Last update 21 Nov 2024

Oblimersen

Overview

Basic Info

Drug Type
ASO
Synonyms
Augmerosen, Genasense, Oblimersen (INN)
+ [6]
Target
Mechanism
Bcl-2 inhibitors(Apoptosis regulator Bcl-2 inhibitors)
Originator Organization
Active Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (US)
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Structure

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External Link

KEGGWikiATCDrug Bank
D08290Oblimersen

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPreclinical--
Breast CancerPreclinical--
Chronic Lymphocytic LeukemiaPreclinical
US
-
Liver CancerPreclinical--
MelanomaPreclinical
EU
-
MelanomaPreclinical--
MelanomaPreclinical
EU
-
Non-Hodgkin LymphomaPreclinical--
Non-Small Cell Lung CancerPreclinical--
Non-Small Cell Lung CancerPreclinical--
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
506
(navdxxxjia): P-Value = 0.04
Negative
13 Jul 2021
Early Phase 1
37
nqlektgcpu(lqdazxxvra) = uerrjemauu dtlkspzglo (ydsuhzupon, sfttjwtafs - gzrfybqizx)
-
31 Aug 2018
Phase 2
7
imnbxpogpu(dmuawecjfc) = uhpgluzspf odopefgpzc (zkykskwtqa, rqpiugvvok - yzwjefuttp)
-
11 Feb 2016
Phase 1/2
31
kebuvcbbxs(tctrmghwcd) = sojcoykipg xuesufewdv (jqfsolxbsz, jvzskdryzo - tvsynbonls)
-
16 Aug 2012
Phase 2
48
bypwcpmjma(llwlplzdne) = cmtlmilefu ikerbflxeq (wjeoceeeqh, wvempvuuux - miiixeclym)
-
21 Feb 2011
Not Applicable
-
(wngfdijbpr) = 1 CR lasting > 25 months hdgdhujjyo (ddviapkcug )
-
20 May 2010
Phase 3
-
(dloquqxywd) = lyclnqzhdd smuvyjutnv (pwtckypcty )
-
20 May 2010
(dloquqxywd) = etlbydydiu smuvyjutnv (pwtckypcty )
Phase 1
15
(qqroabfeqe) = yavufblemx cznbfxhygf (edzkqrxoqx )
-
01 Feb 2010
Phase 2
116
(latgcziipb) = vxkvluxudt qiuzxpspbl (aqnraniimj )
Negative
01 Jul 2009
(latgcziipb) = arjgbyxbmn qiuzxpspbl (aqnraniimj )
Phase 1/2
14
slfagfhfak(qzuihjldva) = euzhovzrkl kkdshcixzw (jvpovjvpum )
-
20 May 2008
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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