The U.S. FDA has approved the use of Pfizer's BRAFTOVI® combination therapy as a first-line treatment for metastatic colorectal cancer with BRAF V600E mutations.
Marengo has dosed its initial patient in the Phase 2 clinical trial of Invikafusp Alfa (STAR0602) targeting PD-1 resistant tumors and is extending the study to Europe.
Oruka Therapeutics reports that the initial participants have received doses in the Phase 1 trial of ORKA-001, a new antibody that extends half-life and targets IL-23p19.
TRYNGOLZA™ (olezarsen) has received U.S. approval as the first treatment for adults with familial chylomicronemia syndrome, used alongside dietary changes.