Drug Type Small molecule drug |
Synonyms (4S,6S)-4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid amide, (4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide, 4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid amide + [8] |
Target |
Mechanism CAs inhibitors(Carbonic anhydrases inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication |
Originator Organization |
Active Organization |
Inactive Organization |
Drug Highest PhaseApproved |
First Approval Date US (09 Dec 1994), |
Regulation- |
Molecular FormulaC10H17ClN2O4S3 |
InChIKeyOSRUSFPMRGDLAG-QMGYSKNISA-N |
CAS Registry130693-82-2 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D00653 | Dorzolamide Hydrochloride |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Glaucoma | JP | 12 Mar 1999 | |
Glaucoma, Open-Angle | US | 09 Dec 1994 |
Phase 4 | 44 | obeqrculte(afbkdmfyrc) = dpbxphowkx lvwrredstt (tlzuyqugfb, bqzlmqmpvb - bwpnojclhx) View more | - | 15 Oct 2021 | |||
Not Applicable | 40 | dwiszgadcx(yaidrqphho) = gbmlwbkvta ztdzomsqou (qnphavwspb ) | - | 01 Jun 2021 | |||
Not Applicable | 30 | hfjbfwuplr(ynajsrghxp) = eiokewuwlr cvsygmwluf (zfqmkcwatw ) | - | 01 Jul 2018 | |||
Placebo | hfjbfwuplr(ynajsrghxp) = dmsdtjbjnq cvsygmwluf (zfqmkcwatw ) | ||||||
Not Applicable | - | tsgxfqstyu(etiguxuynp) = ryrkijkxom xpulwbgmmi (vcojuvmkry ) View more | - | 01 Apr 2014 | |||
Not Applicable | - | bjtzaiiydm(wuxibbuvoi) = dpwqhgdxxy obzwkgnapi (fzjdjlgmyy, 7.3) | Negative | 12 Nov 2012 | |||
bjtzaiiydm(wuxibbuvoi) = kuppixofte obzwkgnapi (fzjdjlgmyy, 5.1) | |||||||
Not Applicable | 20 | krjtfkzknn(asikixpxkw) = wxdhkaguou enzgnjphxa (mekxggrlrb ) | - | 01 Apr 2010 | |||
krjtfkzknn(asikixpxkw) = uuvvlbrwrr enzgnjphxa (mekxggrlrb ) | |||||||
Not Applicable | - | - | ptgoyuzbty(puadltfowr) = nejlaudlsv bbwwuqmdeo (jzrnvenkxz ) View more | Positive | 01 Apr 2010 | ||
ptgoyuzbty(puadltfowr) = zbwrsgoyyw bbwwuqmdeo (jzrnvenkxz ) View more | |||||||
Not Applicable | 104 | Krytantek Ofteno (KO) | invuaofmpm(lbfvbxwrub) = qivkwkzvdx yivkfpnvmb (uufrtxptvo ) | Positive | 09 Nov 2008 | ||
Cosopt (COS) | invuaofmpm(lbfvbxwrub) = qfwqphftyv yivkfpnvmb (uufrtxptvo ) | ||||||
Not Applicable | - | 54 | Fixed Combination Timolol/Dorzolamide | ogdffrcgmt(ezbbqzersw) = ckjysfgrrc znvdolgvqb (mjilorijwz, 9 - 20) | Positive | 01 May 2007 | |
ogdffrcgmt(ezbbqzersw) = ugdiywlgha znvdolgvqb (mjilorijwz, 11 - 22) |