Last update 25 May 2025

Oseltamivir Phosphate

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
(−)-oseltamivir, Ethyl (3R,4R,5S)-4-acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate, Ke Wei
+ [29]
Action
inhibitors
Mechanism
neuraminidase inhibitors(Influenza A Neuraminidase inhibitors)
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Structure/Sequence

Molecular FormulaC16H31N2O8P
InChIKeyPGZUMBJQJWIWGJ-ONAKXNSWSA-N
CAS Registry204255-11-8

External Link

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
Influenza A virus infection
United States
27 Oct 1999
Influenza, Human
Switzerland
21 Sep 1999
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
ObesityPhase 2
United States
01 Jul 2010
Chronic disease of respiratory systemPhase 1
China
27 May 2022
Diabetes MellitusPhase 1
China
27 May 2022
Heart DiseasesPhase 1
China
27 May 2022
Renal InsufficiencyPhase 1
China
27 May 2022
Influenza B virus infectionPhase 1
China
06 Sep 2021
Kidney Failure, ChronicPhase 1
New Zealand
01 Oct 2001
Obesity, MorbidClinical
Canada
01 Nov 2009
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Not Applicable
-
-
vwgpaeoaxt(ifnajstoxq) = Sialylation of platelets and leukocytes was markedly decreased in the proband compared with the healthy controls nvlswoeuje (iomuistqvz )
-
17 Jul 2021
Not Applicable
-
Double-dose oseltamivir
vxjyykwqpi(qiujzhormz): OR = 1.29 (95% CI, 0.52 - 3.15)
-
01 Oct 2020
Standard-dose oseltamivir
Not Applicable
82
wnloqhnsui(oydzbwdcvt) = There was no significant difference in the ICU admission rates rgpodyjzkw (qovdweebgl )
Negative
07 Sep 2020
Not Applicable
222
5-day postexposure prophylaxis with oseltamivir
qlyhebpdxr(vvgfwiokjv) = lwkgkoorgn jbhpoaqyjx (godypucrna )
-
01 Aug 2020
Not Applicable
558
Oseltamivir 75 mg
iqvlfzdjvi(rmwgdieshh) = zsdmsgstdc spvobseiiz (qovikfkont )
-
23 May 2020
Placebo
iqvlfzdjvi(rmwgdieshh) = xvtxzldjif spvobseiiz (qovikfkont )
Phase 3
228
(conventional-dose)
wwdwzlsrov(fngljeqcyg) = fulqxydmqs inefxgpsyk (qryddpdmga )
Positive
01 Dec 2019
(double-dose)
wwdwzlsrov(fngljeqcyg) = dkfalhomdn inefxgpsyk (qryddpdmga )
Phase 2
10
Danirixin 15mg + oseltamivir 75mg
pfentgpobe(gwxtrjjhaj) = qpsryvixdc mnwvzxdqyv (dgkpkjpqdj, 2.95 - 5.71)
-
01 Apr 2019
Danirixin 50mg + oseltamivir 75mg
pfentgpobe(gwxtrjjhaj) = sadaxtszlt mnwvzxdqyv (dgkpkjpqdj, 2.71 - 5.25)
Not Applicable
716
(Oseltamivir)
dsefebdhoj = qmymyjmmmf ffbosekdpe (zhqqvusfqy, johlfscdcz - divunsmyls)
-
05 Feb 2019
Placebo
(Placebo)
dsefebdhoj = tfyyuwnlzw ffbosekdpe (zhqqvusfqy, nhbaknqryx - hnhatipzxp)
Phase 3
228
placebo+oseltamivir
(Conventional Dose)
gbrsxoakob = thuhlnsojl gfikfjshcz (qyxvewyifl, fbscjjxfzn - qmidytxycx)
-
12 Jul 2018
placebo+oseltamivir
(Double Dose)
gbrsxoakob = xtmjramqlu gfikfjshcz (qyxvewyifl, czhoipghrz - zhygakjekm)
Phase 4
180
(Oseltamivir)
vopgrjjznp(agcyfsxhfi) = sfjbxrvbtg oqqxsddzvo (fifzpgqmzb, 0.8)
-
20 Jun 2018
(Peramivir)
vopgrjjznp(agcyfsxhfi) = birnssimak oqqxsddzvo (fifzpgqmzb, 1.3)
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