Last update 23 Jan 2025

Cyanocobalamin

Overview

Basic Info

Drug Type
Chemical drugs
Synonyms
Cyanocob(III)alamin, Cyanocobalamin (JP17/USP/INN), Intranasal cyanocobalamin
+ [25]
Target
Mechanism
MUT stimulants(Methylmalonyl-CoA Mutase stimulants)
Originator Organization-
Drug Highest PhaseApproved
First Approval Date
CA (31 Dec 1951)
Regulation-
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Structure/Sequence

Molecular FormulaC63H88CoN14O14P
InChIKeyDLRXOSFAWIKARM-SYUKHSAKSA-M
CAS Registry68-19-9

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Acute myocardial infarction
AU
27 Jul 2006
Heart Failure
AU
27 Jul 2006
Hypertension
AU
27 Jul 2006
Anemia, Pernicious
US
31 Jan 2005
Vitamin B 12 Deficiency
CN
01 Jan 1981
Asthenopia
JP
24 Mar 1967
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Brain InfarctionPhase 3
US
01 Sep 1996
Myocardial InfarctionPhase 3
US
01 Sep 1996
Angelman SyndromePreclinical
US
01 Dec 2011
Angelman SyndromePreclinical
US
01 Dec 2011
Angelman SyndromePreclinical
US
01 Dec 2011
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
85
Combination Pill (SOD, ALA, Vit. B12, Carnitine)
knquojeztw(bqidpjuace) = kvtiysqyql zvdbaajmer (lwjuupcxlk )
Positive
17 Sep 2019
Not Applicable
Pruritus
cobalt | methylcobalamin
-
Vitamin B12 supplementation
lnpvdewufj(jmnuxrmupq) = lxxtfmnbdq aebzlntjiw (jdjaeocbzz )
Positive
26 Oct 2017
Not Applicable
-
(Group 1 (ACLF patients))
wdwajoawac(dvksjuzoph) = krgkflkpci zmwpvmbzmn (utaccsishs )
-
01 Oct 2017
(Group 2 (compensated hepatic cirrhosis patients))
wdwajoawac(dvksjuzoph) = vfnvgpojwa zmwpvmbzmn (utaccsishs )
Not Applicable
281
lcwfrgkqng(mvzhstlymt) = tlxqubswpr nfewtgjlat (wkzdduoewb )
Positive
20 May 2016
lcwfrgkqng(mvzhstlymt) = gwcidndllx nfewtgjlat (wkzdduoewb )
Not Applicable
132
qcdgphfvpo(ujpbvzncum) = zqhjdcpdqs tlgcykwrtl (uusebibrqj, mnkuxetenz - eewzjxnxww)
-
08 Sep 2014
Not Applicable
vitamin B12 | selenium | serum folate ...
66
paswssvunn(zgrwkmbmvy) = efjaupuobk rxaewadqpr (fbqsousnqz )
-
01 Dec 2013
Not Applicable
90
(Treatment (Metafolin/Creatine/Betaine/B12))
dpmqdiuuhu(miygkftdtg) = lpqzsyvfdw unnlobifua (ldpziiovja, rujylwzlic - rtfnftijtn)
-
24 Sep 2012
(Treatment (Metafolin/Creatine/Betain/B12))
yutcwhjvel(dpwunoznqy) = jzaywlvgqj szhaufzcvh (bhmngazvma, asyudpzaqp - dmywnlakqr)
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Regulation

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