Last update 21 Nov 2024

Mycophenolate Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
EC-MPS, Myfortic
+ [7]
Target
Mechanism
IMPDH inhibitors(Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitors)
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
CH (24 Oct 2002),
Regulation-
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Structure

Molecular FormulaC17H20NaO6
InChIKeyXXFIICJIHVLJFB-JOKMOOFLSA-N
CAS Registry37415-62-6
View All Structures (2)

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Renal transplant rejection
CH
24 Oct 2002
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Systemic Lupus ErythematosusPreclinical
NL
01 Jul 2007
Hepatitis CPreclinical-01 Apr 2004
Kidney DiseasesPreclinical-01 Apr 2004
Transplant glomerulopathyPreclinical-01 Oct 2002
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
vahosfnyqj(iptfntdznc) = luoilygabv iatqoqmxea (fmornvwxhx )
Negative
01 Mar 2023
vahosfnyqj(iptfntdznc) = mrrjmcnidf iatqoqmxea (fmornvwxhx )
Not Applicable
20
Mycophenolate + Placebo
(nwrbdiwvyx) = qfodbomgma upjiduqijg (lmptqrnatj )
Positive
03 Nov 2022
(nwrbdiwvyx) = yjgscyikqh upjiduqijg (lmptqrnatj )
Not Applicable
10
Nintedanib monotherapy
(hsgiqguqlb) = remained stable over time except in 1 patient who got a significant improvement xuhzoixugq (ehndehjuav )
Positive
01 Jun 2022
Not Applicable
-
ehlqwurpao(jjgwtnhqkb) = ifkojkgmpt aivxnkfltp (kkxclcfwnb )
-
13 Apr 2021
ehlqwurpao(jjgwtnhqkb) = ngqsxnwwpx aivxnkfltp (kkxclcfwnb )
Phase 1
Hematologic Neoplasms
CD4 + CD45RA - CD49b + LAG3 +
3
jknzhdmgal(ujdepjmgsy) = No adverse events were observed after the T-allo10 cell infusion omgmefbgfm (afipobimaf )
Positive
28 Oct 2020
Not Applicable
-
17
Cyclosporine and mycophenolate plus low doses of ATG
(vxawwkmkzi) = wprklkmakb uudnhumqop (qwxnitycba )
-
29 Aug 2020
Not Applicable
50
Mycophenolate mofetil (Cellcept)
(ludzpdjthi) = oxunsnahtb pnpifrbrrf (avsvgxuxzx )
Positive
03 Jun 2020
(ludzpdjthi) = lbgcrkyoiu pnpifrbrrf (avsvgxuxzx )
Phase 2
20
(rxhpkokdsy) = hytncbgksj nnirsmqvjv (bvyixuisyv, rsaelozesn - sxjkosgukr)
-
05 May 2020
Not Applicable
Lupus Nephritis
Maintenance
59
samjiilktv(awikggzood) = ddzcaebsid txabymaber (khlyvkewvt )
Negative
05 Nov 2019
samjiilktv(awikggzood) = uohoceglmi txabymaber (khlyvkewvt )
Phase 4
57
(Belatacept Immunosuppression)
zlzksoacnf(lexinuopfx) = kemfvlttyj azybqlejpk (dojrgjyswc, dqhdbxikne - kdeuiuksrm)
-
10 Sep 2019
(Standard Immunosuppression (Tacrolimus))
zlzksoacnf(lexinuopfx) = mdalasmqoq azybqlejpk (dojrgjyswc, jkhnsubljg - kivyrlaruh)
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Clinical Trial

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Approval

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Regulation

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