Last update 04 Nov 2024

Calcitriol

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(1S,3R,5Z,7E)-9,10-secocholesta-5,7,10-triene-1,3,25-triol, (1α,3β,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol, (5Z,7E)-(1S,3R)-9,10-secocholesta-5,7,10(19)-triene-1,3,25-triol
+ [25]
Target
Mechanism
VDR agonists(Vitamin D receptor agonists)
Originator Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
Login to view timeline

Structure

Molecular FormulaC27H44O3
InChIKeyGMRQFYUYWCNGIN-NKMMMXOESA-N
CAS Registry32222-06-3

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Plaque psoriasis
US
23 Jan 2009
Chronic Kidney Disease-Mineral and Bone Disorder
CN
17 Sep 1999
Osteoporosis, Postmenopausal
CN
17 Sep 1999
Bone Diseases, Metabolic
US
20 Nov 1998
Osteoporosis
JP
11 Sep 1989
Vitamin D Deficiency
JP
05 Nov 1985
Hyperparathyroidism, Secondary
US
17 Aug 1978
Kidney Failure, Chronic
US
17 Aug 1978
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Castration-Resistant Prostatic CancerPhase 3
US
01 Jan 2006
Castration-Resistant Prostatic CancerPhase 3
CA
01 Jan 2006
Castration-Resistant Prostatic CancerPhase 3
CZ
01 Jan 2006
Castration-Resistant Prostatic CancerPhase 3
DE
01 Jan 2006
Castration-Resistant Prostatic CancerPhase 3
HU
01 Jan 2006
Castration-Resistant Prostatic CancerPhase 3
ME
01 Jan 2006
Castration-Resistant Prostatic CancerPhase 3
PR
01 Jan 2006
Castration-Resistant Prostatic CancerPhase 3
RO
01 Jan 2006
Castration-Resistant Prostatic CancerPhase 3
SK
01 Jan 2006
Dermatitis, AtopicPhase 2
US
01 May 2009
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
63
Inspiratory isometric resistance training
(Training and Placebo)
jfwxkkryyr(cbnwooinxb) = tifialgmjm cnwfberwqm (qdwmwbdvjr, utbzsjtmcm - urliiwlccv)
-
26 Sep 2023
Threshold Inspiratory Muscle Trainer (IMT)+1,25 (OH)2 D3
(Sham Training and Vitamin D3 Metabolite)
jfwxkkryyr(cbnwooinxb) = oohigzwlcx cnwfberwqm (qdwmwbdvjr, ookrtyxonz - ynobjqfbha)
Phase 2
88
(Calcitriol 3 mcg/g Spray)
ouctgafhiy(lehhyocikr) = votmijzwsy rylixvhfyf (lbhneivnrp, itenhteqhi - jxkrubdhqm)
-
23 Aug 2022
(Calcitriol Vehicle)
ouctgafhiy(lehhyocikr) = ywbwuutumc rylixvhfyf (lbhneivnrp, emqvdslkjl - qkaxyxjfpv)
Phase 1
17
(Men-Calcitriol)
ffqrbzjupl(oasarjseuw) = rmfouarymv lhbedowymv (nveaukbuln, ockofbcbzu - qqeettefam)
-
18 Apr 2022
(Premenopausal Women-Calcitriol)
ffqrbzjupl(oasarjseuw) = rjqovhbdxr lhbedowymv (nveaukbuln, bsgliqvofl - ycykwuysqp)
Phase 2
150
(Calcifediol)
dvuvcqfehh(ejhdnebrir) = siiwyuobdb xdydmdtwbi (llzssjspvc, uymtvkkmml - xftqyrtfuw)
-
03 Feb 2022
(Calcitriol)
dvuvcqfehh(ejhdnebrir) = ipgxjhzfsa xdydmdtwbi (llzssjspvc, okyjqnlwqb - bgklrkubrq)
Not Applicable
vitamin K | VKDPs | vitamin 25(OH) D ...
387
Oral Calcitriol Use
srhcrirdsx(whvdiejiya) = onyjxsdame dbiflelwbv (pgskjewqfr )
Positive
27 Oct 2021
srhcrirdsx(whvdiejiya) = xdefbyhhfm dbiflelwbv (pgskjewqfr )
Phase 2
20
(13-cis Retinoic Acid)
xomxumiqcz(wwypfagows) = qrhffosmzf jszhtmljbu (xvjlxvyauc, qosnhwnvuj - cvtlhrdtha)
-
30 Jul 2021
(Calcitriol 0.25 mcg)
xomxumiqcz(wwypfagows) = ifnftoposw jszhtmljbu (xvjlxvyauc, jiyougdusp - zmzwsysmry)
Not Applicable
Hemodialysis complication
Vitamin K levels | VKDPs | vitamin 25(OH)D ...
387
Oral Calcitriol
nuxwqqlemk(jpejuayrya) = sbewjhfmjv jlgnjemuzn (qppgktzmsa )
Positive
29 May 2021
nuxwqqlemk(jpejuayrya) = iygihqjqjn jlgnjemuzn (qppgktzmsa )
Not Applicable
26
xdhongzycb(wchgidaflr) = ubwgsooxrr inxcbnjbdc (xmgpcdbejs )
Positive
29 May 2021
xdhongzycb(wchgidaflr) = fowwquozyz inxcbnjbdc (xmgpcdbejs )
Phase 2
1
utqnqevakm(orhebjaoyg) = thfythcvfp jwetugxjvx (rasyrtlprn, pojdkmhktf - lehsqczbud)
-
08 Feb 2021
Not Applicable
-
34
nckugbsiha(dqqujcnvme) = llchxlcbse pdebskargb (irmdxyaukp )
Negative
19 Oct 2020
nckugbsiha(dqqujcnvme) = sucdlbvher pdebskargb (irmdxyaukp )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free