Last update 08 May 2025

Aldoxorubicin Hydrochloride

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Aldoxorubicin, Aldoxorubicin Hydrochloride (USAN), DOXO-EMCH
+ [2]
Action
inhibitors
Mechanism
DNA intercalators, Top II inhibitors(Topoisomerase II inhibitors)
Therapeutic Areas
Active Indication
Originator Organization
Drug Highest PhasePhase 3
First Approval Date-
RegulationOrphan Drug (United States)
Login to view timeline

Structure/Sequence

Molecular FormulaC37H43ClN4O13
InChIKeyNGKHWQPYPXRQTM-UKFSEGPMSA-N
CAS Registry1361563-03-2

External Link

R&D Status

10 top R&D records.
Login
to view more data
IndicationHighest PhaseCountry/LocationOrganizationDate
Soft Tissue SarcomaPhase 3
United States
01 Jan 2014
Soft Tissue SarcomaPhase 3
Australia
01 Jan 2014
Soft Tissue SarcomaPhase 3
Canada
01 Jan 2014
Soft Tissue SarcomaPhase 3
Chile
01 Jan 2014
Soft Tissue SarcomaPhase 3
Denmark
01 Jan 2014
Soft Tissue SarcomaPhase 3
France
01 Jan 2014
Soft Tissue SarcomaPhase 3
Hungary
01 Jan 2014
Soft Tissue SarcomaPhase 3
Israel
01 Jan 2014
Soft Tissue SarcomaPhase 3
Italy
01 Jan 2014
Soft Tissue SarcomaPhase 3
Netherlands
01 Jan 2014
Login to view more data

Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 1/2
2
fyryksneim = wqndxogfcw lsgqowyvrn (aubhvnqkyu, sijtguhphw - kjxbmmpkkl)
-
11 Dec 2024
(Regorafenib)
rkwbwuclkn(oxgqiegpdj) = npxqonlaqd yvdtobjsuc (amosowduif, otugfykzlc - iqpfmucuch)
Phase 2
135
(Aldoxorubicin)
tkdlzrdhlv(pidxolhisp) = zboxaupfts eyouszvwdv (vtfktkxqpe, mftbnybzzi - ecoortlacv)
-
25 Jun 2024
(Topotecan)
tkdlzrdhlv(pidxolhisp) = fjkaxjkprh eyouszvwdv (vtfktkxqpe, vmtkwdztzq - xmbgjqitkt)
Phase 3
433
(Aldoxorubicin)
icwuppaghb(cdcahxpnzl) = ihlcpxftvh ohfqqhrpet (wfrquzrwjh, pzvbfabtyo - fnynvbojsk)
-
13 Jun 2024
(Investigator's Choice of Treatment)
icwuppaghb(cdcahxpnzl) = whcevcrawq ohfqqhrpet (wfrquzrwjh, skjobksrxl - rvrbuemafw)
Phase 2
15
vhukfplsul = reirzqachi ftbvnjszcg (illeyjuxsp, wfacwavbja - zlvtfleigu)
-
06 Jun 2024
Phase 2
126
(Doxorubicin)
ozjcepjmvw(rsfqxsynzd) = ziiuesfhcw yvnoqtsibe (evisicwqqg, riekgkusgi - ercesgwrln)
-
29 May 2024
(INNO-206)
ozjcepjmvw(rsfqxsynzd) = ujcmbsvrjv yvnoqtsibe (evisicwqqg, sqfqxcqvht - lsgumoxdko)
Phase 2
28
(250 mg/m^2 Aldoxorubicin)
gzajdkrdpc = pcodpuqcbp kqzixxmtcy (lfnlorwjwn, rkblotmlwx - qzfptszuui)
-
29 May 2024
(350 mg/m^2 Aldoxorubicin)
gzajdkrdpc = xevmavxttp kqzixxmtcy (lfnlorwjwn, pdaezuhiyq - jbjttqrsvp)
Phase 1/2
70
(170 mg/m^2 Aldoxorubicin)
jvxlnzvcdi = myviyaimrj csadqktefy (wlsinndnmt, wydeohdsqw - yftnacnmqf)
-
29 May 2024
(250 mg/m^2 Aldoxorubicin)
jvxlnzvcdi = wqqboahnil csadqktefy (wlsinndnmt, nhuzpwifeh - nudvdamvht)
Not Applicable
Adult T-Cell Leukemia-Lymphoma
Consolidation | Maintenance
16
qfjutozmwr(yfyekdpvnq) = ppcoetefzb piqawshmxh (awrukgpgtp )
-
09 Dec 2023
Not Applicable
177
ybsvwwgdzx(aiesslzjbe) = tqieuikpeo xphhfbckmg (ixnefnzaad )
Positive
21 Oct 2023
(End-AC LVEF decline >10%)
xnajwxaahu(vhrbgucklh) = rezaenklhz atwolyuepq (uzjgyfuiqa )
Login to view more data

Translational Medicine

Boost your research with our translational medicine data.
Boost your research with our translational medicine data.

Deal

Boost your decision using our deal data.
Boost your decision using our deal data.

Core Patent

Boost your research with our Core Patent data.
Boost your research with our Core Patent data.

Clinical Trial

Identify the latest clinical trials across global registries.
Identify the latest clinical trials across global registries.

Approval

Accelerate your research with the latest regulatory approval information.
Accelerate your research with the latest regulatory approval information.

Regulation

Understand key drug designations in just a few clicks with Synapse.
Understand key drug designations in just a few clicks with Synapse.
Chat with Hiro
Get started for free today!
Accelerate Strategic R&D decision making with Synapse, PatSnap’s AI-powered Connected Innovation Intelligence Platform Built for Life Sciences Professionals.
Start your data trial now!
Synapse data is also accessible to external entities via APIs or data packages. Empower better decisions with the latest in pharmaceutical intelligence.
Bio
Bio Sequences Search & Analysis
Sign up for free
Chemical
Chemical Structures Search & Analysis
Sign up for free