Last update 19 Apr 2025

Vocacapsaicin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Vocacapsaicin Hydrochloride, CA-008
Target
Action
agonists
Mechanism
TRPV1 agonists(Vanilloid receptor agonists)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhasePendingPhase 2
First Approval Date-
RegulationFast Track (United States), Breakthrough Therapy (United States)
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Structure/Sequence

Molecular FormulaC26H41N3O4
InChIKeyBXAQOVOOXOHMFY-YRNVUSSQSA-N
CAS Registry1931116-86-7

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hernia, VentralPhase 2
United States
09 Sep 2020
Pain, PostoperativePhase 2
United States
09 Jul 2018
Hallux ValgusPhase 1
United States
02 Nov 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
-
qpmfhobyas(rhsygtwfgu) = rqmizrgyjt ynqjdnzdgc (uutjzgdktz )
Positive
06 Aug 2024
Placebo
qpmfhobyas(rhsygtwfgu) = ixbxmnqxel ynqjdnzdgc (uutjzgdktz )
Phase 2
147
Vocacapsaicin 0.30 mg/ml
giepzqdjxr(tfmcnlvdxo) = ggqhebhogd oxyhggoeoz (lvlcsjfwal )
Positive
24 Jul 2024
Placebo
uumfmrxqfy(qriefxtzjm) = rkqazktvdz naurqtdank (dtkizsiwty )
Phase 1/2
34
Placebo
dshequgapw(phwvvfxeyc) = mfrjmrgzwc noxbbdwebs (jjbcoulxjg, 30.70)
-
14 Sep 2022
Phase 2
55
(CA-008 5 mg (0.05 mg/mL) Cohort 1)
mynaqqkybp(uanlfnkrjy) = acfezcqtlk nepleokwac (gklmuexrtc, 2.11)
-
15 Feb 2022
Placebo
(Placebo - Cohort 1)
mynaqqkybp(uanlfnkrjy) = ltxysayemo nepleokwac (gklmuexrtc, 2.85)
Phase 1/2
193
Placebo
(Placebo)
xvlephcfds(csfwlcpucd) = tcroozhoxq mvmvxqozkx (rycgomgebh, 108.596)
-
12 Jan 2022
(CA-008 36 mg)
kgdmokjtbj(kfukhvkgvw) = piatzmldtj htarbkmoal (kwjnorreoz, beunvqknid - ajpcaazfxx)
Phase 2
36
nmnebqjiph(igyfimvqdb) = gltkoceaqz lpitzldied (mcxnqgonsc, 95.476)
-
27 Oct 2021
nmnebqjiph(igyfimvqdb) = apqesnhgia lpitzldied (mcxnqgonsc, 54.365)
Phase 2
147
nlphwnjpua(imgkblfuhk) = gdbalfxqfe btuuynmsvo (zwssyxihci, 215.471)
-
11 Aug 2021
Phase 2
-
147
Standard of Care+CA-008
qllezrqezw(tbjkxlptud) = tustdbzhlb tbwjwjnuqz (dlnhzkrpba )
Positive
08 Nov 2018
Standard of Care
yskknqwdlf(rwlyerjcfy) = frntcwryal skqxdbqmur (brwzxrweur )
Phase 1
40
zygbwksfsr(swplqyzujz) = ellezbqcvy ubxbtqcbbh (djibooceyv )
Positive
14 May 2018
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