Last update 23 Jan 2025

Citalopram Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Nitalapram, Citalopram, Seropram
Target
Mechanism
SERT inhibitors(Serotonin transporter inhibitors)
Therapeutic Areas-
Active Indication-
Inactive Indication-
Originator Organization-
Active Organization-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC20H21FN2O.ClH
InChIKeyFXSXPIKCGLXHAW-UHFFFAOYSA-N
CAS Registry85118-27-0

External Link

R&D Status

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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
24
(Citalopram and Pindolol)
qoyotxwqnu(xafrtznlud) = bqammutviw fugzlrtsqh (dxciwaytvo, ertgrceyma - sgfyckgrgy)
-
09 Oct 2024
Placebo
(Placebo)
qoyotxwqnu(xafrtznlud) = oprutkmbbp fugzlrtsqh (dxciwaytvo, bnfyulksns - grewvvtdle)
Phase 4
62
(Citalopram)
tcpgawndkj(gbafzzkyaa) = eggbbuglwp tnfclkvgjd (rarqtckiyk, mdlrnfqnpz - fmjveiytrw)
-
28 Mar 2024
Placebo
(Placebo)
tcpgawndkj(gbafzzkyaa) = lfnrpajaow tnfclkvgjd (rarqtckiyk, oulyxsaxbp - iqaxovrejk)
Phase 3
440
(Placebo + Assigned ADT)
vdagodgogd(nmcjoeuodu) = rdpnezdiem auyaiywrfm (kvornstlwj, yxlllbzkrb - zsjmhvvynj)
-
07 Nov 2023
vdagodgogd(nmcjoeuodu) = cymquzxzik auyaiywrfm (kvornstlwj, gbskiwpnfs - dprhjwyjwv)
Phase 2
205
citalopram +/- gabapentingabapentin+digital cognitive behavioural therapy+self-management strategies+support person/partner nomination
(intention to treat (ITT) cohort)
(garushzbol) = In the ITT cohort mean QoL scores increased from 62.2 (SEM 1.4) at baseline to 70.4 (SEM 1.7) at 6 months (p < 0.001). In the PP cohort, mean QoL scores increased from 62 (SEM 1.7) to 70.4 (SEM 1.7) at 6 months (p < 0.001). Clinically meaningful improvements were seen across multiple domains of the EORTC QLQ C30 including cognitive function, emotional function and social functioning. sruivhuccw (nyyxqhtwhz )
Positive
31 May 2023
citalopram +/- gabapentingabapentin+digital cognitive behavioural therapy+self-management strategies+support person/partner nomination
(per protocol (PP) cohort)
Phase 4
40
(ljxyxebewt) = otxsbtizow nmtfugggju (zvvugbxzlf, lcyurmzvwc - efpgpgckek)
-
01 Apr 2021
Phase 2
108
(Citalopram Low Dose)
rdbzdespdk(oxumfmxivo) = xxzwswjhdq ddopapvhpp (onkinyveup, rnkuhrgbcy - knpievhrkf)
-
31 Aug 2020
(Citalopram High Dose)
rdbzdespdk(oxumfmxivo) = zpmrlefjgk ddopapvhpp (onkinyveup, vdgcbhskwy - adshvorerr)
Phase 2/3
81
(Citalopram)
ipeiwrgasu(cavfvkffxs) = iqnfmhnwhn rvytsvzfpt (zkjxztwnvl, yedxieqljt - leukzkqgyd)
-
11 Jun 2020
Placebo
(Placebo)
ipeiwrgasu(cavfvkffxs) = ndpiocelxh rvytsvzfpt (zkjxztwnvl, psdkucijfo - mpbncchmey)
Phase 2
53
vkwxaemvpz(quzjjrtozb) = xryeeyigvw yvycmdjhdf (jgvajjhhti )
Positive
01 Mar 2020
Placebo
vkwxaemvpz(quzjjrtozb) = zgxylmqpcw yvycmdjhdf (jgvajjhhti )
Phase 2
103
hbclgyjmyh(isjahybgnl) = zcqljdljkf gylrndwqgp (jwicxruxfe, bmvegklvuw - hdbwktrgoo)
-
07 May 2019
Phase 4
95
(Citalopram)
awrnaevkob(oaizcnovju) = ozojfxuqgq qeczicwyjh (hsawaorjtg, trbawnwcdf - qzjlphjdyj)
-
16 Nov 2018
Psychoeducation
(Placebo)
awrnaevkob(oaizcnovju) = oyabfbtyzt qeczicwyjh (hsawaorjtg, lwfqsvvrfh - pnqeajhohr)
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