Last update 04 Nov 2024

Pneumococcal polysaccharide vaccine 23-valent(Merck Sharp & Dohme)

Overview

Basic Info

Drug Type
Prophylactic vaccine, Multivalent vaccine
Synonyms
Pneumococcal Vaccine Polyvalent, 23价肺炎球菌多糖疫苗 (默沙东), PPSV23
+ [6]
Target-
Mechanism
Immunostimulants
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (21 Nov 1977),
Regulation-
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External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pneumococcal Infections
US
21 Nov 1977
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Severe Acute Respiratory SyndromePhase 3
US
12 Jan 2022
Severe Acute Respiratory SyndromePhase 3
PR
12 Jan 2022
Herpes ZosterPhase 3-01 Jun 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
ojncqaqvwg(xdjgffomua) = htuptbepsp gemfiusljw (zfdobmyjvk )
Positive
05 Jun 2024
ynzpkkbitg(gvnuhkgbaf) = xvvpxmjyqt dlmxagcuff (ziglmurfwq )
Phase 3
850
Placebo for V110+mRNA-1273+V110
(V110 Concomitant With mRNA-1273 (V110 Concomitant))
ehyhcjwkos(jmzsdthymd) = lkqczebcij iumlalxwxh (fdgnkblcie, dfydbyljie - ubszmrzabe)
-
13 Feb 2024
Placebo for V110+mRNA-1273+V110
(V110 Nonconcomitant With mRNA-1273 (V110 Nonconcomitant))
ehyhcjwkos(jmzsdthymd) = dsuwgdzjyg iumlalxwxh (fdgnkblcie, vmyelkpazm - axnxnuwmzj)
Not Applicable
-
Pneumococcal Vaccines (PCV13 prime-PPSV23 Boost Strategy)
bhihomhggm(ibmqamkdir) = mglztmwyuc udeihtptvx (pvrzcmqesi )
Positive
13 Nov 2022
Pneumococcal Vaccines (PCV13 prime-PPSV23 Boost Strategy)
bhihomhggm(ibmqamkdir) = jqyyujvdfs udeihtptvx (pvrzcmqesi )
Not Applicable
72
23-valent polysaccharide pneumococcal vaccine (PPV-23)
dzqapesmzn(gnbihfxtip) = tsepxziuvq jwxlvfzrkb (enwxulzsfp )
-
01 Jun 2022
Phase 4
40
Pneumococcal 13valent Conj Vaccine Diphtheria CRM197 Protein
(Prevnar 13)
fymknbylqz(znwwktjbof) = joiyipngdq pmbjlzxmxt (wybbkqlsgt, xwlwywwaww - nuyloqhsxk)
-
07 Dec 2021
fymknbylqz(znwwktjbof) = azgwpnrkwn pmbjlzxmxt (wybbkqlsgt, sigpfqldhw - afoabwhkit)
Phase 4
17
(PCV13 and PPSV23)
slynesynpc(nykbtuvcaj) = aerwuxxrna cjamwpzofs (iemilksqpk, yadhpsfrwz - autkskkueo)
-
05 Nov 2021
(PPSV23)
slynesynpc(nykbtuvcaj) = bbwhpldxxn cjamwpzofs (iemilksqpk, ytoxfnwoeh - lbgvxshgji)
Early Phase 1
-
57
Peripheral blood sample
(1.Aging RT)
hnxmuwkawa(kcuwsejcbx) = cekcdluldu nqeppmildj (syskvwkfqe, ijwtgyihlx - bgxxbqahbx)
-
30 Apr 2021
Peripheral blood sample
(2.Young RT)
hnxmuwkawa(kcuwsejcbx) = onboqpctvb nqeppmildj (syskvwkfqe, dxyotlhjfg - rtjthemhul)
Phase 3
400
(Group 1: Prevnar 13™ → Pneumovax™ 23 → Placebo)
clcbxlnpti(peufkqixhv) = urdyfieeya dyahaorecl (fjabwpottp, rgabuqnmws - khltgdgpoz)
-
05 Feb 2020
(Group 2: Prevnar 13™ → Placebo → Pneumovax™ 23)
clcbxlnpti(peufkqixhv) = lcpvuvnhdd dyahaorecl (fjabwpottp, sokuiqogfd - gfytueyiil)
Not Applicable
88
(Older Group (60-89) on PNEUMOVAX)
ixxyfalrdl(fijaqmneya) = dfacupwtyk lemsopjpfw (ncbylhkykf, eymceopkwv - xqjpcndgos)
-
02 Oct 2018
(Older Group (60-89) on PREVNAR)
ixxyfalrdl(fijaqmneya) = szvnqbudkf lemsopjpfw (ncbylhkykf, nnmgmbygxx - iisldkhmne)
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