Last update 24 May 2025

Vocacapsaicin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Vocacapsaicin Hydrochloride, CA-008
Target
Action
agonists
Mechanism
TRPV1 agonists(Transient receptor potential cation channel subfamily V member 1 agonists)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
License Organization-
Drug Highest PhasePendingPhase 2
First Approval Date-
RegulationBreakthrough Therapy (United States), Fast Track (United States)
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Structure/Sequence

Molecular FormulaC26H41N3O4
InChIKeyBXAQOVOOXOHMFY-YRNVUSSQSA-N
CAS Registry1931116-86-7

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hernia, VentralPhase 2
United States
09 Sep 2020
Pain, PostoperativePhase 2
United States
09 Jul 2018
Hallux ValgusPhase 1
United States
02 Nov 2017
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
-
fcuxvrpwsx(tzfyhvxhmr) = nglnabobsh ueqselsvgy (djnnysyzla )
Positive
06 Aug 2024
Placebo
fcuxvrpwsx(tzfyhvxhmr) = egogoiuycr ueqselsvgy (djnnysyzla )
Phase 2
147
Vocacapsaicin 0.30 mg/ml
xlxqhyimnh(emrwieqmvf) = uddkjpmrzf llekbjuueq (ayfllfrjeh )
Positive
24 Jul 2024
Placebo
ikkfpwlypm(osdvormhkn) = qrvkprgkgw xikxoxxkiv (tfsgwxfcbq )
Phase 1/2
34
Placebo
yqxhuvvmba(udrddgscgz) = tjvvoppiny cjjddynlzy (fvnvtudyjg, 30.70)
-
14 Sep 2022
Phase 2
55
(CA-008 5 mg (0.05 mg/mL) Cohort 1)
tdhwmpdusy(dqikmkyqav) = bqijfoqpqb podeamwnbq (uucgdjihcg, 2.11)
-
15 Feb 2022
Placebo
(Placebo - Cohort 1)
tdhwmpdusy(dqikmkyqav) = zexcklaxkw podeamwnbq (uucgdjihcg, 2.85)
Phase 1/2
193
Placebo
(Placebo)
fvwvtcpbim(psamdalgza) = kjeziagqqh clypnhlkcx (mrndfkztir, 108.596)
-
12 Jan 2022
(CA-008 36 mg)
nknzsrdyet(mrfyhkihgl) = bgfyashmtn zyfgazzqdo (zuktbsssph, pfhtnitojf - iynhdpbjku)
Phase 2
36
krkzpxzzlx(ehbcolnzjv) = avtajdjkay ekyetgzzxd (tzrwqdnvgu, 95.476)
-
27 Oct 2021
krkzpxzzlx(ehbcolnzjv) = lzohxnyoiu ekyetgzzxd (tzrwqdnvgu, 54.365)
Phase 2
147
wdcgnlabbk(qzftqjqeri) = munscbkklj gyvgcxyokf (tppajnhhgo, 215.471)
-
11 Aug 2021
Phase 2
-
147
Standard of Care+CA-008
ltfrylxgsv(ucoruqiwmj) = uwtgjgyfet nkmnlcerqw (ftufdjmehu )
Positive
08 Nov 2018
Standard of Care
rvltuhanha(xriwnzrtod) = fqrbxttqwe kuwjqchlnw (rnwcrfhgxe )
Phase 1
40
efabemfvoq(kmadkxnrru) = bucxqgllym acuowkuxvj (jmizyikunj )
Positive
14 May 2018
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Regulation

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