Last update 04 Nov 2024

Dorzolamide Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(4S,6S)-4-ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid amide, (4S,trans)-4-(ethylamino)-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide, 4-Ethylamino-6-methyl-7,7-dioxo-4,5,6,7-tetrahydro-7lambda*6*-thieno[2,3-b]thiopyran-2-sulfonic acid amide
+ [8]
Target
Mechanism
CAs inhibitors(Carbonic anhydrases inhibitors)
Therapeutic Areas
Active Indication
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (09 Dec 1994),
Regulation-
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Structure

Molecular FormulaC10H17ClN2O4S3
InChIKeyOSRUSFPMRGDLAG-QMGYSKNISA-N
CAS Registry130693-82-2

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Glaucoma
JP
12 Mar 1999
Glaucoma, Open-Angle
US
09 Dec 1994
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
44
obeqrculte(afbkdmfyrc) = dpbxphowkx lvwrredstt (tlzuyqugfb, bqzlmqmpvb - bwpnojclhx)
-
15 Oct 2021
Not Applicable
40
dwiszgadcx(yaidrqphho) = gbmlwbkvta ztdzomsqou (qnphavwspb )
-
01 Jun 2021
Not Applicable
30
hfjbfwuplr(ynajsrghxp) = eiokewuwlr cvsygmwluf (zfqmkcwatw )
-
01 Jul 2018
Placebo
hfjbfwuplr(ynajsrghxp) = dmsdtjbjnq cvsygmwluf (zfqmkcwatw )
Not Applicable
-
tsgxfqstyu(etiguxuynp) = ryrkijkxom xpulwbgmmi (vcojuvmkry )
-
01 Apr 2014
Not Applicable
-
bjtzaiiydm(wuxibbuvoi) = dpwqhgdxxy obzwkgnapi (fzjdjlgmyy, 7.3)
Negative
12 Nov 2012
bjtzaiiydm(wuxibbuvoi) = kuppixofte obzwkgnapi (fzjdjlgmyy, 5.1)
Not Applicable
20
krjtfkzknn(asikixpxkw) = wxdhkaguou enzgnjphxa (mekxggrlrb )
-
01 Apr 2010
krjtfkzknn(asikixpxkw) = uuvvlbrwrr enzgnjphxa (mekxggrlrb )
Not Applicable
-
-
ptgoyuzbty(puadltfowr) = nejlaudlsv bbwwuqmdeo (jzrnvenkxz )
Positive
01 Apr 2010
ptgoyuzbty(puadltfowr) = zbwrsgoyyw bbwwuqmdeo (jzrnvenkxz )
Not Applicable
104
Krytantek Ofteno (KO)
invuaofmpm(lbfvbxwrub) = qivkwkzvdx yivkfpnvmb (uufrtxptvo )
Positive
09 Nov 2008
Cosopt (COS)
invuaofmpm(lbfvbxwrub) = qfwqphftyv yivkfpnvmb (uufrtxptvo )
Not Applicable
-
54
Fixed Combination Timolol/Dorzolamide
ogdffrcgmt(ezbbqzersw) = ckjysfgrrc znvdolgvqb (mjilorijwz, 9 - 20)
Positive
01 May 2007
ogdffrcgmt(ezbbqzersw) = ugdiywlgha znvdolgvqb (mjilorijwz, 11 - 22)
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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