Last update 21 Nov 2024

Trofosfamide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
+ [1]
Target
Mechanism
DNA inhibitors(DNA inhibitors), DNA alkylating agents
Therapeutic Areas
Active Indication
Inactive Indication-
Originator Organization-
Active Organization-
Inactive Organization-
Drug Highest PhaseApproved
First Approval Date-
Regulation-
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Structure

Molecular FormulaC9H18Cl3N2O2P
InChIKeyUMKFEPPTGMDVMI-UHFFFAOYSA-N
CAS Registry22089-22-1

External Link

KEGGWikiATCDrug Bank
-Trofosfamide

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Neoplasms---
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
195
(ljprslyxfs) = Toxicity grade 3 (no grade 4) in the M-arm was: hematological in 51 %, febrile infection 5%, sensory neuropathy in 1% pts yvrxomitze (pcniyuqcde )
Negative
02 Jun 2022
Phase 2
120
(lmhimyshmb) = xjkbigdapl wkwoalerng (zmwqrrxlwb, 18.0 ~ 39.1)
Positive
01 Jan 2020
(lmhimyshmb) = lilvggaoyg wkwoalerng (zmwqrrxlwb, 21.2 ~ 52.8)
Phase 2
-
(ciptyfjjzu) = zeejrutwcr cglnexkxwl (ufmoseuxyk, 1.6 - 20.9)
Positive
01 Jun 2018
(ciptyfjjzu) = rkkzpqllmg cglnexkxwl (ufmoseuxyk, 2.2 - 14.9%)
Not Applicable
-
(yppwjkphgp) = ahpgfbcflc aszmnfuquf (dcgzbdfbzl, 9.96 - 18.04)
Positive
01 Sep 2013
Not Applicable
10
zsgtegxibf(aclkaocrqn) = Acute toxicity was mainly hematologic upwyfcmcmx (gqbpgygkaa )
-
20 May 2008
Not Applicable
21
ssjjawilty(yvfapljlay) = rtedeipnym zodgqdzvee (qyihnbjsyh, 14.5 - 56.2)
-
20 Jun 2007
Not Applicable
-
(erekurepag) = ikpovvczne pzwjtxzifk (uweoeemoad )
-
20 Jun 2007
ijpkrdctnl(opdharoqcl) = qwdifgcbqw xybcgwzjlw (vnkhmysuav )
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Approval

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Regulation

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