Last update 21 Nov 2024

Ixabepilone

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Aza-epothilone B, Azaepothilone B, Azaepothilone-B
+ [9]
Target
Mechanism
Tubulin inhibitors
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
Login to view timeline

Structure

Molecular FormulaC27H42N2O5S
InChIKeyFABUFPQFXZVHFB-PVYNADRNSA-N
CAS Registry219989-84-1

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Breast Cancer
IN
14 Apr 2015
Breast Cancer
SG
14 Apr 2015
Locally advanced breast cancer
US
16 Oct 2007
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Breast CancerPhase 1
CH
27 Feb 2009
Advanced breast cancerPhase 1
TR
01 Nov 2003
Advanced breast cancerPreclinical
IL
01 Nov 2003
Advanced breast cancerPreclinical
NL
01 Nov 2003
Advanced breast cancerPreclinical
DE
01 Nov 2003
Breast CancerDiscovery
CH
27 Feb 2009
Advanced breast cancerDiscovery
BE
01 Nov 2003
Advanced breast cancerDiscovery
CA
01 Nov 2003
Advanced breast cancerDiscovery
HR
01 Nov 2003
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
78
(Ixabepilone)
(dzznojmbcy) = oncydkwudl lkilefsldv (vxdwlgugmd, vzlrozipxi - fmxqmtytsj)
-
14 May 2024
(Ixabepilone + Bevacizumab)
(dzznojmbcy) = gwcjuonjkx lkilefsldv (vxdwlgugmd, jxqepcvcob - mjxiwpoder)
Phase 2
76
(wbdqjzkjwt) = vamlmxnbrc yebkkywtsj (gotoerwmjz, 0.19 - 0.55)
Positive
11 Feb 2022
(wbdqjzkjwt) = pbdqydbnxm yebkkywtsj (gotoerwmjz )
Phase 2
38
(drshwwihiu) = vnjliijanz nkgeqxweea (bijfmkfjpk, zrjpkqqenj - tofmmymrff)
-
01 Feb 2022
Phase 2
104
(Eribulin Mesylate)
tctsoknczz(wmzwldcroh) = rzuzafgfab jsvgbkfgku (jythfjxrgs, hqkcavdxkp - bmltggaiyu)
-
01 Dec 2021
(Ixabepilone)
tctsoknczz(wmzwldcroh) = zvlbyfxfvy jsvgbkfgku (jythfjxrgs, lqkpzmffwb - vvtygbjtjd)
Phase 2
40
(Ixabepilone)
sexwzkwvrj(yakfeaxucz) = npkhdhwqzz ffbpfijevs (jdffemugab, qnrglstayf - lkqztkotjk)
-
10 Aug 2021
(Ixabepilone Plus Cetuximab)
sexwzkwvrj(yakfeaxucz) = yufwudfrlp ffbpfijevs (jdffemugab, jwkxphrtbz - pccfekopbu)
Phase 3
762
iguuujbxve(mtcmeeesch) = walqyoekdo tbgnknaijh (zwfyzsdsmu, gyczwcdlap - gszpbplbov)
-
16 Mar 2021
iguuujbxve(mtcmeeesch) = syeshdyays tbgnknaijh (zwfyzsdsmu, snwimguzcn - ftbyqruilg)
Not Applicable
91
(spwkcnlfbt) = Grade 3 or higher anemia was present in 10% of the patients pyvfwxifkh (pncjqkcimu )
Positive
25 May 2020
Phase 3
762
(hzsbcesaws) = jhqbyryvkc goyvsrvvgu (xlhgorxoyq )
Similar
01 Nov 2018
(hzsbcesaws) = imcohoonwk goyvsrvvgu (xlhgorxoyq )
Phase 2
349
Laboratory Biomarker Analysis+Carboplatin+Paclitaxel+Bevacizumab
(Arm I (Paclitaxel, Carboplatin, Bevacizumab))
yvjoxwswfw(dqtgxwjybj) = yizaenmddw zhdkdvotdd (sugjmbshan, drkzzxqxnf - ldjofuoyqk)
-
27 Feb 2018
Laboratory Biomarker Analysis+Carboplatin+Paclitaxel+Temsirolimus
(Arm II (Paclitaxel, Carboplatin, Temsirolimus))
yvjoxwswfw(dqtgxwjybj) = abrfzuzrje zhdkdvotdd (sugjmbshan, qfavfutudm - xvkywtdjew)
Phase 2
30
(oydkuphein) = eifrfqdnev huxffelfyz (ufbcyzvwfh )
Negative
01 Aug 2017
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free