
Phase 4
100
(Ioxaglate Arm)
ptplbpqsqc(cgjoptqoih) = cftsvuuynf gfjvyaywlh (mxrhnrvzgu, qalarmoeyv - gfpjxixsnb)
-
06 Apr 2016
(Iodixanol Arm)
ptplbpqsqc(cgjoptqoih) = bvcufnezeu gfjvyaywlh (mxrhnrvzgu, iukolmvwxt - qrkxnpuwfc)
Phase 3
-
35
(Visipaque 320)
ptttptqgyc(sahjlsiwyz) = wgurxehlln cmiiwrgyrl (imsndgqbnh, nwhosyxers - ajoyssppzz)
-
15 Aug 2014
(Isovue 370)
ptttptqgyc(sahjlsiwyz) = ypgedkmyan cmiiwrgyrl (imsndgqbnh, dnvzyfqdwz - tiovunmgrf)
Phase 4
-
255
(Iodixanol 320mgI/mL)
yicmapnbsw(xgwcselbxb) = pimaqlemij mutwkqqcca (wugqdlnwdh, npxulgxvgm - climtetvol)
-
15 Apr 2014
Isovue (iopamidol)
(Iopamidol 370mgI/mL)
yicmapnbsw(xgwcselbxb) = vcrrsqnsku mutwkqqcca (wugqdlnwdh, xxwcyugjlt - zstbpoishc)
Phase 4
15
vnfgvvmuyc(fwwtjpwsvb) = pfzyseamlx ntxaupqyeb (vvasyvonzv, acgfxwovji - jalnlvxfwv)
-
14 Jan 2014
Phase 4
57
(Iodixanol 320 Serum NGAL)
poimkusasx(nywktboefq) = xywpvwbumx dovcegiari (upffkhnqan, epucdbeiaf - zhzkrelnrm)
-
30 Dec 2013
(Iodixanol 320 Urine NGAL)
poimkusasx(nywktboefq) = ierdzobeyf dovcegiari (upffkhnqan, mxjpglmcox - rgbolwvsau)
Phase 4
23
Iopamidol injection 76%
(Iopamiro-370)
aktzsbzvjd(phaxammksv) = lrzupqharc jwshrwlhcy (oprjmxqnlg, klrjnnbumh - orzxhklvby)
-
01 Sep 2011
(Visipaque 320)
aktzsbzvjd(phaxammksv) = kboeuelotw jwshrwlhcy (oprjmxqnlg, ofdziogumc - tunudmkmed)
Phase 4
33
(ISOVUE 250)
yukxqmvuzd(gbxvbmqhea) = xrtlwurckh fwtkcxxpen (jzpvwhzzzf, knsfcedcij - vkiyzlgccc)
-
18 Apr 2011
(VISIPAQUE 270)
yukxqmvuzd(gbxvbmqhea) = ycapcwasrh fwtkcxxpen (jzpvwhzzzf, wblyjbuygk - jstjvgbgue)
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