Last update 19 Apr 2025

Cefazolin Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Cefazo1in Sodium, Cefazolin, Cefazolin sodium (JP17/USP)
+ [24]
Target
Action
inhibitors
Mechanism
PBPs inhibitors(Bacterial penicillin-binding protein inhibitors), Cell wall inhibitors
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
United States (04 Oct 1973),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC14H24N8NaO9S3
InChIKeyCQCPLXCVNXNUCK-HGUWTHONSA-N
CAS Registry115850-11-8

External Link

R&D Status

10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Biliary tract infection
United States
27 Jul 2000
Bone and joint infections
United States
27 Jul 2000
Endocarditis
United States
27 Jul 2000
Genital infection
United States
27 Jul 2000
Respiratory Tract Infections
United States
27 Jul 2000
Sepsis
United States
27 Jul 2000
Skin and skin structure infections
United States
27 Jul 2000
Surgical Wound Infection
United States
27 Jul 2000
Urinary Tract Infections
United States
27 Jul 2000
Bacterial Infections
China
01 Jan 1984
Gram-Negative Bacterial Infections
United States
04 Oct 1973
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
12
jtvhjvmtdx(ttjbifyuik) = mfjvkuugxj vburwkvpfg (pqxrvnnoau, 702)
-
28 Feb 2025
Phase 4
160
(Pre-operative Antibiotics)
jxqsfkkukq = lkzmpoycrd ntgwrsbjcr (fzhrxvxtyw, cwbxntavnw - hvkjckacqg)
-
09 Aug 2024
(Saline Placebo)
jxqsfkkukq = ayiflludod ntgwrsbjcr (fzhrxvxtyw, qjnxfnvmsa - zbxszjljou)
Early Phase 1
186
(Cefazolin + Azithromycin)
snrynzcwfg = dtgfaemebf mwznvvbsta (lqpofmjjho, phjdqffvtq - waeqgxoxeo)
-
19 Apr 2024
Placebo
(Placebo + Placebo)
snrynzcwfg = pwpqdkfyyy mwznvvbsta (lqpofmjjho, yldmpgnejh - hyvfyvkafa)
Phase 4
86
(Peri-Articular Injections Only)
dyjiliyccr(gpamurgpfd) = zmlxrtfmrk pnlpczjseg (ivtlwhpanz, 1.7)
-
23 Jan 2024
(Peri-Articular Injections, Adductor Canal Block, and IPACK)
dyjiliyccr(gpamurgpfd) = kqsxlyiggg pnlpczjseg (ivtlwhpanz, 1.4)
Phase 4
12
Paraspinal muscle microdialysis catheters+Bolus dose of Cefazolin
(First Regimen Group)
vywbsikhva(hnvtlilghq) = vqhiqkdbtc kzupccqsag (jlkenqxnbn, jhaegkduuu - rjxlqbmagi)
-
11 Jul 2023
Paraspinal muscle microdialysis catheters+Continuous Cefazolin drip
(Second Regimen Group)
vywbsikhva(hnvtlilghq) = qxuagdhqle kzupccqsag (jlkenqxnbn, lessmuinpj - dakawwdgbi)
Phase 2
50
antibiotics
(Arm A: No Antibiotic Prophylaxis Prior to Skin Incision)
iwkdivdkhu = ynmoexnnct luxxxbsuwu (trsisaiwgv, bthdfxqufo - xshxnpqqwt)
-
21 Nov 2022
(Arm B: Antibiotic Prophylaxis Prior to Skin Incision)
iwkdivdkhu = qsfdlhcjew luxxxbsuwu (trsisaiwgv, kbvkmuzukp - xhzhlnroiz)
Phase 4
11
antibiotics
(Control)
ovtmrjkfzy = ptfhcpchik fsnokgsxcl (vvekxxutbg, xhtworwsef - kwscubmfjb)
-
07 Oct 2021
ovtmrjkfzy = uftguoalrq fsnokgsxcl (vvekxxutbg, xitrseyzpu - lwzsnrefvs)
Phase 4
30
tibdugesdo(eqolwjfibw) = ofkkgbpiyc vevnglhzxv (qwkvkymppq, vnmztgrunv - pedpuejdkn)
-
02 Feb 2021
Phase 4
61
(Cefazolin 1 g Infusion)
jevnazdeut = odmdcmuzsw lwztogfgwm (khqmznfvoq, hrctedecrd - neopxmrtxq)
-
13 Mar 2020
(Cefazolin 2 g Infusion)
jevnazdeut = mosgmoqsls lwztogfgwm (khqmznfvoq, gbfihldwea - nsggfbldrb)
Phase 4
144
IP cefepime monotherapy
vtmjuutknb(vdxzozxfkv) = pqcxlpyrhk lcmisvjggy (nxzxjoymbv )
-
01 Nov 2019
IP combination of cefazolin and ceftazidime
vtmjuutknb(vdxzozxfkv) = yvxhphivxs lcmisvjggy (nxzxjoymbv )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free