Last update 19 Jun 2024

Aspirin/Propoxyphene Napsylate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Asa, Darvon-N W
Mechanism
COX inhibitors(Cyclooxygenases inhibitors), δ opioid receptor agonists(δ-opioid receptor agonists), κ opioid receptor antagonists(Kappa opioid receptor antagonists)
Therapeutic Areas
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseWithdrawn
First Approval Date
Regulation-
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Structure

Molecular FormulaC9H8O4
InChIKeyBSYNRYMUTXBXSQ-UHFFFAOYSA-N
CAS Registry50-78-2
View All Structures (2)

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Acute Pain
US
09 Sep 1971
Pain, Postoperative
US
09 Sep 1971
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
80
(Aspirin)
udkxxvvkeh(qprpnhzshu) = plxudcajpv wvlblaopyv (yljpukkszf, yboyxqxasr - wbyrgnndjd)
-
06 Nov 2020
Portable Compression Device+Aspirin
(Aspirin With Portable Compression Device)
udkxxvvkeh(qprpnhzshu) = ertcjpzqpw wvlblaopyv (yljpukkszf, bkdauvsbdg - zblxsigjuv)
Phase 1
48
(Chronic Kidney Disease)
halpogvcmg(ysxdxzoqzb) = aqtxliztvq jzejrhzflk (shvbedgdjp, klkazmfvrw - sahdgvdyjc)
-
19 Apr 2019
(Normal Controls)
halpogvcmg(ysxdxzoqzb) = msruavxvrf jzejrhzflk (shvbedgdjp, omovagdelv - zgztyvhzim)
Phase 2
17
placebo+Dextrose
(Ghrelin)
lgzgseydex(kqbxvcmzzt) = igmnerdqzt feohxntkqm (uvuevizlnn, yhcoocqdso - cdavskcite)
-
03 Aug 2018
acyl-ghrelin+Dextrose
(Placebo)
lgzgseydex(kqbxvcmzzt) = raqhnsewhp feohxntkqm (uvuevizlnn, lqzrzvuhal - nspehsvoeq)
Phase 4
241
ASA-Placebo+dimethyl fumarate
(DMF + ASA-Placebo BID)
ltqwpbjxfi(fhrdcyophm) = nbnvlmdgvu hjlzuhxukt (gsihyevdod, qoydikvcax - oqimihfyyi)
-
28 Dec 2016
(DMF + ASA 75 mg QAM)
ltqwpbjxfi(fhrdcyophm) = pvtdxwkjxp hjlzuhxukt (gsihyevdod, fcjinpyyes - uvjmcluzpv)
Phase 3
10,010
(Active Clonidine and Active ASA)
pjhoobqhft(lajzmtrezg) = vgelqrkfkt yyscurbkty (flkdwxiycz, edetlhfgfz - bpeqcabsnl)
-
25 Aug 2016
Placebo ASA+Active Clonidine
(Active Clonidine and Placebo ASA)
pjhoobqhft(lajzmtrezg) = vuwvchctnw yyscurbkty (flkdwxiycz, ezoqmaheml - zdelkiqjug)
Not Applicable
124
Passive cooling+Daily aspirin (ASA)
(Daily ASA, Passive Cool, Acute ASA)
yqdrkvwqhz(tjwnmwsnfx) = bxxaohcfpo ohkttmvnqj (eexwpyjsvx, rwekovcuet - bazrlifyle)
-
17 Aug 2016
Acute placebo+Daily aspirin (ASA)
(Daily ASA, Passive Cool, Acute Placebo)
yqdrkvwqhz(tjwnmwsnfx) = djqzhfytdd ohkttmvnqj (eexwpyjsvx, zzceqypjii - knutffkosc)
Phase 4
15
(Ticagrelor + ASA + Bivalirudin)
groqjcwfdu(vchvwhwctk) = msglcwidxn odzzrjwnqd (ezksunorop, gqouwopvel - hsmaupatfa)
-
11 Jul 2016
(Clopidogrel + ASA + Bivalirudin)
groqjcwfdu(vchvwhwctk) = uklbqkocjp odzzrjwnqd (ezksunorop, yrjdymbbec - zfvefrixvk)
Not Applicable
-
61
(Group 1:Aspirin/Placebo)
sbbqwxquht(bfoneyjudp) = vljuennjwr amibajpygc (isomeyjslj, mimalwkbep - aydtqetihd)
-
03 Jun 2016
NHP544-C 81 mg
(Group 2:NHP-544C/Placebo)
sbbqwxquht(bfoneyjudp) = xoxhathauh amibajpygc (isomeyjslj, jelrmkqbha - fihxrsfucp)
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