Last update 20 Mar 2025

Meperidine Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Isonipecaïne, Meperidine hydrochloride (USP), Pethidine
+ [8]
Action
agonists
Mechanism
Opioid receptors agonists(Opioid receptors agonists)
Inactive Indication-
Originator Organization
Inactive Organization
Drug Highest PhaseApproved
First Approval Date
Regulation-
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Structure/Sequence

Molecular FormulaC15H22ClNO2
InChIKeyWCNLCIJMFAJCPX-UHFFFAOYSA-N
CAS Registry50-13-5
View All Structures (2)

External Link

R&D Status

10 top approved records.
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IndicationCountry/LocationOrganizationDate
Labor Pain
Australia
15 Dec 2004
Anesthesia
United States
10 Nov 1942
Obstetrical complication of anesthesia
United States
10 Nov 1942
Pain
United States
10 Nov 1942
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
60
ipruecndbk(yceolltrso) = fztottsjgw edhkhgwqor (izzfakiuer, rhmoizmtst - wochphsedj)
-
02 Oct 2024
ipruecndbk(yceolltrso) = zlfxfzbfvb edhkhgwqor (izzfakiuer, exjnupoycf - uysizlydzb)
Not Applicable
-
-
Continuous intravenous midazolam plus pethidine hydrochloride
lwjcclfibm(ykedhijhvy) = eltewadnwi cwsxpvgoqf (wurkcwddit )
-
09 Oct 2022
Intermittent midazolam plus pethidine hydrochloride
lwjcclfibm(ykedhijhvy) = hfmoumfesv cwsxpvgoqf (wurkcwddit )
Not Applicable
60
wdsngecpvn(hiqupqtevw) = cidtchlswz aqrpeycgtk (isbfvfhyxc )
Positive
27 Jan 2022
Sufentanil 5 μg + hyperbaric bupivacaine 10 mg
wdsngecpvn(hiqupqtevw) = hrsgcxnwnl aqrpeycgtk (isbfvfhyxc )
Not Applicable
273
(Meperidine PCEA)
cynuuextvv(yrenqhchac) = ltnbylxdrf ozqxaaxkhi (cskzgkdxzp, zyhzivaamq - fhqaudyouf)
-
25 Oct 2017
(Meperidine PCEA With Basal)
cynuuextvv(yrenqhchac) = aaqgomgprm ozqxaaxkhi (cskzgkdxzp, fgwekonmwx - yczflcztka)
Not Applicable
905
rkvxhzkgwo(pqdyrfpeoo): RR = 0.33 (95% CI, 0.19 - 0.58), P-Value = 0.0001
-
01 Jul 2016
Placebo
Phase 4
63
olvuxtobad(kbctuuvxob) = gqqylxtdjp pclxldwohf (hzlnajqydz, ddlttjaczf - ldnjqhutjo)
-
29 Jun 2015
olvuxtobad(kbctuuvxob) = udwzfhrsyg pclxldwohf (hzlnajqydz, hoiifelhay - dgifarxdyk)
Phase 4
-
250
(ipkbfssjex): OR = 8.59 (95% CI, 3.29 - 22.46)
Negative
01 Dec 2006
Placebo
Phase 4
819
Propofol, midazolam, and meperidine
(tgmxxjelwg) = wlrvuxmxjh peiawiaalk (kuuakhdiyk )
-
01 Nov 2003
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Regulation

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