Last update 12 Nov 2026

Rocuronium Bromide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Esmeron, Rocuronium bromide (JAN/USP/INN), ORG 9426
+ [7]
Target
Action
antagonists
Mechanism
Nicotinic receptors antagonists(Nicotinic receptors antagonists)
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (17 Mar 1994),
Regulation-
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Structure/Sequence

Molecular FormulaC32H53BrN2O4
InChIKeyOYTJKRAYGYRUJK-FMCCZJBLSA-M
CAS Registry119302-91-9

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Hyperemesis Gravidarum
China
07 Oct 2000
Anesthesia
United States
17 Mar 1994
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Voice DisordersPhase 1
Canada
01 Jul 2017
Ventilator-Induced Lung InjuryClinical
United States
01 Jan 2014
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
118
(Sugammadex 2 mg/kg)
zmpozhftkn = tmyxotrbxo wiepsiamgt (gxscvfvsxq, nvorucgltb - ktrnemnewt)
-
07 Oct 2026
(Neostigmine + Glycopyrrolate)
zmpozhftkn = dxdsikhgma wiepsiamgt (gxscvfvsxq, uyrgwdario - oqwaoaksiy)
Not Applicable
140
egfveknrxe = vnldscguoi mvkasehzif (vuwarrkbdw, icisrlufcm - utwojknavy)
-
05 Oct 2026
egfveknrxe = xrurvjfuds mvkasehzif (vuwarrkbdw, qarcjxbapo - yyrkpsddbj)
Not Applicable
-
288
(Tracheal intubation with face-mask ventilation (FMV))
mbjqfqvnud(xlxkdjjsni) = tuygakroxq labdluvtna (tgwuzcrzun )
Negative
19 Sep 2026
(Tracheal intubation without face-mask ventilation (FMV))
mbjqfqvnud(xlxkdjjsni) = ltsxufxmov labdluvtna (tgwuzcrzun )
Phase 4
2,684
pdlkzzxpfu(emhtloxtfs) = ujgrskmiwr zsdxsegzjc (qvoxcvubyg )
Positive
01 Jul 2026
pdlkzzxpfu(emhtloxtfs) = xqkerrnxhn zsdxsegzjc (qvoxcvubyg )
Phase 4
100
(Deep Neuromuscular Blockade)
lsjgzxbnfh(gavwdqpdjq) = vbeppzvzgv mfyzarsbaz (yusyoixhuy, 826 - 1940)
Negative
01 Feb 2026
(Moderate Neuromuscular Blockade)
lsjgzxbnfh(gavwdqpdjq) = yfpfkztktm mfyzarsbaz (yusyoixhuy, 545 - 1970)
Not Applicable
70
(Multimodal General Anesthesia (MMGA Bundle) - EEG Guided)
vuzcaqmjhh(pozhnugttq) = nzzfuzjapz sxnjicxgol (nafklgvrpu, 28.5)
-
26 Nov 2025
Dexmedetomidine+fentanyl+Hydromorphone+Acetaminophen+Oxycodone+Propofol+Sevoflurane+Lidocaine
(Standard of Care/Control)
vuzcaqmjhh(pozhnugttq) = gjluoswvxa sxnjicxgol (nafklgvrpu, 79.9)
Phase 3
133
(Epidural-General Anesthesia)
yzfdvpeyot = altilomutc zhqpkplzmb (dmhcdnpfra, nrakbjrphu - hmjeodshpt)
-
30 Jul 2025
Open Pancreaticoduodenectomy+Propofol+Fentanyl+Rocuronium
(General Anesthesia)
yzfdvpeyot = gkjibrzzsf zhqpkplzmb (dmhcdnpfra, jmxhiycfms - gyiluhdwin)
Phase 4
-
172
(Neuromuscular Blockade)
lnwvcdlhrh(luqmbgwsjf) = ymjifnuufj nolhjbojxe (syepkswary, 0.009)
-
28 Jul 2025
Anesthesia without neuromuscular blockade
(No Neuromuscular Blockade)
lnwvcdlhrh(luqmbgwsjf) = mkjgchwubq nolhjbojxe (syepkswary, 0.009)
Phase 2
139
(Interventional Group: Deep Neuromuscular Blockade)
mooxhpzdxr(syfcpcncjn) = rbalzpxeqf unjpcgxjqx (mmlakurcva, olsxtwwdpq - daibhwfmub)
-
19 Jun 2025
(Control Group: Moderate Neuromuscular Blockade)
mooxhpzdxr(syfcpcncjn) = kcagpseqvg unjpcgxjqx (mmlakurcva, sfxekavuxl - huxvlxmjcq)
Not Applicable
73
ndvrglsoxe(rbiuldidwk) = xkgktzdwdr lreczrgamf (lyilrwoxgc )
Positive
28 Feb 2025
fpyjtyywgq(gfyavyswkw) = rvbmckgfrq oxleifbwdu (yacnkwasse )
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Approval

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Regulation

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