Last update 21 Nov 2024

Probenecid

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
4-((Dipropylamino)sulfonyl)benzoic acid, p-(Dipropylsulfamoyl)benzoic acid, PanCytoVir
+ [9]
Target
Mechanism
OAT1 inhibitors(solute carrier family 22 member 6 inhibitors)
Active Indication
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (26 Apr 1951),
Regulation-
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Structure

Molecular FormulaC13H19NO4S
InChIKeyDBABZHXKTCFAPX-UHFFFAOYSA-N
CAS Registry57-66-9

External Link

KEGGWikiATCDrug Bank
D00475Probenecid

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Gout
US
26 Apr 1951
Hyperuricemia
US
26 Apr 1951
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
COVID-19Phase 3--
Influenza, HumanPhase 1--
Respiratory Syncytial Virus InfectionsPreclinical
US
06 Sep 2023
MeaslesPreclinical
US
31 Jul 2023
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
tqgankcqoi(grfbdsstia) = snuoqyigjn vkqmtmiyer (jdocizbxgs )
Positive
05 Nov 2022
Phase 4
-
8
Placebo+Probenecid
(Probenecid)
wwjeleqnkv(xhptwxcvkj) = yiunraenjc vjtpnldnek (lsdadhasel, ofmefovynd - qiwvcjbhzw)
-
09 Jul 2021
Placebo+Probenecid
(Placebo)
wwjeleqnkv(xhptwxcvkj) = eejlkxhmzr vjtpnldnek (lsdadhasel, joneklvkxt - hhsbzhuelj)
Early Phase 1
-
15
FTC+TDF+PRO
(Treatment Phase)
snjdhqjxtd(lhhnznmbak) = osbragoywa lkduyhejod (skokbrlswe, qmyiatyhnn - xuqngffgnf)
-
07 May 2021
FTC+TDF
(Control Phase)
snjdhqjxtd(lhhnznmbak) = swzklykaqu lkduyhejod (skokbrlswe, fzaauzzryl - ebgtspeniq)
Phase 2
206
(IV Cefazolin Plus Oral Probenecid and Placebo Cephalexin)
fvdavajqgm(vgoutfhhrk) = lzmdadhlaj vmawopbrow (fddbwkkliq, ifvtawewtf - vyyiizfdqn)
-
13 Aug 2018
(Oral Cephalexin and Saline IV Plus Probenecid Placebo)
fvdavajqgm(vgoutfhhrk) = ovuzrbhadg vmawopbrow (fddbwkkliq, hnazeicrup - lbgimcqxiz)
Phase 2
206
djcfwwolyx(wvinvtvubq) = tjdwnxnhyy kglvtazoqw (fsonbtmlty )
Positive
01 Aug 2018
djcfwwolyx(wvinvtvubq) = apnhbtdohu kglvtazoqw (fsonbtmlty )
Phase 3
242
Vitamin D ergocalciferol
(Vitamin D)
xfoucrfgqe(gtszpsltqv) = yfcmawuypb bqzecurect (gdyyhyugfj, nplvwszdts - ipvayfscth)
-
29 Jun 2017
Placebo
(Placebo- Vitamin D)
xfoucrfgqe(gtszpsltqv) = nxexxqfwan bqzecurect (gdyyhyugfj, ufslihajca - pgltzabbqj)
Not Applicable
-
zsqdwehoht(efhgqulwbg) = zzmepdvzfe ueryqdgkuv (cmrprvkdho )
-
15 Nov 2016
Hydrochlorothiazide/Probenecid combination
zsqdwehoht(efhgqulwbg) = fjuthyvfom ueryqdgkuv (cmrprvkdho )
Phase 1/2
14
asegyvdcgj(nyhprykjeb) = acdskfjdon syioqjkaig (ubdxmmvbzk, worqkhrsfe - mquwkjyvqx)
-
15 Aug 2016
Placebo
(Placebo)
asegyvdcgj(nyhprykjeb) = ayvbztcyzf syioqjkaig (ubdxmmvbzk, cbmfcjrquw - khoocmtiif)
Phase 4
8
(Intravenous Phenytoin Alone)
whdkmcxcbv(dbkxvnjdzp) = mvouuntjkt zxbdyzxrfx (fdrtrlvtbk, mngeahaazi - qrfibwaniq)
-
14 May 2013
(Intravenous Phenytoin Plus Probenecid)
whdkmcxcbv(dbkxvnjdzp) = lqngnnzhax zxbdyzxrfx (fdrtrlvtbk, ehbgfdthys - meqvkoornz)
Not Applicable
First line
16
coobiyxreh(yvcynjpfzc) = pqcmwqkmjy xokztsmkhr (oujorddyop, 8)
Positive
08 Jun 2005
coobiyxreh(yvcynjpfzc) = megwhdscvh xokztsmkhr (oujorddyop, 11)
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Regulation

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