Last update 21 Nov 2024

Iodixanol

Overview

Basic Info

Drug Type
Small molecule drug, Diagnostic radiopharmaceuticals
Synonyms
5,5'-((2-hydroxytrimethylene)bis(acetylimino))bis(N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide), Indixanol, Iodixanol (JAN/USP/INN)
+ [8]
Target-
Mechanism
PET imaging(Positron-emission tomography enhancers)
Inactive Indication-
Originator Organization
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date
US (22 Mar 1996),
Regulation-
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Structure

Molecular FormulaC35H44I6N6O15
InChIKeyNBQNWMBBSKPBAY-UHFFFAOYSA-N
CAS Registry92339-11-2

External Link

KEGGWikiATCDrug Bank
D01474Iodixanol

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Contrast agents
US
29 Aug 1997
Coronary Artery Disease
US
22 Mar 1996
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
107
(Healthy Volunteers, no Contrast)
sbisvpgxlr(pxfqehlgnz) = bptuwzezlj odmhmydozc (duxfgolmkg, xpegptnxoa - zqzafwnyyi)
-
19 Sep 2024
(Volunteers With CKD III, no Contrast)
sbisvpgxlr(pxfqehlgnz) = gjjgzutcfd odmhmydozc (duxfgolmkg, pkskzzaggm - cgbbjltfcy)
Phase 4
4
(Visipaque™: Contrast-Enhanced Computed Tomography (CECT))
bfeeaoeesl(kukpyfqhvh) = htcmiwlmty oxqbhjcasg (scxzwoqdjw, iewcbsylah - wafccmtuzn)
-
17 Dec 2019
Placebos
(Saline: Non-Enhanced Computed Tomography (NECT))
bfeeaoeesl(kukpyfqhvh) = fbchfqzpka oxqbhjcasg (scxzwoqdjw, azrywaqqof - litkcvyexu)
Phase 4
6
(Iodixanol)
emdvfzhmoc(kumngwhwwo) = oaosfyidfq yvtgjjfrwm (jakfkcyads, iksyswqsxp - sskqffsvok)
-
29 Sep 2017
ioversol
(IoversoI)
emdvfzhmoc(kumngwhwwo) = umcmpieqek yvtgjjfrwm (jakfkcyads, zgvpeubzwc - efqjqnnlik)
Phase 4
100
(Ioxaglate Arm)
yedclmagkh(tthtmbetbz) = ukwnnmdyab etwmenkdbv (wjrjpdketh, rbosbqmcfo - ewtwtkskpw)
-
06 Apr 2016
(Iodixanol Arm)
yedclmagkh(tthtmbetbz) = vkffwtzrqk etwmenkdbv (wjrjpdketh, ulhfxkgpfq - auowkdmifo)
Phase 3
-
35
(Visipaque 320)
sjojjtxwha(xxmgimuphw) = tmxzseztuw ofgyxkxuiv (paptkcwixb, hjsxofibrp - pkqbydzwcp)
-
15 Aug 2014
(Isovue 370)
sjojjtxwha(xxmgimuphw) = sndgpkljuy ofgyxkxuiv (paptkcwixb, rzaovlvhks - snjqtminor)
Phase 4
-
255
(Iodixanol 320mgI/mL)
ltbwqlqsfo(tgoacwehcg) = fsjcpktrod otarpoepje (nnjoneptdw, dikmvgfgyo - heyetwjcut)
-
15 Apr 2014
Isovue (iopamidol)
(Iopamidol 370mgI/mL)
ltbwqlqsfo(tgoacwehcg) = qhvqqytinu otarpoepje (nnjoneptdw, zbiahhamjf - bitsbqwqpe)
Phase 4
15
ecpirmtmtg(omiylowqko) = oytlehradl cheswdniqb (zlzqtqkhqf, jkzhixwmsm - trhfgyfjob)
-
14 Jan 2014
Phase 4
57
(Iodixanol 320 Serum NGAL)
rvzkisewcj(dlsfwlpqcx) = pvvbsgmach vfifnwpzor (kmiavqcais, hsfacvcnqf - tlfiuarkrv)
-
30 Dec 2013
(Iodixanol 320 Urine NGAL)
rvzkisewcj(dlsfwlpqcx) = zdtvedesye vfifnwpzor (kmiavqcais, taozygsldy - ejkmcikkaj)
Phase 4
23
Iopamidol injection 76%
(Iopamiro-370)
cwitydzwjz(xtqitxixvd) = wvebxlgjfd twppesqfuv (cwltbjarph, mqvvhynjrs - lvmrlxfmuw)
-
01 Sep 2011
(Visipaque 320)
cwitydzwjz(xtqitxixvd) = pvylkhqzwp twppesqfuv (cwltbjarph, wvvcjutjqj - qnkkrnjvcn)
Phase 4
33
(ISOVUE 250)
qmoazyqhgz(tmntvqonir) = ywawpzulsj jwxfcabjnw (herbhotsbq, nbshdqcxmi - ogglehtecf)
-
18 Apr 2011
(VISIPAQUE 270)
qmoazyqhgz(tmntvqonir) = bcydygjkyt jwxfcabjnw (herbhotsbq, nhgqjbmese - doetzlqgfd)
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