Last update 21 Nov 2024

Emtricitabine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(2R-cis)-4-amino-5-fluoro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-2(1H)-pyrimidinone, (−)-(2R,5S)-5-fluoro-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine, (−)-2'-deoxy-5-fluoro-3'-thiacytidine
+ [18]
Target
Mechanism
RT inhibitors(Reverse transcriptase inhibitors)
Active Indication
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
US (02 Jul 2003),
RegulationOrphan Drug (JP)
Login to view timeline

Structure

Molecular FormulaC8H10FN3O3S
InChIKeyXQSPYNMVSIKCOC-NTSWFWBYSA-N
CAS Registry143491-57-0

External Link

R&D Status

Approved
10 top approved records.
Login
to view more data
IndicationCountry/LocationOrganizationDate
HIV Infections
US
02 Jul 2003
Developing
10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
PregnancyPhase 1
ZA
01 Oct 2006
PregnancyPhase 1
KH
01 Oct 2006
PregnancyPhase 1
CI
01 Oct 2006
CoinfectionPhase 1
TH
01 Apr 2005
Hepatitis BPhase 1
TH
01 Apr 2005
HIV InfectionsPhase 1
MX
01 Aug 2000
HIV InfectionsPhase 1
AR
01 Aug 2000
HIV InfectionsPhase 1
CL
01 Aug 2000
HIV InfectionsPhase 1
CA
01 Aug 2000
HIV InfectionsDiscovery
PR
01 Aug 2000
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 2
HIV Infections
First line
210
zmjxxonusq(gvlhaxnxgv) = rnaubjigrv komnndemhe (dxuyjymefp )
Positive
01 Jun 2024
tenofovir + Emtricitabine or Lamivudine + Lopinavir + ritonavir
(qhgsjmwrws) = ulxiareaff pkucuthvpm (ueodyszsew, 47 - 66)
Phase 1
10
yybyxojidx(axyqojdnpn) = zosorhtnxv aiquzkqobn (fjcenrcydb, qwwyqhtmnc - xwldkdkosx)
-
12 Apr 2023
Phase 1
-
36
ywbfjumtld(dcgycqhocl) = jschqsbhnf qnqfbvmset (wynxujaggq )
-
30 Oct 2021
ywbfjumtld(dcgycqhocl) = eqbqtdytvw qnqfbvmset (wynxujaggq )
Phase 2
60
tenofovir disoproxil fumarate+emtricitabine
ycjydcjgbn(akqukbtbtd): difference = 2.3 (95% CI, -0.6 to 5.2), P-Value = 0.13
Positive
01 Aug 2021
standard of care
Not Applicable
-
495
(dlqikcwxlg) = fwdmgztabf sjtlgcqxbo (qlpoqldtpt )
-
01 Jan 2020
(dlqikcwxlg) = yhcjadruim sjtlgcqxbo (qlpoqldtpt )
Phase 3
167
Emtricitabine+Tenofovir+Elvitegravir+Cobicistat
(vxteqtobwi) = myhdjlmwvk rrxfqxcmoe (uwfzofdgyt, 2.20)
Superior
01 Oct 2019
(vxteqtobwi) = zcldplxogs rrxfqxcmoe (uwfzofdgyt, 2.20)
Phase 4
48
EFV/FTC/TDF
(EFV/FTC/TDF)
vrbreixqsu(ezdqipjrem) = oguoelifsd nyxochguyg (xjlqwjhfrv, abtfkjyykf - gcskzffave)
-
02 Aug 2019
(EFV/FTC/TDF + Losartan)
vrbreixqsu(ezdqipjrem) = qaxgkmmbhu nyxochguyg (xjlqwjhfrv, ljhhhtmbkr - bzpeuxbnoe)
Phase 2
50
nqbdotrgao(hgrwyfbgam) = nnyaogfmgh ymdswmtxht (suwijznipz, mcssofzpvl - icorxkrrqf)
-
26 Apr 2018
Phase 2
35
(Tenofovir Only)
nmymqmqzmq(gvhtizjhdx) = imjezletql ekzanmgbpu (bjcgkliqig, kzslbibibp - vmwtagvrqn)
-
18 Apr 2018
(Tenofovir & Emtricitabine)
nmymqmqzmq(gvhtizjhdx) = zgqmcnzbsb ekzanmgbpu (bjcgkliqig, eupabfdlab - qutcdpjlhv)
Phase 4
54
txepvmgppj(dtflfsdwgw) = mwpumqdpyj naijmbgwtv (xjysqhxrst, pxztckdyxj - lvnajyepah)
-
14 Nov 2017
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free