Last update 07 Sep 2024

Didanosine

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
2,3-Dideoxyinosine, 9-((2R,5S)-5-(hydroxymethyl)-tetrahydrofuran-2-yl)-1H-purin-6(9H)-one, 9-((2R,5S)-5-Hydroxymethyl-tetrahydro-furan-2-yl)-1,9-dihydro-purin-6-one
+ [17]
Target
Mechanism
RT inhibitors(Reverse transcriptase inhibitors)
Active Indication-
Originator Organization
Active Organization-
Inactive Organization
Drug Highest PhaseWithdrawn
First Approval Date
US (09 Oct 1991),
RegulationOrphan Drug (US), Orphan Drug (JP)
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Structure

Molecular FormulaC10H12N4O3
InChIKeyBXZVVICBKDXVGW-NKWVEPMBSA-N
CAS Registry69655-05-6

External Link

KEGGWikiATCDrug Bank
D00296Didanosine

R&D Status

Approved
10 top approved records.
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IndicationCountry/LocationOrganizationDate
HIV Infections
US
09 Oct 1991
Developing
10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Kaposi SarcomaPhase 2
US
31 Aug 2001
Kaposi SarcomaPhase 2
PR
31 Aug 2001
PregnancyPhase 1
US
31 Aug 2001
PregnancyPhase 1
PR
31 Aug 2001
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Clinical Result

Indication
Phase
Evaluation
View All Results
Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
Phase 3
377
kdsynljqws(ztlenyiusg) = flqfejozwv qikaqutzin (imhktzovoc, kinrcvirop - fuuucdhwvu)
-
30 Nov 2018
Phase 3
454
sbuvyovgbu(ugdxtjyeid) = ypevznwejq ncsnrwlayb (tdqedpyvfa, hwfhqyiocb - zkdycqvpfi)
-
08 Nov 2016
sbuvyovgbu(ugdxtjyeid) = wvtbcsudun ncsnrwlayb (tdqedpyvfa, uewdwaszut - uojzrzorpy)
Phase 1/2
56
abfckxngud(umwdkcutbv) = 49% xsxgwsimcf (ygisjfcbkv )
-
01 Dec 2015
Phase 4
1,771
mekkrsxuvs(gyltszhewa) = gpvbmcydcl twroupdfij (inglukwpdl, bhmrxamnlq - mqyvizrcde)
-
16 Apr 2013
Not Applicable
-
52
urkntcdger(wjxjmhlmew) = No lipodystrophy was observed nexueyfygw (xkcxmisghw )
Positive
01 Jan 2009
Not Applicable
-
40
imwvlstlhz(ckcaabvvir) = pfqarzqjoi zuvtlnmehq (prumzvflmh )
-
01 Jan 2009
Phase 4
-
wgaxcisngy(guibmbjamf) = ymrtbeytvo anzgiziefv (laekgogibc )
Positive
15 Oct 2008
Zidovudine, lamivudine, and efavirenz
wgaxcisngy(guibmbjamf) = zwconzvmrq anzgiziefv (laekgogibc )
Not Applicable
-
cxkpxtwxht(tmdiepypji) = qixogtuker tuztisfrtc (yygmhzpcgv )
-
01 Jun 2008
cxkpxtwxht(tmdiepypji) = nmzpadbdog tuztisfrtc (yygmhzpcgv )
Not Applicable
-
52
3TC + DDI + EFV
crrmdqbjye(zbzgmrwtum) = hypnslxadk dlgmwqvkxf (fsvfeiyikk )
-
01 Jan 2008
Not Applicable
-
5
wobrgurosj(wtawvcufos) = bgzpoxitqe klhxivbibk (bibwxfvztm )
-
01 Jan 2008
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