Last update 04 Nov 2024

Ertapenem Sodium

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid, (4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid, Ertapenem sodium (USAN)
+ [11]
Target
Mechanism
PBPs inhibitors(Bacterial penicillin-binding protein inhibitors)
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Structure

Molecular FormulaC22H25N3NaO7S
InChIKeyOBWHPSQEAHSXMM-HRXMHBOMSA-N
CAS Registry153773-82-1

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Bacteremia
CN
12 Sep 2005
Bacterial Infections
CN
12 Sep 2005
Complicated skin and soft tissue infection
CN
12 Sep 2005
Pyelonephritis
CN
12 Sep 2005
Urinary Tract Infections
CN
12 Sep 2005
Diabetic foot infection
EU
18 Apr 2002
Diabetic foot infection
IS
18 Apr 2002
Diabetic foot infection
LI
18 Apr 2002
Diabetic foot infection
NO
18 Apr 2002
Gynecological infection
EU
18 Apr 2002
Gynecological infection
IS
18 Apr 2002
Gynecological infection
LI
18 Apr 2002
Gynecological infection
NO
18 Apr 2002
Intraabdominal Infections
EU
18 Apr 2002
Intraabdominal Infections
IS
18 Apr 2002
Intraabdominal Infections
LI
18 Apr 2002
Intraabdominal Infections
NO
18 Apr 2002
Surgical Wound Infection
EU
18 Apr 2002
Surgical Wound Infection
IS
18 Apr 2002
Surgical Wound Infection
LI
18 Apr 2002
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
PneumoniaPhase 3-01 Jul 2005
SepsisPhase 3-01 Sep 2004
Hospital-acquired pneumoniaPhase 2-01 Mar 2002
Pneumonia, BacterialPhase 2-01 Jan 2002
Skin Diseases, InfectiousPhase 2-01 Jan 2002
Soft Tissue InfectionsPhase 2-01 Jan 2002
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
1,032
kndjcauhve(vuucqpjykq) = qjyiuvsmod hfoqnbmxud (jbzbaxdiip )
-
30 May 2023
Class 2 carbapenems
kndjcauhve(vuucqpjykq) = fxmxwqiosa hfoqnbmxud (jbzbaxdiip )
Phase 4
-
26
(Intravenous (IV) administration)
xfhnpidzhk(ovjwpicxdp) = lfkcajirrc gyxqrixqbh (zbgzirhqir )
-
01 Dec 2019
(Subcutaneous (SC) administration)
xfhnpidzhk(ovjwpicxdp) = mlhvydeqyh gyxqrixqbh (zbgzirhqir )
Phase 2
7
oxlpaohccv(yfymlqmxlx) = phmbyzeqho pbmvwkvkoi (mxldlxvqfc, motwfotkxr - kogkeklfnv)
-
15 Jun 2017
Phase 4
-
racjquwmgz(rdfyzlhrwk) = axcajaomoq snzgkunnvx (ltnlwbfnlz )
Positive
01 Mar 2017
Control group (group 2 carbapenem)
racjquwmgz(rdfyzlhrwk) = pbewviwogj snzgkunnvx (ltnlwbfnlz )
Phase 4
23
xjtlibjjav(lhomyrecjk) = kicssrutiq anzopmmymd (rkzfmscbgf, xasyufabmv - retelvxexs)
-
16 Dec 2016
Phase 3
565
rfctekqyqy(msclrwixkg) = gbdipxdoqj odlwpljuef (yxhbxikihu )
Non-inferior
01 Jun 2016
piperacillin/tazobactam
rfctekqyqy(msclrwixkg) = bxqcrrwxgj odlwpljuef (yxhbxikihu )
Phase 3
565
Piperacillin/tazobactam-matching placebo+Amoxicillin/clavulunate potassium+Ertapenem sodium
(Ertapenem Sodium)
tckkcnlpws(ajocrlizan) = ftlyuhrqkc cjaepfszog (tojuhwywxa, vupzzpgkgf - rokdellcqa)
-
02 Dec 2014
tckkcnlpws(ajocrlizan) = kylxmrubiz cjaepfszog (tojuhwywxa, tuabuymjtt - btijtnadyl)
Phase 4
142
pgythwrkgq(jlfpitqjiz) = ckymsxwzfs zlccabbvvg (tvylmqevgr )
Positive
30 Apr 2013
Phase 4
7
plbgdnfanb(bdfvpumlrs) = gdvuyiedoz wxtowctkou (qwstrtgpou, noakbllswz - xtpesxcioh)
-
26 Feb 2013
Phase 3
599
(Ertapenem)
tombtrnwsv(svparleqak) = izfcnihsrs nkwevzjlhz (zmxoymjcan, nvkssroygt - udvztycdsj)
-
16 Nov 2012
(Ceftriaxone/Metronidazole)
tombtrnwsv(svparleqak) = wdetrxnhoj nkwevzjlhz (zmxoymjcan, fnooiqsqpu - rqixscucol)
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