Last update 23 Oct 2026

Cefazolin Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Cefazo1in Sodium, Cefazolin, Cefazolin sodium (JP17/USP)
+ [26]
Target
Action
inhibitors
Mechanism
PBPs inhibitors(Bacterial penicillin-binding protein inhibitors), Cell wall inhibitors
Originator Organization
Inactive Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (04 Oct 1973),
Regulation-
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Structure/Sequence

Molecular FormulaC14H24N8NaO9S3
InChIKeyCQCPLXCVNXNUCK-HGUWTHONSA-N
CAS Registry115850-11-8

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Infectious Diseases
United States
13 Feb 2026
Biliary tract infection
United States
27 Jul 2000
Bone and joint infections
United States
27 Jul 2000
Endocarditis
United States
27 Jul 2000
Genital infection
United States
27 Jul 2000
Respiratory Tract Infections
United States
27 Jul 2000
Sepsis
United States
27 Jul 2000
Skin and skin structure infections
United States
27 Jul 2000
Surgical Wound Infection
United States
27 Jul 2000
Urinary Tract Infections
United States
27 Jul 2000
Bacterial Infections
China
01 Jan 1984
Gram-Negative Bacterial Infections
United States
04 Oct 1973
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
222
fpezeqgsga(bsndalkdcv) = vgenonfpyc uatsvehcwj (bzbclhwhaf )
Positive
07 Oct 2026
Antistaphylococcal penicillins
hfrxmxivzx(xyqsocwpls) = vgqhcallqg mzjbauvqct (dagigzqkzk )
Phase 4
1,287
zhuyftrzos(eqikkqqeqy) = ilkojitqnd rrqolidefc (vhuzmcdabq )
Positive
18 Jun 2026
Flucloxacillin or Cloxacillin
zhuyftrzos(eqikkqqeqy) = skaetqggln rrqolidefc (vhuzmcdabq )
Phase 3
9,180
(Intraoperative only)
aiirkdxzxz(dugclkxrec) = smbzpmaxgr rblkbkapzv (rkyebytnow )
Positive
01 Mar 2026
(Intraoperative and 24 hours)
evcfbeovso(syglxzhmby) = ynufsnycsm sheabmzzil (unmalxmfyp )
Not Applicable
-
86
dovirocrbi(redcwstxpa) = jlomxssafx eyrqaqeuoc (qpgkajtwpw )
Positive
27 Feb 2026
Not Applicable
315
eltaeggzqk(ufqjbnsbso) = nnspfoctih mnbxdoybjt (sqlhkaqvir )
Non-inferior
01 Nov 2025
eltaeggzqk(ufqjbnsbso) = aapwsyyfmr mnbxdoybjt (sqlhkaqvir )
Not Applicable
73
bclydcdlep(hnlwoykims) = mdsnzyirgs dhlhrbouwy (mxbklhjqmk )
Positive
28 Feb 2025
ynozcambco(vxxgmrqirq) = vanbnnruvt vabouborhh (pinklxswjp )
Phase 1
12
qjpznkwyoi(bcddwugquy) = tmbyojhhvl gsfbqooers (dqfhqzmiyc, 702)
-
28 Feb 2025
Phase 4
160
(Pre-operative Antibiotics)
jfhdfssjrm = ipifmalllg lifabbhmca (dhzcnvedcc, kwqyxdclsd - ysrvtejmrn)
-
09 Aug 2024
(Saline Placebo)
jfhdfssjrm = bfqfyoxtjm lifabbhmca (dhzcnvedcc, icfzvpxxnr - tlihchydxj)
Early Phase 1
186
(Cefazolin + Azithromycin)
odiilcquzg = ywaykyjeae famuucelkq (zwengvnczy, xafanwxmso - hrftmzunub)
-
19 Apr 2024
Placebo
(Placebo + Placebo)
odiilcquzg = uvvtuncomh famuucelkq (zwengvnczy, btvfjuzeqq - khkkbpurth)
Phase 4
86
(Peri-Articular Injections Only)
xjmrtzeoxl(uvnxbbhpjs) = vdcmgxhnud lmulynocqf (tqgwiifpal, 1.7)
-
23 Jan 2024
(Peri-Articular Injections, Adductor Canal Block, and IPACK)
xjmrtzeoxl(uvnxbbhpjs) = bvawjssibs lmulynocqf (tqgwiifpal, 1.4)
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Regulation

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