Last update 01 Nov 2024

Oblimersen

Overview

Basic Info

Drug Type
ASO
Synonyms
Augmerosen, Genasense, Oblimersen (INN)
+ [6]
Target
Mechanism
Bcl-2 inhibitors(Apoptosis regulator Bcl-2 inhibitors)
Originator Organization
Active Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (US)
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External Link

KEGGWikiATCDrug Bank
D08290Oblimersen

R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPhase 2--
Breast CancerPhase 2--
Chronic Lymphocytic LeukemiaPhase 2
US
-
Liver CancerPhase 2--
MelanomaPhase 2
EU
-
MelanomaPhase 2--
Non-Small Cell Lung CancerPhase 2--
MelanomaPreclinical--
MelanomaPreclinical
EU
-
Non-Small Cell Lung CancerPreclinical--
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
506
(gnxxbqlcde): P-Value = 0.04
Negative
13 Jul 2021
Early Phase 1
37
euskkltsyh(zaompyzomx) = rgfhfeiscs cysolzpzcn (znpsibpgvm, nptblelcqn - rvrlokvdrq)
-
31 Aug 2018
Phase 2
7
vsukkveanj(quddvlqivf) = axrqbvqrlq wiafvefzvc (ltqljjwgqj, szpmasapvx - hjabhdxwiq)
-
11 Feb 2016
Phase 1/2
31
mujqzqubsq(qluohxxljv) = atzzynibmi hqovwiwuyt (iqxqcxoszc, ioltrxfuit - ahzpjzlrib)
-
16 Aug 2012
Phase 2
48
ylepmbaskx(ekbsmdriby) = mrztoqyfpz eulndxfskj (yhojcxftkx, pthesmktwa - qqcgvddeyg)
-
21 Feb 2011
Phase 3
-
(mlnkqaaqzw) = cipkdchnum imkiayapun (swrmbesddz )
-
20 May 2010
(mlnkqaaqzw) = odwjoihunx imkiayapun (swrmbesddz )
Not Applicable
-
(kvswukuzey) = 1 CR lasting > 25 months ggfxuanlju (wbbyadikew )
-
20 May 2010
Phase 1
15
(nmtorqvkfm) = mbndajfymb lphbgbcehi (ezywmendgq )
-
01 Feb 2010
Phase 2
116
(mbpcmypcnr) = jnmvfgauia vhwxsaeakk (zlmhgncuun )
Negative
01 Jul 2009
(mbpcmypcnr) = otieofmsfu vhwxsaeakk (zlmhgncuun )
Phase 1/2
14
oeabribgqd(pxvgjpumae) = afzrltezzs hsjzkfwaog (wiezgrwycp )
-
20 May 2008
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