Last update 16 May 2024

Envafolimab

Overview

Basic Info

Drug Type
Single-domain antibody
Synonyms
+ [2]
Target
Mechanism
PDL1 inhibitors(Programmed death-ligand 1 inhibitors)
Inactive Organization
Drug Highest PhaseApproved
RegulationConditional marketing approval (CN), Fast Track (US), Orphan Drug (US), Priority Review (CN), Breakthrough Therapy (CN)
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External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Microsatellite Instability-high Solid Tumors
MO
15 Jan 2024
Advanced Malignant Solid Neoplasm
CN
24 Nov 2021
Microsatellite instability-high cancer
CN
24 Nov 2021
Mismatch repair-deficient Solid Tumors
CN
24 Nov 2021
Mismatch repair-deficient Solid Tumors
CN
24 Nov 2021
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Non-Small Cell Lung CancerPhase 3
CN
17 Nov 2023
Locally Advanced Rectal CarcinomaPhase 3
CN
01 Apr 2023
Biliary Tract NeoplasmsPhase 3
CN
16 Apr 2018
Biliary Tract NeoplasmsPhase 3
CN
16 Apr 2018
Advanced CholangiocarcinomaPhase 3--
Microsatellite Instability-high Solid TumorsPhase 2
CN
22 Aug 2018
Microsatellite instability-high colorectal cancerPhase 2
CN
03 Aug 2018
Microsatellite instability-high colorectal cancerPhase 2
CN
03 Aug 2018
Esophageal CarcinomaDiscovery
CN
24 Jul 2018
Esophageal CarcinomaDiscovery
CN
24 Jul 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
73
(cohort C)
(dykfjawtxh) = nafkkzyixo ilcteluhtl (zzquivhljx )
Positive
03 Apr 2024
Phase 2
49
kuaytgklwc(nctcaypoog) = the acceptable safety profile nphtropcra (rrafddqefq )
Positive
12 Nov 2023
placebo
Phase 2
29
Envafolimab+Rh-endostatin+platinum-based dual-agent chemotherapy
(iqubqlooyq) = qubmjobwdg auqdsbjlax (cxxuwgnfxl, 54.3 - 85.3)
Positive
20 Mar 2024
Phase 1/2
24
-
Positive
23 Oct 2023
(PD-(L)1 resistant NSCLC)
(ymkaegnkeg) = wfbosgqdrg zxhcxjtxhs (hhudydkvaw, 6.0 - 61.0)
Phase 2
40
(gtyukgotfk) = qzrnechciz fqfntsoyjz (oclendtmoh )
Positive
24 Jan 2023
Phase 2
21
(afejrnyceo) = pfsmmthlrn hweukhdzqu (fswzgiinvp )
Positive
24 Jan 2023
Phase 2
PD-L1 positive stomach adenocarcinoma
First line
PD-L1 Expression
9
(wybiuxziyd) = lqavluapul rdrplelrds (jdsayuguhe )
Positive
31 May 2023
Phase 2
36
Envafolimab + Gemcitabine + Cisplatin
(btzxyzplhj) = irraddzhio kygltbmpes (clxcsnetjv, 85.5 - 99.9)
Positive
22 Oct 2023
Phase 2
Microsatellite Stable Colorectal Carcinoma | Colorectal Cancer
Second line
TP53 mutation | KRAS | PI3KCA ...
20
(grnxmiludn) = gbocgnqdbe qsnpifigiy (basfjcqyyb, 8.7 - 49.1)
Positive
22 Oct 2023
Phase 2
46
(xmsgmrxewa) = jjhnckfdvv cwejtwzpdb (nxaiihjcau )
Positive
20 Dec 2023
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Regulation

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