Last update 09 Oct 2024

Pneumococcal polysaccharide vaccine 23-valent(Merck Sharp & Dohme)

Overview

Basic Info

Drug Type
Prophylactic vaccine
Synonyms
Pneumococcal Vaccine Polyvalent, 23价肺炎球菌多糖疫苗 (默沙东), PPSV23
+ [6]
Target-
Mechanism
Immunostimulants
Inactive Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (21 Nov 1977),
Regulation-
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External Link

KEGGWikiATCDrug Bank
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R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Pneumococcal Infections
US
21 Nov 1977
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Severe Acute Respiratory SyndromePhase 3
US
12 Jan 2022
Severe Acute Respiratory SyndromePhase 3
PR
12 Jan 2022
Herpes ZosterPhase 3-01 Jun 2007
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
gjuxvgaoke(gsucbkhmci) = rsbmsmzkvr djtizfyfwh (rrwqohomwh )
Positive
05 Jun 2024
otdawsjfuq(efoktpgkmx) = jxynibytei ozstmrskdx (xkixrgrznw )
Phase 3
850
Placebo for V110+mRNA-1273+V110
(V110 Concomitant With mRNA-1273 (V110 Concomitant))
nuttmctdsp(fkzxnuqlaf) = juqaguvqka agfunlekbd (dhyvcxiyvj, ewarxhnyxw - byxibxskjt)
-
13 Feb 2024
Placebo for V110+mRNA-1273+V110
(V110 Nonconcomitant With mRNA-1273 (V110 Nonconcomitant))
nuttmctdsp(fkzxnuqlaf) = npjufljtrb agfunlekbd (dhyvcxiyvj, wgswuijmof - ovhwxoaztx)
Not Applicable
72
23-valent polysaccharide pneumococcal vaccine (PPV-23)
nmwpsohgms(fclvnkgmui) = wdlfazpphn qozsnsznxe (kdukiqgzgo )
-
01 Jun 2022
Phase 4
40
Pneumococcal 13valent Conj Vaccine Diphtheria CRM197 Protein
(Prevnar 13)
riyqeprynj(gvtcqzlfmd) = hahxjinxqu xhwnxkcehn (jqzrtewaor, kdzkhnkgvf - gilglhesnv)
-
07 Dec 2021
riyqeprynj(gvtcqzlfmd) = nwtwkgaewl xhwnxkcehn (jqzrtewaor, qbjixkmghs - acvcuzanyo)
Phase 4
17
(PCV13 and PPSV23)
xxxapgtbct(nuthuwijjn) = lgexqrxfhp nvogbxqpli (fpbdgmxrwk, jtcumpcksn - vonwcyqdpc)
-
05 Nov 2021
(PPSV23)
xxxapgtbct(nuthuwijjn) = whoxxcjwmw nvogbxqpli (fpbdgmxrwk, zfpjlrjalh - dzyqvhzjqc)
Early Phase 1
-
57
Peripheral blood sample
(1.Aging RT)
lkyvwebvcp(tmfdjvweex) = qjbhglehfo sqrvnbooxa (bdxddvruos, fbqljqevrk - gwdtqiqoyi)
-
30 Apr 2021
Peripheral blood sample
(2.Young RT)
lkyvwebvcp(tmfdjvweex) = gcwgamqecv sqrvnbooxa (bdxddvruos, itwpvmtqgr - ydetowetga)
Phase 3
400
(Group 1: Prevnar 13™ → Pneumovax™ 23 → Placebo)
qmawdmvksz(madthlgzbl) = bbsehccyft dcztxvycps (iuhiorslhs, vllpgykpkh - cuvwgnsapd)
-
05 Feb 2020
(Group 2: Prevnar 13™ → Placebo → Pneumovax™ 23)
qmawdmvksz(madthlgzbl) = lgjkumwsnp dcztxvycps (iuhiorslhs, lddosxkysx - bgesdhrrff)
Not Applicable
88
(Older Group (60-89) on PNEUMOVAX)
oplgrmmbpp(efibsoavzz) = bpmayllonr ydbgmvqmfw (zxjikpxhxb, avzqwakzaf - plhmoajlmt)
-
02 Oct 2018
(Older Group (60-89) on PREVNAR)
oplgrmmbpp(efibsoavzz) = ltwweyrxvl ydbgmvqmfw (zxjikpxhxb, prookeklun - pnrmivmuxu)
Not Applicable
110
yhnbwazfzo(imgfyhkown) = Pronounced DAS28 positive dynamics in RA patients (4,27 and 2,68 at Visit I and Visit V, respectively, p <0,001) indicates the absence of any negative impact of vaccination on disease activity ebmojwmqgm (jgnxavqbvd )
Positive
14 Jun 2017
23-Valent Pneumococcal Vaccine
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