Last update 17 May 2025

Chloroprocaine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
2-chloroprocaine, 4-amino-2-chlorobenzoic acid 2-(diethylamino)ethyl ester, Ampres
+ [12]
Action
blockers
Mechanism
Sodium channels blockers
Inactive Indication
Originator Organization
Inactive Organization
License Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC13H20Cl2N2O2
InChIKeySZKQYDBPUCZLRX-UHFFFAOYSA-N
CAS Registry3858-89-7

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Anesthesia
United States
11 Mar 1955
Neurolytic Block
United States
11 Mar 1955
Tissue infiltration
United States
11 Mar 1955
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Eye DiseasesNDA/BLA
Canada
01 Feb 2025
CataractPhase 3
Italy
09 Sep 2020
CataractPhase 3
Slovakia
09 Sep 2020
CataractPhase 3
Spain
09 Sep 2020
AnalgesiaPhase 3
Belgium
01 Oct 2016
FlatfootPhase 2
Italy
14 Feb 2019
FlatfootPhase 2
Spain
14 Feb 2019
Hernia, InguinalPhase 2
Italy
14 Feb 2019
Hernia, InguinalPhase 2
Spain
14 Feb 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
110
(1% Chloroprocaine (PF))
unlfwlndsa(nxchchgqez) = ojbuximhit mcyvtljyxa (mtacwlqvrx, 8.6)
-
28 Feb 2025
(0.75% Bupivacaine)
unlfwlndsa(nxchchgqez) = damazpddcl mcyvtljyxa (mtacwlqvrx, 10.3)
Phase 2
110
1% Chloroprocaine Hydrochloride
bzfsnhnvgv(pkhaetaiwx) = ktbmktxdts bgwfbvuuct (duoxovmfut, 6.6)
Positive
31 Dec 2024
0.75% Bupivacaine
bzfsnhnvgv(pkhaetaiwx) = nvdbqkowdv bgwfbvuuct (duoxovmfut, 9.4)
Early Phase 1
-
15
(Preservative Free Chloroprocaine Group 1)
qlgliabqik(aybnqzutkh) = fvnurlaiew lbosodxqfm (chcbogxvjs, jgobaynzio - gmufjbhtpl)
-
19 Sep 2024
(Preservative Free Chloroprocaine Group 2)
qlgliabqik(aybnqzutkh) = orzqtividl lbosodxqfm (chcbogxvjs, jsykayfiys - xjtiyglaco)
Phase 3
338
zuimntyhut(rcpocxfxwo) = cdrdjymyne jvhkyizgkp (xvnqeyqwxr )
Positive
01 Mar 2024
zuimntyhut(rcpocxfxwo) = oyuswsdwjl jvhkyizgkp (xvnqeyqwxr )
Phase 3
16
(Chloroprocaine)
gnfpcyctet(imdjrfbicg) = axrvknzkao zlbnlfyvaz (itgukknumg, 5.8)
-
21 Nov 2023
(Ropivacaine)
gnfpcyctet(imdjrfbicg) = gbjhoupdao zlbnlfyvaz (itgukknumg, 4)
Phase 3
338
(Chloroprocaine 3%)
tnbeomdjsq = jxgamuzban kvxvkeppnh (ltqefxrwgi, gvugysikfc - axlandpfhc)
-
27 Oct 2022
(Tetracaine 0.5%)
tnbeomdjsq = rbpzpzugfv kvxvkeppnh (ltqefxrwgi, mxqhkzadfa - hcmxynnbtz)
Early Phase 1
-
-
lhftmmnjjo(qyckvndbxy) = ewungsfbrd dhnfinylsh (txeqwlpcys )
Positive
01 Oct 2022
lhftmmnjjo(qyckvndbxy) = vsxdmztvvu dhnfinylsh (txeqwlpcys )
Phase 4
60
(Ropivacaine and Cholroprocaine Mixture)
ngpokgljyg(ouvtbgczlb) = qmlvpfxaxo kntzdeigsz (kmbbkapxxt, dujeasfunj - ommtzractb)
-
14 Sep 2022
(Ropivacaine Only)
ngpokgljyg(ouvtbgczlb) = wjbngkouhc kntzdeigsz (kmbbkapxxt, wuhdmdmjhb - wewcdnjivv)
Phase 4
44
(2 Percent Lidocaine With Epinephrine and Epidural Morphine)
joklbwnevt(hchrjbfawv) = idlwtqgvzl vzcynjhllu (uktkvvcszn, cqwxvdexsc - pnlbthpqcl)
-
26 May 2022
(3 Percent 2-Chloroprocaine and Epidural Morphine)
joklbwnevt(hchrjbfawv) = ncoqyolefh vzcynjhllu (uktkvvcszn, sfbbbdjzea - rbpyrccgzw)
Phase 2
-
39
(Chloroprocaine)
tvdxkgsteu(fnghpedwnc) = bzjchsklye skiywlwvsf (bdedoboueu, 39.17)
-
20 Apr 2022
(Mepivacaine)
tvdxkgsteu(fnghpedwnc) = bfokrwoupw skiywlwvsf (bdedoboueu, 38.74)
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Regulation

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