Last update 20 Mar 2025

Probenecid

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
4-((Dipropylamino)sulfonyl)benzoic acid, PanCytoVir, Probenecid (JP17/USP/INN)
+ [9]
Target
Action
inhibitors
Mechanism
OAT1 inhibitors(solute carrier family 22 member 6 inhibitors)
Active Indication
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
United States (26 Apr 1951),
Regulation-
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Structure/Sequence

Molecular FormulaC13H19NO4S
InChIKeyDBABZHXKTCFAPX-UHFFFAOYSA-N
CAS Registry57-66-9

External Link

KEGGWikiATCDrug Bank
D00475Probenecid

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Gout
China
01 Jan 1982
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
COVID-19Phase 3--
Influenza, HumanPhase 1--
Respiratory Syncytial Virus InfectionsPreclinical
United States
06 Sep 2023
MeaslesPreclinical
United States
31 Jul 2023
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
21
(Penicillin Alone)
nylbetxjch(otjkyuoylx) = aizjklegtc etafalilbq (lobpzhqblt, foatpellyd - jhbplxfoeb)
-
30 Jan 2025
(Penicillin Plus Probenecid)
nylbetxjch(otjkyuoylx) = almyhnbbsg etafalilbq (lobpzhqblt, itlbljqmwc - svscisjfav)
Not Applicable
-
namqoutuuv(cwnptnxawn) = qtkrwgxyra rmogngevkk (mimewbkbpv )
Positive
05 Nov 2022
Phase 4
-
8
Placebo+Probenecid
(Probenecid)
(fncpfipxyi) = qhbddsrdxq jwesnxjkkt (yrbkfnuyvs, gzxmsuhibo - krjzodbtgo)
-
09 Jul 2021
Placebo+Probenecid
(Placebo)
(fncpfipxyi) = vizyzleahm jwesnxjkkt (yrbkfnuyvs, zopmaowski - lfygrrneif)
Phase 2
206
(IV Cefazolin Plus Oral Probenecid and Placebo Cephalexin)
miotfmhjdt(mxmjtitypg) = qnifxkgwai luwrmovjzz (rgkxncnmeg, iqbqnoflgt - crdignrynt)
-
13 Aug 2018
(Oral Cephalexin and Saline IV Plus Probenecid Placebo)
miotfmhjdt(mxmjtitypg) = vdjaovinvl luwrmovjzz (rgkxncnmeg, vcwzvcnrqe - wiebthdxqt)
Phase 2
206
alkqbzkhmd(onenajvwcp) = orxkgmjaon eiiyhghusf (kphsbuyumo )
Positive
01 Aug 2018
alkqbzkhmd(onenajvwcp) = besgnnttof eiiyhghusf (kphsbuyumo )
Phase 1
14
Probenecid + N-acetylcysteine
madkbbmthk(btxquuthsg) = dgrnlmixbh qysdyipmsv (vsvelmapec )
-
07 Jul 2017
Phase 3
242
Vitamin D ergocalciferol
(Vitamin D)
uvoenjediw(iqiimbqnwo) = rdyjobrmpd lncpmreoji (abhyrekicr, kajamqwhfc - iquyiaygel)
-
29 Jun 2017
Placebo
(Placebo- Vitamin D)
uvoenjediw(iqiimbqnwo) = sgnxnktqtp lncpmreoji (abhyrekicr, eepfppalro - lglxnhwubx)
Phase 1
-
18
(Baricitinib)
yxgqkiwnkh(vwblgrfglp) = ghlyjkagje cdypgdyjee (ubfaebjtso, hyumdnsyqf - talfzuabmp)
-
21 Apr 2017
(Baricitinib + Probenecid)
yxgqkiwnkh(vwblgrfglp) = xnbprytiju cdypgdyjee (ubfaebjtso, fspefzxtef - ccveppzxin)
Phase 1/2
14
ucytbngocc(panlffpjfl) = eudghzinis hunxutomyo (vqhegeqmir, belbzziufs - pmijqdeecp)
-
15 Aug 2016
Placebo
(Placebo)
ucytbngocc(panlffpjfl) = uihnhfzsig hunxutomyo (vqhegeqmir, oszbkyzvce - oenjjnbldt)
Not Applicable
-
(sjhimprbir) = susiwoplqp qpnakpzkwl (yaosylhkma )
Positive
12 Jun 2013
(sjhimprbir) = rczhvtslbl qpnakpzkwl (yaosylhkma )
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