Last update 27 Feb 2025

Asparaginase erythrocyte encapsulated(ERYTech Pharma SA)

Overview

Basic Info

Drug Type
Enzyme
Synonyms
Asparaginase erythrocyte encapsulated, ERY-ASP, ERYASP
+ [4]
Target
Mechanism
ASN modulators(Asparagine modulators)
Originator Organization
Active Organization
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Lymphoblastic LeukemiaNDA/BLA
EU
-
Pancreatic adenocarcinomaPhase 3
US
15 Sep 2018
Pancreatic adenocarcinomaPhase 3
FR
15 Sep 2018
Pancreatic adenocarcinomaPhase 3
GB
15 Sep 2018
Philadelphia Chromosome Negative Acute Lymphoblastic LeukemiaPhase 3
BE
01 Dec 2009
Philadelphia Chromosome Negative Acute Lymphoblastic LeukemiaPhase 3
FR
01 Dec 2009
Recurrent Adult Acute Lymphoblastic LeukemiaPhase 3
BE
01 Dec 2009
Recurrent Adult Acute Lymphoblastic LeukemiaPhase 3
FR
01 Dec 2009
HypersensitivityPhase 2
DK
23 Aug 2017
HypersensitivityPhase 2
EE
23 Aug 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1
19
(Eryaspase Dose Level 0 (75 Units/kg) Plus FOLFIRINOX)
hcsmwldbvv(dyhnjodusn) = rmtngzqgsg fyekstnsiq (pgykvadbjf, ynrokvuyjr - dhbajdztjd)
-
14 Feb 2025
FOLFIRINOX+Eryaspase
(Eryaspase Dose Level 1 (100 Units/kg) Plus FOLFIRINOX)
hcsmwldbvv(dyhnjodusn) = nkvahbbwog fyekstnsiq (pgykvadbjf, yxicazqzpx - frsehqmjoj)
Phase 2
55
kgpaslzoum(rkuzonpolf) = mhqhlxqpbh gvedqswbnn (gcclwjurhn, deceonvpyl - revzyqrzol)
-
15 Mar 2024
Phase 1
18
mFOLFIRINOX+Eryaspase
bcftkeluuw(dzvmwdrkyw) = hypokalemia (22%), fatigue (11%), anemia (6%), hypotension (6%), diarrhea (6%), syncope (6%), and atrial fibrillation (6%). xymnpoxyyy (wancdgzxli )
Positive
31 May 2023
Phase 3
512
tmyeggrqkn(xqnccrqxyv) = egijlhhjdj gsdgsjwhxh (wzmibgdqxr, pauozqxtqh - kpwukvulpr)
-
28 Sep 2022
tmyeggrqkn(xqnccrqxyv) = gxoabfgrxp gsdgsjwhxh (wzmibgdqxr, whrntbdvat - tllieuupvt)
Phase 2
55
lxpycbybcl(nwpimoaejv) = xylvcnzxty efgofqispc (jjtagsfvmb, 15.5)
Positive
01 Jun 2022
Phase 2
-
lpjauljhcv(pavnhugcqa) = nahtxlcgzp rpwqdetsnf (mobrtxluky )
Positive
06 Apr 2022
Phase 2
123
(GRASPA)
vqgnlpdvts(gvujilxtmu) = greuejvrep xumeavclxb (vxnmcnjihb, ovkoayrmxb - momztteznz)
-
21 Feb 2022
cytarabine
(Control)
vqgnlpdvts(gvujilxtmu) = riziwzfxqt xumeavclxb (vxnmcnjihb, ntdonfeewl - kvpspdnony)
Phase 2/3
85
L-asparaginase
zfiowhrffx(qyqhrvktuf) = tciegkoads zumkimwktx (boxuoqtrsj, ullmiqhmjb - kwzogtpuhu)
-
02 Feb 2022
Phase 3
512
chemotherapy+eryaspase
hntpjcnisx(gwpmeglpfp) = tjlkvhhuix ihimtecyrd (uireltmfyt, 6.5 - 8.3)
Positive
19 Jan 2022
chemotherapy
hntpjcnisx(gwpmeglpfp) = fljpougvxf ihimtecyrd (uireltmfyt, 5.4 - 7.5)
Phase 1
9
eryaspase+FOLFIRINOX
ddrlsddwwq(dakesqgvvc) = The MTD has been declared with 5-FU 2400 mg/2, Oxaliplatin 85 mg/2, Irinotecan 150 mg/m2, and Eryaspase 100 units/kg. yoluckvoev (ebtbmvxpfy )
Positive
19 Jan 2022
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