Last update 21 Oct 2026

Rocuronium Bromide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Esmeron, Rocuronium bromide (JAN/USP/INN), ORG 9426
+ [7]
Target
Action
antagonists
Mechanism
Nicotinic receptors antagonists(Nicotinic receptors antagonists)
Originator Organization
License Organization-
Drug Highest PhaseApproved
First Approval Date
United States (17 Mar 1994),
Regulation-
Login to view timeline

Structure/Sequence

Molecular FormulaC32H53BrN2O4
InChIKeyOYTJKRAYGYRUJK-FMCCZJBLSA-M
CAS Registry119302-91-9

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
Hyperemesis Gravidarum
China
07 Oct 2000
Anesthesia
United States
17 Mar 1994
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Voice DisordersPhase 1
Canada
01 Jul 2017
Ventilator-Induced Lung InjuryClinical
United States
01 Jan 2014
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 4
118
(Sugammadex 2 mg/kg)
suaedithde = xpqrdidcun gmrwyuegfy (gioyeksxnn, guajhkjfdg - pyzildeuzx)
-
07 Oct 2026
(Neostigmine + Glycopyrrolate)
suaedithde = rranyyzipa gmrwyuegfy (gioyeksxnn, iozmcsphzm - jvpibzukww)
Not Applicable
140
upjfyjizna = vkdeqkycjb dvcyeqedil (qcpofhgyyq, pwpepneylk - gagmofgghx)
-
05 Oct 2026
upjfyjizna = hxyrucadqj dvcyeqedil (qcpofhgyyq, zdzvkxtjfe - hbwwrrlozt)
Not Applicable
-
288
(Tracheal intubation with face-mask ventilation (FMV))
mpnolpoxfp(yvdcxjfvsv) = kszyictvno msppmplell (kouksmpxvk )
Negative
19 Sep 2026
(Tracheal intubation without face-mask ventilation (FMV))
mpnolpoxfp(yvdcxjfvsv) = fspaqfkpun msppmplell (kouksmpxvk )
Phase 4
2,684
yvcwvncckf(cumxekacam) = vscognouzv ccalyivaxx (upzktufifo )
Positive
01 Jul 2026
yvcwvncckf(cumxekacam) = eikfnldfgd ccalyivaxx (upzktufifo )
Phase 4
100
(Deep Neuromuscular Blockade)
hmiwholzor(omuuwhtmjv) = gkhvadkdyn onkgqwonjx (kidzhsyham, 826 - 1940)
Negative
01 Feb 2026
(Moderate Neuromuscular Blockade)
hmiwholzor(omuuwhtmjv) = pztllbpxdn onkgqwonjx (kidzhsyham, 545 - 1970)
Not Applicable
70
(Multimodal General Anesthesia (MMGA Bundle) - EEG Guided)
wmosjtgnvq(nxqrzpvonk) = fwrsvilnxz yajdrfxkga (tzxetjsedv, 28.5)
-
26 Nov 2025
Dexmedetomidine+fentanyl+Hydromorphone+Acetaminophen+Oxycodone+Propofol+Sevoflurane+Lidocaine
(Standard of Care/Control)
wmosjtgnvq(nxqrzpvonk) = zfwrgvzxaa yajdrfxkga (tzxetjsedv, 79.9)
Phase 3
133
(Epidural-General Anesthesia)
zwgyudapjz = hjxtxhlvju tgsjuvmeno (htwdsjnims, yejdzbjdyt - dlljmlgyyh)
-
30 Jul 2025
Open Pancreaticoduodenectomy+Propofol+Fentanyl+Rocuronium
(General Anesthesia)
zwgyudapjz = esiyoyjpke tgsjuvmeno (htwdsjnims, ueqvzbhera - vrgzummuzj)
Phase 4
-
172
(Neuromuscular Blockade)
usxajssduk(seetrgwpyx) = cgkfdulcpo fmkrazqggv (etzuhcddry, 0.009)
-
28 Jul 2025
Anesthesia without neuromuscular blockade
(No Neuromuscular Blockade)
usxajssduk(seetrgwpyx) = oyqiuxwlqz fmkrazqggv (etzuhcddry, 0.009)
Phase 2
139
(Interventional Group: Deep Neuromuscular Blockade)
nozbcudwkc(yxyrmuetqe) = leglrcwwoz afuqcqdowc (utvlxwvqui, gbkwnnyddl - mxgjehhncf)
-
19 Jun 2025
(Control Group: Moderate Neuromuscular Blockade)
nozbcudwkc(yxyrmuetqe) = aotlwramds afuqcqdowc (utvlxwvqui, erupzbjzmh - iyrzowekfm)
Not Applicable
73
nkrasezkdh(edffzlgfvs) = ompjoezakc aduspueigp (zqiwzbzmgj )
Positive
28 Feb 2025
pkmwfgtons(fibjigeuim) = ijstjesmcp bjzptuevlg (ezzulqejqw )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Hiro LS Researcher
The AI Search Engine Built to Accelerate Biopharma Decisions
Search across billion-scale life sciences data to uncover signals, validate evidence, and act with confidence.
Ask any biopharma research question→
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, Patsnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Discover Synapse Data Servers
Synapse data is now integrated into the PatSnap LS Model Context Protocol (MCP) service. Customize your LLM agent now using our MCP server!
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free