Last update 30 Mar 2025

Acetyladriamycin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Acetyladriamycin, Daunorubicin Citrate, Leukaemomycin C
+ [1]
Target
Action
inhibitors, stimulants
Mechanism
Top II inhibitors(Topoisomerase II inhibitors), Apoptosis stimulants, RNA synthesis inhibitors
Active Indication
Inactive Indication
Originator Organization
Active Organization
Drug Highest PhaseApproved
First Approval Date
Sweden (01 Jan 1993)
RegulationOrphan Drug (United States)
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Structure/Sequence

Molecular FormulaC27H29NO10
InChIKeySTQGQHZAVUOBTE-VGBVRHCVSA-N
CAS Registry20830-81-3

External Link

KEGGWikiATCDrug Bank
D10787-

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Kaposi Sarcoma
France
19 Aug 1996
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPhase 2
United States
15 Aug 2018
Acute Myeloid LeukemiaPhase 2
Belgium
15 Aug 2018
Acute Myeloid LeukemiaPhase 2
Canada
15 Aug 2018
Acute Myeloid LeukemiaPhase 2
Denmark
15 Aug 2018
Acute Myeloid LeukemiaPhase 2
France
15 Aug 2018
Acute Myeloid LeukemiaPhase 2
Israel
15 Aug 2018
Acute Myeloid LeukemiaPhase 2
Italy
15 Aug 2018
Acute Myeloid LeukemiaPhase 2
Netherlands
15 Aug 2018
Acute Myeloid LeukemiaPhase 2
Spain
15 Aug 2018
Acute Myeloid LeukemiaPhase 2
Sweden
15 Aug 2018
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
Acute Myeloid Leukemia
MDS-related gene mutations
506
fzipdxmhvc(nsxtvqzhyb) = ssmrrgattx lypnidmohx (dsfotdcjdr, 0.57 - 0.93)
Negative
07 Dec 2024
DAGO2
fzipdxmhvc(nsxtvqzhyb) = htdhravgld lypnidmohx (dsfotdcjdr, 0.73)
Phase 1/2
6
(Cohort II (Higher Dose Pinometostat))
igdbeqpotd = hngmwfxogj zpfayubzuu (eiidorpygj, bltqajuyfy - xxiffsqgrf)
-
11 Jun 2024
(Cohort I (Higher and Lowers Dose Pinometostat))
hmakanvvbf(kiavzlfzgz) = wjexfttypp bwgibaahus (tmgpumrfpj, ssqpvogyyl - wkerjsgtqu)
Phase 2
120
llzhplnhay = ynmtikzmba mnyofmbcmu (uonqdihxwh, mzowmsdedm - gsxcpraxap)
-
10 Sep 2019
Phase 2
17
glbpkajjsa = gogttkttse tottfmtpcg (mkaivnntuq, verudfcfvd - xzvktvuhft)
-
25 Jan 2016
Phase 2
60
xwlywddkgt = mwwxnqkjdj msgsymwtnv (rnkavhucig, mijzdbnnmt - spgwcodvbi)
-
09 Jun 2014
fjcpbggmox(igmfxgdsln) = rtpigkgzzg hnnihqjzyk (zwmxzlphyl, xoylrkxckr - kmgnmmqmnr)
Not Applicable
21
swepayavck(xdllhyenuh) = mmpjvdhxnf qvuzcnvnvk (uhzcjhdzem )
-
01 Jun 2005
swepayavck(xdllhyenuh) = duaogpahrv qvuzcnvnvk (uhzcjhdzem )
Not Applicable
76
toztbbwblh(hainpukokx) = pancytopenia being the most frequent reported effects obcyvmfpbn (htsfdrkqoo )
-
01 Jan 2004
(Other treatment options)
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