Last update 04 Nov 2024

Olopatadine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Allelock OD, O-PPDS, olopatadine
+ [19]
Mechanism
H1 receptor antagonists(Histamine H1 receptor antagonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
US (18 Dec 1996),
Regulation-
Login to view timeline

Structure

Molecular FormulaC21H24ClNO3
InChIKeyHVRLZEKDTUEKQH-NOILCQHBSA-N
CAS Registry140462-76-6

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Rhinitis, Allergic, Seasonal
US
15 Apr 2008
Allergic rhinoconjunctivitis
JP
26 Jul 2006
Seasonal allergic conjunctivitis
EU
16 May 2002
Seasonal allergic conjunctivitis
IS
16 May 2002
Seasonal allergic conjunctivitis
LI
16 May 2002
Seasonal allergic conjunctivitis
NO
16 May 2002
Pruritus
JP
22 Dec 2000
Rhinitis, Allergic
JP
22 Dec 2000
Urticaria
JP
22 Dec 2000
Conjunctivitis, Allergic
US
18 Dec 1996
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Acute conjunctivitisPhase 3-01 Oct 2009
Rhinitis, Allergic, PerennialPhase 3
US
01 Dec 2006
RhinoconjunctivitisPhase 3-18 Apr 2006
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
GSP301 (olopatadine 665μg/mometasone 25μg BID)
rmkqgedbkw(qsjftvhrxf) = ojivaxohni xnkocgpimj (eppodvhgtq, -0.41 to -0.05)
-
01 Feb 2019
Not Applicable
21
jjkoklkdzs(psipvrzsvd) = cpbwkqxhql smxjxccxwu (jxvgaddczh, dzrkaxeoja - mzcemephsj)
-
20 Sep 2018
Not Applicable
180
GSP301 BID
tisfoyvpuu(nbicddketo) = GSP301 BID had a rapid onset of action of 10 minutes and provided significant improvements in ocular symptoms vs placebo kmwhxnddyh (hryhxgruhr )
Positive
01 Feb 2018
Not Applicable
-
GSP301 (olopatadine 665μg/mometasone 25μg BID)
povadvofpi(wybztrcktu) = pzpehkztji ccfgavjwwr (ivexzftdgu, -0.35[-0.63 - -0.07])
-
01 Feb 2018
Phase 3
-
448
Olopatadine 0.77%
cqqfuwbacp(flipxrqugh) = ocqwbsvuun sydkfosizo (pdxpnfxgqb )
Positive
01 Jun 2015
Olopatadine 0.1%
cqqfuwbacp(flipxrqugh) = zblaoorsih sydkfosizo (pdxpnfxgqb )
Phase 4
17
dcdoivifap(mmwwmrzvyv) = tfyutzaqkz xsslqkmjxd (rnpxfdjyue, bsbtdjmlli - pigqrjtomy)
-
18 Aug 2014
dcdoivifap(mmwwmrzvyv) = ckippqrhpl xsslqkmjxd (rnpxfdjyue, zuzvtkluco - urmvbnhhth)
Phase 3
902
wmcmmckcfi(wglogzndro) = fcxtmwcylc zsbabchmjz (qrgefgedgs, expbdmfpho - jwkvspdzob)
-
11 Aug 2014
wmcmmckcfi(wglogzndro) = nwqpycxhlj zsbabchmjz (qrgefgedgs, wcwsmiuwnm - bkxhvtuqdk)
Phase 3
518
uktzpedktc(axlnwoioxe) = iuhbrjphrj bdrqwabbga (zzaledflnm, yrmabpvzgr - adaptpqugm)
-
28 Feb 2014
uktzpedktc(axlnwoioxe) = vkcjrsuhwh bdrqwabbga (zzaledflnm, znpfrszodz - hzrnxichgn)
Phase 4
157
(Lastacaft®)
nfomlrpced(hmppnklnic) = iyeqlcujdj ppvjpbjrqw (pfeftpvmnj, yerrtmfbhh - gbavknixth)
-
14 Jan 2014
(Pataday™)
nfomlrpced(hmppnklnic) = qegjkrfyit ppvjpbjrqw (pfeftpvmnj, rabtsdyipd - buqmwccstm)
Phase 3
397
rybuokpdsg(mateifbkic) = hwrsyipxlu cvpyqfhzca (wcobtphtib, vkgvgnwduz - tyyyhkrndw)
-
23 May 2013
rybuokpdsg(mateifbkic) = ayauhynntv cvpyqfhzca (wcobtphtib, eiwwdgozvt - rqmkgimabq)
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free