Drug Type Small molecule drug |
Synonyms (glycolato-O,O')diammineplatinum(II), CDGP, cis-Diammine (glycolato)platinum + [11] |
Target |
Mechanism DNA inhibitors(DNA inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Inactive Organization- |
Drug Highest PhaseApproved |
First Approval Date JP (30 Jun 1995), |
RegulationOrphan Drug (US) |
Molecular FormulaC2H8N2O3Pt |
InChIKeyGYAVMUDJCHAASE-UHFFFAOYSA-M |
CAS Registry95734-82-0 |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D01416 | Nedaplatin |
Indication | Country/Location | Organization | Date |
---|---|---|---|
Neoplasms | JP | 05 Sep 1995 | |
Bladder Cancer | JP | 30 Jun 1995 | |
Esophageal Carcinoma | JP | 30 Jun 1995 | |
Head and Neck Neoplasms | JP | 30 Jun 1995 | |
Non-Small Cell Lung Cancer | JP | 30 Jun 1995 | |
Ovarian Cancer | JP | 30 Jun 1995 | |
Small Cell Lung Cancer | JP | 30 Jun 1995 | |
Testicular Neoplasms | JP | 30 Jun 1995 | |
Uterine Cervical Cancer | JP | 30 Jun 1995 |
Phase 2 | 49 | Concurrent nedaplatin plus paclitaxel with radiotherapy | hszjojouuk(zcwnbjvfhl) = ygvhyqvbcg ncynasxnkr (owgawnnynx ) View more | - | 01 Jul 2023 | ||
NCT04834206 (ASCO2023) Manual | Phase 2 | Nasopharyngeal Carcinoma First line | 32 | owppfkjjim(vxoxdthvzp) = gegbnwfato kagzjmlpqk (ugqinrcqga ) View more | Positive | 31 May 2023 | |
Not Applicable | 30 | afgtuwmiga(xjjdpiltnk) = zbvofxfjuy fxdsgntyrb (wjpfofinzg ) | Positive | 21 Sep 2022 | |||
Pubmed Manual | Phase 3 | 160 | radiotherapy+Nedaplatin | qvfntnilau(ykvcchwvqz) = knsrzxmsxm jwphczajul (fldqcjqadp ) View more | Non-inferior | 19 Aug 2022 | |
radiotherapy+Cisplatin | qvfntnilau(ykvcchwvqz) = nvmpqsffmm jwphczajul (fldqcjqadp ) View more | ||||||
Phase 3 | 218 | edxhimaldy(cxqarqooar) = iyaffkanym dknonoihab (ksnjzwrbyb, 5.25 - 8.49) View more | Non-inferior | 02 Jun 2022 | |||
edxhimaldy(cxqarqooar) = cdcnloniil dknonoihab (ksnjzwrbyb, 4.57 - 6.50) View more | |||||||
Not Applicable | 18 | gmlxknznop(ggosgckajq) = vihmagdeek nvszqhyckg (ouchfcjpds ) | - | 25 Sep 2021 | |||
Not Applicable | Esophageal Carcinoma Neoadjuvant | 26 | DNF (Docetaxel, Nedaplatin, 5-FU) | jhxeqkzhli(zfohlbdtda) = 27% asghasrcad (ikkivuwfqa ) View more | - | 03 Jul 2021 | |
Phase 3 | 54 | bulsvilpbl(tjlhvixard) = and grade 1-2 anemia 51.6% vs. 43.5% (P=0.003) janurgcdbr (goaeabwyae ) View more | Negative | 19 Sep 2020 | |||
Not Applicable | 26 | ziseysosez(jarytwrbyg) = ccrbekbije atcgitbbkd (xkfawwsayg ) View more | - | 09 Sep 2019 | |||
Phase 2 | squamous cell lung carcinoma First line | 21 | Nedaplatin plus Amrubicin | bvmtdvgszx(dtfqlyqfeu) = tjineqlfgk kefrssysuk (zaqfoirevm ) View more | Positive | 24 Nov 2018 |